Search clinical trials for: Denosumab-Ref

Total 2043 results

Lambda Therapeutic Research Ltd.
Intas Pharmaceutical Limited (Biopharma Division)

Recruiting

Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

India
Centre Leon Berard

Terminated

Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies (MOSCAR)

Metastatic Renal Cell Carcinoma

France
Turku University Hospital
Amgen

Completed

Denosumab in Enhancement of Bone Bonding of Hip Prosthesis in Postmenopausal Women (ProliaHip)

Hip Osteoarthritis

Finland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell Disease (ARCAD)

Acute Chest Syndrome

France
Terumo BCTbio
United States Department of Defense; U.S. Army Medical Research and Development... and other collaborators

Terminated

Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE) (PRAISE)

Transfusion Dependent Thalassemia

United States, Israel, Italy, Turkey
Alfredo Gamboa
Vanderbilt University Medical Center

Withdrawn

Breathing Device for Orthostatic Hypotension (OH)

Orthostatic Hypotension

United States
Parker University
University of Miami; University of Houston; Whittier University

Completed

Extremity Manipulation Impact on Postural Sway Characteristics (Balance1)

Healthy

United States
Samsung Bioepis Co., Ltd.

Completed

A Study to Compare SB16 (Proposed Denosumab Biosimilar) to Prolia® in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

Poland
Amgen

Completed

Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis

Osteoporosis | Osteopenia | Low Bone Mineral Density | Low Bone Mass | Males With Osteoporosis
GlaxoSmithKline

Completed

A Study in Korean Postmenopausal Women With Osteoporosis to Evaluate the Efficacy and Safety of Denosumab

Osteoporosis, Postmenopausal

Korea, Republic of
Amgen

Completed

Bioequivalence Study of Denosumab CP4 Drug Product and Commercially Available Denosumab CP2 Drug Product

Healthy Volunteer

United States
Borstkanker Onderzoek Groep
Amgen

Withdrawn

Study to Identify the Impact of Denosumab on the Immune System in Patients With HER2 Negative Breast Cancer (PERIDENO)

Breast Neoplasms

Netherlands
Amgen

Completed

A Double-blind Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

United States, Denmark, Poland, Canada
Swiss Group for Clinical Cancer Research

Active, not recruiting

Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks

Metastatic Breast Cancer | Bone Metastases | Metastatic Prostate Cancer

Switzerland, Germany, Austria
Luye Pharma Group Ltd.
Parexel

Completed

A Pharmacokinetic Similarity Study in Healthy Male Subjects to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of LY06006 Versus US-Prolia and EU-Prolia by Single-dose Subcutaneous Injection

Healthy

Germany
GlaxoSmithKline

Completed

China HVT Safety, PK, PD

Osteoporosis

China
Alfredo Gamboa
Vanderbilt University Medical Center

Active, not recruiting

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

Postural Tachycardia Syndrome | Postural Orthostatic Tachycardia Syndrome

United States
Boston University

Completed

Testing the Re-Engineered Hospital Discharge

All

United States
National Cancer Institute (NCI)

Terminated

Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy

Ovarian Carcinoma

United States, Israel
Tartu University Hospital
University of Tartu

Completed

The Effect of FES and Therapeutic Exercise on SCI Patients Skeletal Muscles, Sitting Balance, Posture and Quality of Life

Spinal Cord Injuries

Estonia
National Institute of Dental and Craniofacial Research...

Recruiting

Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia

Fibrous Dysplasia

United States
Shanghai JMT-Bio Inc.

