Search clinical trials for: Debio 1450

Total 6668 results

Centre Hospitalier Universitaire, Amiens

Recruiting

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

Mycobacterium Avium Complex | Lung Infection

France
Zhejiang ACEA Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Relative Bioavailability of STI-1558 and the Effect of Itraconazole and Rifampin on the Pharmacokinetics of STI-1558

COVID-19 Pneumonia

China
Celgene Corporation

Completed

Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibition and Induction on the Pharmacokinetics of CC-220 in Healthy Subjects

Pharmacokinetics

United States
Vantia Ltd

Completed

Study in Healthy Male Subjects to Evaluate the Effect of Itraconazole and Rifampicin on the PK of Fedovapagon

Nocturia

Germany
Procter and Gamble

Completed

Evaluation of the Anticaries Efficacy of Dentifrice Formulations Using an In-situ Model

Caries

Australia
Radboud University Medical Center

Recruiting

Pragmatic Optimized Rifampicin Trial (PORT)

Tuberculosis, Pulmonary

Netherlands
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

Genetic Disease | Hypercalciuria | Idiopathic Infantile Hypercalcemia - Mild Form | Idiopathic Infantile Hypercalcaemia - Severe Form | Hypercalcemia, Idiopathic, of Infancy | Hypercalciuric Hypercalcemia

United States
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects

Healthy Subject

Netherlands
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
R-Pharm

Completed

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

Neoplasms | Advanced Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib

Healthy Adult Subjects

China
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
Pfizer

Completed

A Study To Evaluate The Effect Of Rifampin On Pharmacokinetics Of PF-06463922 In Healthy Volunteers

Healthy

United States
Eisai Limited

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Eribulin Mesylate in Participants With Advanced Solid Tumors

Tumor

Netherlands
University of California, San Francisco
Makerere University; Infectious Diseases Research Collaboration, Uganda; Makerere...

Completed

Early HIV Therapy in Patients With High CD4 Cell Counts (EARLI)

HIV

Uganda
Indiana University
Janssen Services, LLC

Completed

Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress

Cardiovascular Disease

United States
Radboud University Medical Center
Sanofi; European and Developing Countries Clinical Trials Partnership (EDCTP); National Institute for Public Health and the Environment (RIVM) and other collaborators

Completed

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis (High RIF)

Tuberculosis

Tanzania
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Phase I, Open-label Trial to Explore the Pharmacokinetics, Safety and Tolerability of TMC278 (Rilpivirine) 25 mg Once Daily Following a 2-week Period Receiving Efavirenz, in Healthy Male and Female Volunteers

HIV
Center for Clinical Pharmacology Research Bdbeq...
University of the Republic, Uruguay

Completed

Efavirenz Comparative Bioavailability (efv600)

Healthy

Uruguay
University of Campania "Luigi Vanvitelli"
Federico II University

Completed

Colistin and Rifampicin for MDR-Acinetobacter (CoRAb)

Pneumonia, Ventilator-Associated | Hospital Acquired Pneumonia | Infection Due to Resistant Bacteria | Infection of Bloodstream | Infectious Disease of Abdomen
Bristol-Myers Squibb

Completed

Effectiveness and Safety of Two Forms of Stavudine in HIV-Infected Patients

HIV Infections

United States, Canada, Belgium, Mexico, Italy, France, Argentina, Israel, Spain, Brazil, Puerto Rico, Australia, Portugal, Russian Federation, South Africa, Thailand
Hoffmann-La Roche

Completed

A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients

HIV Infections

United States
TYK Medicines, Inc

Recruiting

Studies Evaluating the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of TY-9591 Tablets in Healthy Subjects

NSCLC

China
Vigonvita Life Sciences

Completed

Drug-Drug Interaction (DDI) Study for TPN171H

Erectile Dysfunction

China
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

CYP3A4 Activity and Mineral Homeostasis

Vitamin D and Calcium Homeostasis

United States
Hutchmed

Completed

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Relapsed or Refractory Lymphoma

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Loxo Oncology, Inc.

Completed

Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants

Healthy Volunteers

United States
Assiut University

Unknown

Comparison Between Rifampicin and Gemifloxacin and Ciprofloxacin in Treatment of Rhinoscleroma

Rhinoscleroma

Egypt
National Jewish Health

Completed

Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium-intracellulare Infection
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

Tuberculosis

United States
Tammie L. S. Benzinger, MD, PhD

Recruiting

Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND) (HASD_PIB_IND)

Alzheimer Disease

United States
University of Virginia
Rutgers University; Haydom Lutheran Hospital

Not yet recruiting

Precision Rifampin Trial for Personalized Dosing (P-RIF)

Tuberculosis
Hospital Universitari Vall d'Hebron Research Institute
Radboud University Medical Center; University Medical Center Groningen; Centro... and other collaborators

Not yet recruiting

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (RIAlta)

Tuberculosis

Spain, Netherlands, Paraguay, Portugal
Suzhou Yabao Pharmaceutical R&D Co., Ltd.

Completed

A Drug Interaction Study of SY-004 Capsules in Healthy Subjects

Type 2 Diabetes

China
Pfizer

Completed

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Healthy Volunteers

Belgium
Hospices Civils de Lyon

Completed

Staphylococcal Acute Post-Operative PJI Treated With 'DAIR' And Impact Of Rifampin (IPASTAPH)

Bone and Joint Infection | Antibiotic Resistant Staphylococcus Aureus Infection

France
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan

Healthy Subjects

Netherlands
PTC Therapeutics

Completed

Effects of Rifampin on the Pharmacokinetics of Ataluren

Healthy

Canada
Boehringer Ingelheim

Completed

DDI Strong CYP3A4 Inducer

Healthy

Germany
Drexel University

Completed

Immune Activation and Drug Absorption in HIV-Infected Patients

HIV Infection

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C215: A Clinical Trial in Treatment Naive HIV-subjects Patients Comparing TMC278 to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors

HIV Infections | HIV-1

United States, France, United Kingdom, China, Belgium, Germany, Spain, Chile, Mexico, Portugal, Costa Rica, Panama, South Africa, Canada, Brazil, Puerto Rico, Russian Federation, Thailand, Australia, India
Bayer

Completed

Effect of Rifampin on the Pharmacokinetics of BAY73-4506

Neoplasms

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
All India Institute of Medical Sciences, New Delhi
National AIDS Control Organisation

Completed

Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB ("NVP")

HIV/TB Co-infection

India
University of Oulu

Completed

Effects of Pregnane X Receptor (PXR) Activation on Human Glucose, Lipid and Hormone Homeostasis (Rifa-2)

Glucose Metabolism

Finland
Centers for Disease Control and Prevention

Completed

High Dose Rifapentine Pharmacokinetics, Tolerability and Safety Dosage Rifapentine for Treatment of Tuberculosis (TBTC-29PK)

Smear Positive, Pan-sensitive, Pulmonary Tuberculosis

United States, South Africa, Uganda
Mahidol University

Unknown

Colistin Plus Rifampicin in MDR P. Aeruginosa and A. Baumanii

Drug Safety

Thailand
University of Oulu

Completed

Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis

Glucose Tolerance

Finland

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