Search clinical trials for: Daratumumab dose escalation

Total 6751 results

Merck Sharp & Dohme LLC

Withdrawn

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

Multiple Myeloma

United States, Canada, France, Israel, Spain, Sweden
First Affiliated Hospital of Zhejiang University

Recruiting

The Safety and Efficacy of CD38 Monoclonal Antibody Monotherapy for CaAMR in Renal Transplantation

Antibody-mediated Rejection | Kidney Tranplant

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Daratumumab-containing Induction Effects on Stem Cells Mobilization, colLection and Engraftment in Newly Diagnosed Multiple MyelomA Patients. (DILEMMA)

Multiple Myeloma | Daratumumab | Autologous Stem Cell Transplantation | Leukapheresis

Italy
University of Tetova
University of Tetova, Faculty of Medical Sciences

Completed

Role of Antioxidants in the Reduction of Oxidative Stress in Infertile Patients (OAT)

Infertility | Male | Oligoasthenozoospermia

North Macedonia
Kyoto Drug Discovery and Development Co., Ltd.

Recruiting

A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arthritic Central Retinal Artery Occlusion (CRAO) (GION)

Central Retinal Artery Occlusion

United States
Biocad

Recruiting

Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

Hemophilia B

Russian Federation
Canadian Cancer Trials Group

Recruiting

Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer

Prostate Carcinoma

Canada
Lexicon Pharmaceuticals

Completed

Efficacy, Safety, and PK of LX9211 in Patients With Diabetic Peripheral Neuropathic Pain (RELIEF-DPN 1)

Diabetes | Diabetic Peripheral Neuropathy

United States
Xuzhou Central Hospital

Completed

Low-dose Computed Tomography-guided Core Needle Biopsy for Lung Nodules

Lung Cancer | Lung; Node

China
Sun Pharma Advanced Research Company Limited

Completed

Study of SPARC1103 in Subjects With Spasticity

Spasticity

United States, Russian Federation, Ukraine
University Health Network, Toronto

Terminated

Ultralow Dose Thoracic Computed Tomography in Immunocompromised Patients (ULDCT-IC)

Leukemia

Canada
GlaxoSmithKline

Completed

Phase I Study of GW856553 (Losmapimod)

Acute Coronary Syndrome

Australia
University of Alabama at Birmingham
Pfizer

Completed

High Dose CVVHDF Compared to Standard Dose CVVHDF (CVVHDF)

Acute Renal Failure

United States
Seoul National University Bundang Hospital
GE Healthcare; National Research Foundation of Korea

Completed

Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT

Appendicitis

Korea, Republic of
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
University of Cologne
Janssen-Cilag G.m.b.H

Recruiting

Daratumumab for First Line Treatment of Transplant-ineligible Myeloma Patients Followed by Daratumumab Re-treatment at First Relapse (GMMG-DADA)

Multiple Myeloma

Germany
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Daratumumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome

United States
AbbVie
AbbVie

Recruiting

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) Without Center Involved-Diabetic Macular Edema (CI-DME) (ALTITUDE)

Diabetic Retinopathy (DR)

United States
China Academy of Chinese Medical Sciences

Recruiting

The Dose-Effect Relationship of Wenxin Granules in the Treatment of Atrial Premature Beats

Atrial Premature Complexes

China
Chiesi Farmaceutici S.p.A.

Active, not recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF

Idiopathic Pulmonary Fibrosis

North Macedonia, Ukraine, United Kingdom
Dr. Falk Pharma GmbH

Completed

Trichuris Suis Ova (TSO) Suspension Versus Placebo in Active Crohn's Disease (TRUST-2)

Crohn´s Disease

Germany
Sir Run Run Shaw Hospital

Recruiting

Molecular Basis of Loss Aversion

Healthy

China
Rznomics, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Korea, Republic of
Boehringer Ingelheim

Completed

BIRB 796 BS Versus Placebo in Patients With Moderate to Severs Plaque-type Psoriasis

Psoriasis
Seoul National University Hospital
Green Cross Corporation; LSK Global Pharma Services Co. Ltd.

Completed

Efficacy and Safety of Anthrax Vaccine, GC1109

Anthrax

Korea, Republic of
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection
Universidade Cidade de Sao Paulo

Completed

Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation (preterm)

Preterm Birth
LTN PHARMACEUTICALS, INC.

Completed

ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer (ARMOR1)

Prostate Cancer

United States
Ikena Oncology
Gilead Sciences

Terminated

A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Gastric Adenocarcinoma | Lung Adenocarcinoma | Advanced Solid Tumor

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Study of HS-10517 in Chinese Adult Participants

COVID-19

China
Centre Jean Perrin

Recruiting

Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012 (MELRIV-1)

Melanoma

France
Biocad

Terminated

Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (COVER)

COVID-19 | Coronavirus Infection

Russian Federation
University of Oxford
European Commission

Completed

A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5

Malaria | Plasmodium Falciparum

United Kingdom
Rob Erskine
University of East Anglia

Completed

Acute Resistance Exercise and Hydrolyzed Collagen Supplementation

Diet | Nutrition | Food

United Kingdom
NYU Langone Health

Completed

TA-65 Pharmacokinetic Study

Healthy

United States
Aerie Pharmaceuticals

Completed

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Fu-Sheng Wang

Unknown

Umbilical Cord Mesenchymal Stem Cells for Immune Reconstitution in HIV-infected Patients

Human Immunodeficiency Virus | Disorder of Immune Reconstitution

China
GlaxoSmithKline

Completed

Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
Apnimed

Completed

Trial of AD036 in Obstructive Sleep Apnea

Obstructive Sleep Apnea

United States
Aventure AB

Completed

Second Meal Effects of a Wholegrain Cereal Product on Blood Glucose Response

Blood Glucose Response

Sweden
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus

Obesity and Diabetes Mellitus, Type 2

United States
Shire

Completed

Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)

Metachromatic Leukodystrophy (MLD)

Denmark
Knopp Biosciences
Biogen

Completed

Dexpramipexole Japanese PK Study

Amyotrophic Lateral Sclerosis

United Kingdom
Allergan

Completed

AGN-199201 for the Treatment of Erythema With Rosacea

Erythema | Rosacea

United States
Pfizer

Completed

A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease

Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | COPD | Chronic Obstructive Airway Disease

Germany
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Transfusion Medicine/Hemostasis...

Completed

Optimal Platelet Dose Strategy for Management of Thrombocytopenia (PLADO)

Thrombocytopenia

United States
MediciNova

Completed

Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
Hong Kong Baptist University

Completed

A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation

Constipation

China
Oslo University Hospital
University Hospital of North Norway; Helse Stavanger HF; Haukeland University... and other collaborators

Recruiting

The Relapse From MRD Negativity as Indication for Treatment (REMNANT) Study

Multiple Myeloma

Norway
Israel Institute for Biological Research (IIBR)

Completed

Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine

Covid19

Israel

Search clinical trials for: Daratumumab dose escalation

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