Search clinical trials for: Cytochrome P-450 CYP3A Inhibitors

Total 7153 results

Organon and Co

Completed

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Diabetes Mellitus | Cardiovascular Disorder
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution

Pain Disorders

Switzerland
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Unknown

Risk of Tuberculous and Other Infections in Patients of Spondyloarthritis Treated With Tofacitinib in Bangladesh

Spondyloarthritis

Bangladesh
R-Pharm
GlaxoSmithKline

Terminated

Phase I Study of Ixabepilone Plus Lapatinib With or Without Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer

Locally Advanced or Metastatic Breast Cancer

United States, Italy, Australia
Eli Lilly and Company
Shionogi

Completed

A Study for the Treatment of Diabetic Peripheral Neuropathic Pain

Diabetic Neuropathies

Japan
Mylan Pharmaceuticals Inc

Completed

Fed Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
King Faisal University

Completed

Aminophylline and Cognitive Function After Sevoflurane Anaesthesia

Anaesthesia

Saudi Arabia
InnovaGyn, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Phase II Study of Ovulation in Obese Women

Pregnancy Prevention

United States
Merck Sharp & Dohme LLC

Completed

Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study

Non-Small-Cell Lung Carcinoma

Japan
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
Assaf-Harofeh Medical Center
Rambam Health Care Campus; Rabin Medical Center; HaEmek Medical Center, Israel; Tel-Aviv Sourasky Medical Center and other collaborators

Recruiting

Colorectal Metastasis Prevention International Trial 2 (COMPIT-2)

Colorectal Neoplasms

Israel
Services Institute of Medical Sciences, Pakistan

Completed

Letrozole vs Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovarian Syndrome

Polycystic Ovary Syndrome | Infertility

Pakistan
Xiaofan Wu

Unknown

Efficacy and Safety of Low Dose Ticagrelor in Patients With Unstable Angina Pectoris After Coronary Stent Implantation

Unstable Angina Pectoris | Coronary Stent Implantation

China
Zheng Liu ENT
Zhongnan Hospital; Wuhan Union Hospital, China; The People's Hospital of Hebei...

Recruiting

Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis

Allergic Rhinitis

China
Merck Sharp & Dohme LLC

Completed

Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)

Non-Small-Cell Lung Carcinoma
Janssen Scientific Affairs, LLC
Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.

Completed

Study to Evaluate the Effects of Tramadol Hydrochloride on Cardiac Repolarization in Healthy Participants

Healthy

United States
CONRAD

Completed

Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use

HIV Prevention

Dominican Republic, United States
Cancer Research UK

Terminated

NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United Kingdom
Sunovion

Completed

A Randomized, Placebo-Controlled, Two-Period, Crossover Study to Evaluate the Effect of Lurasidone HCl on Oral Contraceptive Pharmacokinetics in Healthy Female Subjects (OC-DDI)

Pharmacokinetics

United States
JHSPH Center for Clinical Trials
National Eye Institute (NEI)

Completed

Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial (MERIT)

Uveitis | Macular Edema

United States, Australia, Canada, India, United Kingdom
OHSU Knight Cancer Institute
Oregon Health and Science University; Kuni Foundation

Recruiting

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA Melanoma

Clinical Stage IIA Cutaneous Melanoma AJCC v8

United States
Shiraz University of Medical Sciences

Recruiting

Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi

Nephrolithiasis | Urinary Calculi | Urolithiasis | Ureterolithiasis

Iran, Islamic Republic of
Hospital de Clínicas Dr. Manuel Quintela
University of the Republic, Uruguay; Centro Cardiovascular Universitario; Centro...

Unknown

Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome (ENDPCS)

Venous Disease | Pelvic Congestive Syndrome | Pelvic Varices
University of Washington

Completed

Factors Affecting the Speed of Recovery After ACL Reconstruction

Anterior Cruciate Ligament Injury | ACL Injury | ACL - Anterior Cruciate Ligament Rupture

United States
Gruppo Italiano per lo studio dei Carcinomi dell...
Mario Negri Institute for Pharmacological Research

Unknown

Metastatic Advanced Pancreas Sorafenib (MAPS)

Locally Advanced Pancreatic Cancer

Italy
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs

Healthy

Korea, Republic of
The First Affiliated Hospital of Xiamen University

Recruiting

Graves' Disease Remission Study: MycoMeth Combo (3M-RGD)