Completed

A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
GlaxoSmithKline

Completed

A Study in Indian Postmenopausal Women With Osteoporosis to Evaluate the Efficacy and Safety of Denosumab

Osteoporosis, Postmenopausal

India
Amgen

Completed

Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab

Relapsed or Plateau-Phase Multiple Myeloma
Amgen

Completed

A Multi-Center, Randomized, Open-Label Study to Assess the Immunogenicity and Safety of Denosumab in Pre-filled Syringe Compared to Vial in Subjects With Low Bone Mineral Density

Osteoporosis | Osteopenia | Low Bone Mineral Density
Amgen

Completed

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Lymphoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Non-Small Cell Lung Cancer | Lung Cancer | Metastatic Cancer | Colon Cancer | Thyroid Cancer | Renal Cancer | Parathyroid Neoplasms | Endocrine Cancer | Hypercalcemia of Malignancy

United States, Italy, France, Canada, Poland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma

United States, Canada, Puerto Rico
Indiana University

Withdrawn

Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders

Vasculitis | Osteoporosis | Dermatomyositis | Juvenile Rheumatoid Arthritis | Glucocorticoid-induced Osteoporosis | Polyarthritis | Systemic Lupus Erythematosis

United States
HealthEast Care System
Amgen

Completed

Longitudinal Effects of Denosumab on Trabecular Bone Score and Femur Strength Index

Osteoporosis | Bone Fracture

United States
Alvotech Swiss AG

Completed

AVT03 With Prolia in Healthy Male Subjects

Healthy Male Subjects

New Zealand
Nigde Omer Halisdemir University

Completed

Efficacy of Denosumab Treatment in Bisphosphonate Unresponsive Patients

Postmenopausal Osteoporosis

Turkey
Albert Einstein Healthcare Network
Amgen

Withdrawn

A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time Liver Transplant Recipients.

Osteoporosis
Rudolf Wuethrich

Completed

Denosumab for Prevention of Osteoporosis in Renal Transplant Recipients (POSTOP)

Chronic Kidney Disease | Osteoporosis

Switzerland
Ole Lander Svendsen

Recruiting

The DENOCHARCOT Trial

Diabetes Mellitus | Charcot Foot

Denmark
Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

Continued Access Protocol (CAP-AF)

Atrial Fibrillation

United States
NYU Langone Health

Completed

Presurgical Trial of Denosumab in Breast Cancer

Breast Cancer

United States
Amgen

Completed

Characteristics and Management of Postmenopausal Women With Osteoporosis Treated With Prolia® in France (PILOTE)

Post Menopausal Osteoporosis

France
Seoul National University Bundang Hospital

Unknown

Comparative Study for Incidence of Proximal Junctional Kyphosis Between Parathyroid Hormone and Denosumab Following Adult Spinal Deformity Surgery : A Prospective, Randomized Controlled Trial

Spine Deformity

Korea, Republic of
Qilu Pharmaceutical Co., Ltd.

Unknown

Comparing of the Pharmacokinetic, Safety and Pharmacodynamic of QL1206 and Prolia® in Healthy Adults

Healthy People

China
Amgen

Completed

A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab

Osteoporosis | Postmenopausal Osteoporosis | Low Bone Mineral Density | Low Bone Mass
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety of Recombinant HIV Vaccines in HIV Infected Young Adults on Stable Therapy

HIV Infections

United States, Puerto Rico
Shenzhen People's Hospital

Withdrawn

Denosumab and Screw Fixation for Osteoporotic Compression Fracture

Denosumab Allergy

China
Massachusetts General Hospital
Emory University; University of Rochester; Amgen; University Hospitals Cleveland...

Unknown

A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency

Multiple Myeloma

United States
Peking University People's Hospital

Completed

Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts (Deno-ABC)

Recurrent Disease | Pathological Fracture | Refractory Tumor | Bone Cyst Aneurysmal
Istituto Ortopedico Rizzoli

Completed

Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment (GCTLIMBS)

Giant Cell Tumor of Bone
Shenzhen People's Hospital

Recruiting

Denosumab vs Zoledronate After Lumbar Fusion

Osteopenia | Lumbar Spondylolisthesis

China
Amgen

Completed

Denosumab Adherence Preference Satisfaction Study

Osteoporosis
Amgen

Completed

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Aromatase Inhibitor Therapy for Non-metastatic Breast Cancer

Breast Cancer | Osteopenia | Low Bone Mineral Density
Mayo Clinic

Completed

Osteoclast Inhibition and Bone Formation

Aging | Bone Loss

United States
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Terminated

The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury

Spinal Cord Injury | Secondary Osteoporosis

United States

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