Search clinical trials for: diquafosol tetrasodium (INS365) ophthalmic solution

Total 1459 results

Merck Sharp & Dohme LLC

Completed

A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

A Study of INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637)

Dry Eye Disease
Merck Sharp & Dohme LLC

Terminated

A Double-masked, Randomized, Placebo-controlled,Pilot Study of Diquafosol Tetrasodium in Subjects Following Photorefractive Keratectomy (PRK)

Photorefractive Keratectomy
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Diquafosol Tetrasodium Ophthalmic Solution, 2% Versus Placebo in Dry Eye Subjects (P08634)

Dry Eye Disease
Peking University Third Hospital

Recruiting

The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye

Dry Eye Syndromes | Computer Vision Syndrome | Asthenopia

China
He Eye Hospital

Not yet recruiting

Diquafosol vs Hyaluronic Acid for Diabetic Dry Eye

Diabetic Eye Problems

China
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in a Controlled Adverse Environment in Patients With Dry Eye

Keratoconjunctivitis Sicca
He Eye Hospital

Not yet recruiting

Diquafosol Ophthalmic Solution for Dry Eye Symptoms

Diabetic Eye Problems

China
He Eye Hospital
Santen Pharmaceutical(China) Co.,LTD

Not yet recruiting

Use of 3% Diquafosol Topical Ophthalmic Solution for Diabetic Dry Eye

Diabetic Eye Problems

China
He Eye Hospital

Completed

Management of DE With IPL in Combination With DQS

Dry Eye

China
He Eye Hospital

Not yet recruiting

Temperature on Evaporative Dry Eye

Dry Eye

China
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Comparing Efficacy and Safety of TJO-083 in Dry Eye Disease Patients

Dry Eye Syndromes

Korea, Republic of
Yonsei University

Completed

Clinical Effects of Diquas-S for Patients With Dry Eye After Cataract Surgery

Dry Eye | Cataract Surgery

Korea, Republic of
Sylentis, S.A.

Completed

HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)

Dry Eye Disease

Spain, Portugal, Italy, Estonia, Germany, Slovakia
Santen Pharmaceutical Co., Ltd.

Completed

Study of DE-089 Ophthalmic Solution in Patients With Dry Eye

Dry Eye

Singapore, China
Aldeyra Therapeutics, Inc.

Completed

The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease

Dry Eye | Dry Eye Syndromes

United States
Hanlim Pharm. Co., Ltd.

Completed

A Clinical Trial to Evaluate Tolerability and Pharmacokinetics of HL217 Eye Drop in Healthy Male Subjects

Healthy Subject
Zhongshan Ophthalmic Center, Sun Yat-sen University

Recruiting

To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern

Dry Eye | Meibomian Gland Dysfunction

China
Yonsei University

Completed

Effect of ADDE on Tear Interferometry

Dry Eye Syndromes | Tear

Korea, Republic of
Mitotech, SA
ORA, Inc.

Completed

A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES)

Keratoconjunctivitis Sicca

United States
Merck Sharp & Dohme LLC

Terminated

Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642) (DEFY)

Cystic Fibrosis
Merck Sharp & Dohme LLC

Terminated

Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease

Cystic Fibrosis
Merck Sharp & Dohme LLC

Completed

A Study in Adult and Pediatric Patients With Cystic Fibrosis

Cystic Fibrosis
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease

Cystic Fibrosis

United States, Australia, Canada, New Zealand
Aldeyra Therapeutics, Inc.

Completed

ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Aldeyra Therapeutics, Inc.

Completed

A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Safety and Efficacy of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Syndrome

United States
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

Conjunctivitis, Allergic

Canada
Mimetogen Pharmaceuticals USA, Inc.

Completed

A Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye Syndromes

United States
Merck Sharp & Dohme LLC

Completed

A Safety and Tolerability Study of Denufosol in 2-4 Year Olds (REACH-1)

Cystic Fibrosis
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Rigel Pharmaceuticals

Completed

Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2) (DROPS-2)

Chronic Graft-versus-host Disease

United States
ORA, Inc.
Palatin Technologies, Inc

Completed

Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye

Dry Eye Disease

United States
Laboratorios Sophia S.A de C.V.

Withdrawn

Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis (PRO-118)

Conjunctivitis, Allergic | Seasonal Allergic Conjunctivitis | Ocular Itching | Ocular Allergy | Perennial Allergic Conjunctivitis

Mexico
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Mimetogen Pharmaceuticals USA, Inc.

Active, not recruiting

Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye Syndromes | Dry Eye Disease | Kerato Conjunctivitis Sicca

United States
Aldeyra Therapeutics, Inc.

Completed

A Clinical Trial to Assess Subjects With Dry Eye Disease.

Dry Eye

United States
Mimetogen Pharmaceuticals USA, Inc.

Completed

Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye

United States
Mimetogen Pharmaceuticals USA, Inc.

Completed

A Safety and Efficacy Study of Tavilermide (MIM-D3) Ophthalmic Solution for the Treatment of Dry Eye

Keratoconjunctivitis Sicca

United States
Aldeyra Therapeutics, Inc.

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease

Dry Eye Syndromes

Canada
Herantis Pharma Plc.
ORA, Inc.

Completed

Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye

Dry Eye Syndrome

United States
Aerie Pharmaceuticals

Completed

Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Rigel Pharmaceuticals

Completed

A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease

Keratoconjunctivitis Sicca

United States
OcuTerra Therapeutics, Inc.

Completed

Safety and Exploratory Efficacy Study of SF0166 for the Treatment of Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Aldeyra Therapeutics, Inc.

Completed

The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease

Dry Eye

United States
Aldeyra Therapeutics, Inc.

Completed

The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.

Allergic Conjunctivitis

Canada
Aerpio Therapeutics

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution

Primary Open Angle Glaucoma | Ocular Hypertension

United States

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