Graves' Disease

China
Mohamed Tahar Maamouri University Hospital

Completed

Clinical Performance of Therapeutic Use of BTX for Bruxism (BTX)

Pain | Bruxism | Myofascial Pain Syndrome | Myofascial Trigger Point Pain

Tunisia
Lanzhou Institute of Biological Products Co., Ltd

Unknown

A Study to Evaluate the Efficacy and Safety of Botulinum Toxin Type A in Patients With Overactive Bladder (OAB)

Overactive Bladder
University of Zurich
Swiss Federal Institute of Technology

Completed

Exceptional Experiences (EE), Salience & Dopaminergic Neurotransmission

Healthy | Schizotypal Personality

Switzerland
MedImmune LLC

Completed

A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation, Spain, United Kingdom, Argentina, Hungary, Israel, Portugal, Slovakia, Greece, Serbia, Czech Republic, Colombia, France, Mexico
Cambridge University Hospitals NHS Foundation Trust
Anticancer Fund, Belgium

Completed

A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer (PIONEER)

Breast Cancer

United Kingdom
GlaxoSmithKline

Terminated

Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza

Virus Diseases

United States, Sweden, Russian Federation, Romania
Hospital de Manises
Merck Sharp & Dohme LLC; Hospital Arnau de Vilanova; Hospital Universitario La... and other collaborators

Unknown

Optimization of Golimumab Treatment in Ulcerative Colitis

Colitis, Ulcerative

Spain
ASST Fatebenefratelli Sacco

Not yet recruiting

A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy

Pain
Sound Pharmaceuticals, Incorporated
University of Florida

Completed

Otoprotection With SPI-1005 for Prevention of Temporary Auditory Threshold Shift

Temporary Auditory Threshold Shift

United States
University of Saskatchewan

Recruiting

Three Dimensional Ultrasonographic Detection of Human Ovulation

Ovulation Disorder

Canada
Bial - Portela C S.A.

Completed

Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics

Parkinson Disease

Portugal
Seagen Inc.
Genentech, Inc.

Completed

Study of SGN-40, Lenalidomide, and Dexamethasone in Patients With Multiple Myeloma

Multiple Myeloma

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Citalopram Hydrobromide Tablets 40 mg of Dr.Reddy's Laboratories Limited Under Fed Conditions

Healthy

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor

Stage I Adrenal Cortical Carcinoma AJCC v7 | Stage II Adrenal Cortical Carcinoma AJCC v7 | Stage III Adrenal Cortical Carcinoma AJCC v7 | Stage IV Adrenal Cortical Carcinoma AJCC v7

United States, Canada, Australia, Brazil
Minia University

Completed

Methotrexate Infusion and Intrasilicone Injection During Diabetic Vitrectomy

Diabetic Retinopathy | Vitreomacular Traction

Egypt
Combined Military Hospital, Pakistan

Completed

Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin

Tonsillitis Streptococcal

Pakistan
Genentech, Inc.

Completed

A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands, Canada
Janssen Biotech, Inc.
Merck Sharp & Dohme LLC

Completed

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Autoimmune Diseases | Arthritis | Arthritis, Rheumatoid

United States, United Kingdom, Belgium, Greece, Canada, Germany, Sweden, Austria
LG Chem

Unknown

Clinical Trial to Compare the PK of the Fixed-dose Combinations and Each Component of Gemigliptin/Dapagliflozin 50/10 mg

T2DM
HK inno.N Corporation

Completed

Effect of Tegoprazan or RAPA113 on Pharmacodynamics/Pharmacokinetics of Clopidogrel in Healthy Male Volunteers

Healthy

Korea, Republic of
Brainfarma Industria Química e Farmacêutica S/A

Not yet recruiting

Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolated Drugs in the Treatment of Hypertension. (OLINDA)

Hypertension | Hypertension,Essential
Lundquist Institute for Biomedical Innovation at...
Abbott Nutrition; DaVita Dialysis

Completed

Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients (AIONID)

Inflammation | Oxidative Stress | Hypoalbuminemia | Protein-energy Malnutrition | Chronic Kidney Disease (CKD) Hemodialysis

United States
Baylor College of Medicine

Completed

Chemotherapy With or Without Radiation, Low and Intermediate Risk Hodgkins Lymphoma, TXCH-HD-12A (TXCH-HD-12A)

Hodgkin Disease

United States

Search clinical trials for: Cytochrome P-450 CYP3A Inhibitors

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