Search clinical trials for: De-escalation

Total 930 results

Avenge Bio, Inc

Terminated

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer | Primary Peritoneal Carcinoma | Neoplasm, Ovarian | Adenocarcinoma Ovary | Serous Adenocarcinoma of Ovary | Serous Adenocarcinoma of Primary Peritoneum | High Grade Serous Adenocarcinoma

United States
Pfizer

Terminated

Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations

Parkinson's Disease With Motor Fluctuations

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Santen Pharmaceutical Co., Ltd.

Completed

Late Phase II Confirmatory Study of DE-089 Ophthalmic Solution in Patients With Dry Eye

Dry Eye

Japan
Santen Pharmaceutical Co., Ltd.

Completed

Study of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect

Persistent Corneal Epithelial Defect

Japan
Universidade Cidade de Sao Paulo

Completed

Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation (preterm)

Preterm Birth
M.D. Anderson Cancer Center

Recruiting

Fecal Microbial Transplants for the Treatment of Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
Pierre Fabre Medicament

Active, not recruiting

A Study of a New Investigational Medicinal Product to Treat Patients With Advanced or Metastatic Solid Tumors (Ulysse)

Advanced or Metastatic Solid Tumors

France, Spain
Liz Darling
London Health Sciences Centre; Trillium Health Partners; Oak Valley Health

Not yet recruiting

Oral Sodium Bicarbonate for the Prevention of Labour Dystocia (Labour-Aide)

Labour Dystocia
Queen's University
Canadian Institutes of Health Research (CIHR)

Completed

Evaluating Chronic Pain Self-Management Support With an Opioid De-prescribing Intervention

Chronic Pain

Canada
University of Oklahoma
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Metabolic Pathology of Pediatric NAFLD

Obesity | Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

United States
Cairo University

Not yet recruiting

Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities

Class I Dental Caries
Nouran Abdulla Mater,MD

Unknown

Pontic Site Development Using Soft Tissue Augmentation

Alveolar Bone Loss

Egypt
London North West Healthcare NHS Trust

Unknown

De-roofing and Curettage vs WLE for Pilonidal Abscess

Pilonidal Disease | Pilonidal Abscess | Pilonidal Sinus With Abscess | Pilonidal Sinus Infected
Lund University

Completed

Factors Responsible for the Effectiveness of the Lund De-airing Technique

Complication of Surgical Procedure

Sweden
Shanghai Jiao Tong University School of Medicine

Recruiting

Escalation Antifungal Prophylaxis for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Fungal Infection

China
Emory University
Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Completed

Protocol of the Combination of Bortezomib and Tipifarnib for Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Canada
Santen Pharmaceutical Co., Ltd.

Completed

Assessing Safety and Efficacy of DE-089 Ophthalmic Solution in Patients With Dry Eye Disease

Dry Eye Disease

Taiwan
Princess Al-Johara Al-Ibrahim Cancer Research Center

Completed

Escalating, Constant and Reduction Energy Output in SWL for Renal Stones (SWL)

Renal Stones

Saudi Arabia
NorthShore University HealthSystem

Completed

The Cascade Feasibility Pilot (HF) Phase 3

Heart Failure

United States
University of Michigan Rogel Cancer Center
Phase One Foundation

Completed

Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma

Glioblastoma Multiforme | Malignant Glioma

United States
Radboud University Medical Center
Novartis

Completed

Influence of Exceptional Patient Characteristics on Everolimus Exposure (INPRES)

Breast Neoplasms

Netherlands
University of Sao Paulo

Completed

Non-carious Cervical Lesions and Treatments (NCCL)

Tooth Sensitivity

Brazil
Professor Fernando Figueira Integral Medicine Institute

Completed

A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy

Preterm Birth | Magnesium Deficiency | Extreme Immaturity

Brazil
Haukeland University Hospital
Helse-Bergen HF

Completed

Volar Locked Plating vs Bridging External Fixation in Distal Radius Fracture

Distal Radius Fracture

Norway
Institut Curie

Recruiting

First-in-human Phase I to Evaluate PEP-010 as Single Agent and in Combination With Paclitaxel or With Gemcitabine (CleverPeptide)

Metastatic Solid Tumor Cancer

France
Kazia Therapeutics Limited

Completed

Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.

Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms

United States, Australia
Theagenio Cancer Hospital

Unknown

Cisplatin Chemoradiation With or Without Cetuximab for Locoregionally Advanced Squamous Cell Carcinomas (SCC) of the Head and Neck

Head and Neck Neoplasms | AJCC Stage III/IV

Greece
GlaxoSmithKline

Completed

Intra Oral Kinetics of Fluoride Containing Dentifrices

Tooth Erosion

United Kingdom
Petros Dinas

Completed

The Effects of Chronic Exercise on UCP1 Gene in Human White Adipose Tissue

Obesity | Obese

Greece
AGC Biologics S.p.A.

Completed

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

Advanced Solid Tumors

Italy
Ottawa Hospital Research Institute

Recruiting

Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance (REaCT-TEMPO)

Breast Cancer

Canada
Alfonso Gomez-Iturriaga
Hospital de Cruces

Unknown

Dose Escalation to Dominant Intraprostatic Lesions (DIL) With MRI-TRUS Fusion High Dose Rate (HDR) Prostate Brachytherapy (BRAPROST)

Prostate Cancer

Spain
Thai Gynecologic Oncology Collaborative Group
National Research Council of Thailand; Clinical Research Collaborative Network

Unknown

Comparing Study Between Concurrent Chemoradiation and New Combination Treatment in Cervical Cancer Patients (TGOCphaseIII)

Cervical Cancer

Thailand
GamaMabs Pharma

Completed

First In Human Safety, Pharmacokinetics and Anti-tumoral Activity of GM102 in Gynecological Cancers

Neoplasm, Gynecologic

France, Belgium, United Kingdom
Corina Schuster-Amft

Not yet recruiting

Feasibility, Safety and Performance Evaluation of an Application Based Training Programme for Patients After a Stroke (TeleRehaStroke)

Stroke

Switzerland
Nantes University Hospital
Jazz Pharmaceuticals

Completed

Pharmaco-economic Study of a New Medical Device Performed From the Perspective of the Hospital (Caphosol)

Hematologic Disease

France
Centro de estudios en Cardiologia Intervencionista
Eucatech AG

Completed

A Trial Comparing a Paclitaxel Eluting Stent With Biodegradable Polymer Versus a Bare Metal Stent (EUCATAX)

Coronary Artery Disease

Argentina
Universidade Federal Fluminense

Unknown

Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth (Caries_removal)

Dental Caries Extending Into Dentin
Asana BioSciences

Terminated

Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate Resistant Prostate Cancer

Prostate Cancer | Cancer of the Prostate | Neoplasms, Prostate | Prostatic Cancer | Neoplasms, Prostatic | Prostate Neoplasms, Castration-resistant

United States
University Rovira i Virgili
University of Valladolid; Sanidad de Castilla y León

Unknown

Optimal Heating Temperature in Major Burns Patients

Burns | Nurse's Role | Thermal Injury
Cancer Research UK
BioInvent International AB; Bloodwise

Completed

BI-1206 and an Anti-CD20 Antibody in Patients With CD32b Positive B-cell Lymphoma or Leukaemia

B-cell Lymphoma | Waldenström Macroglobulinemia | Chronic Lymphocytic Leukaemia

United Kingdom
Cairo University

Completed

Evaluation of SECTG Vs. Laser-DGG in Management of Gingival Recessions.

Gingival Recession

Egypt
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Bortezomib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer

United States
University Hospital, Geneva
Bayer

Completed

Sorafenib in Newly Diagnosed High Grade Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

Switzerland
Brii Biosciences Limited

Completed

A Study of BRII-297 in Healthy Adult Subjects

Postpartum Depression

Australia
Universidad de León
Consejo General de Colegios Oficiales de Enfermería España

Completed

Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain)

Alzheimer Disease

Spain
University of Nebraska Lincoln
Johns Hopkins University

Completed

A Family-Centered Ojibwe Substance Abuse Prevention (BZDDD)

Substance Use

Search clinical trials for: De-escalation

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