Search clinical trials for: Donepezil plus placebo

Total 58295 results

University Hospital, Lille
Innovative Medicines Initiative

Completed

Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development (PharmacogWP3)

Alzheimer Disease | Battery

France
Eisai Inc.

Completed

Safety, Tolerability, and Efficacy of Donepezil (Aricept) in Parkinson' s Disease (PD) Patients With Dementia

Parkinson's Disease | Dementia

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer
Pfizer

Completed

Study Evaluating The Coadministration of Begacestat And Donepezil

Healthy Subjects

United States
Pfizer

Terminated

Assessment Of The Effects Of Single Doses Of An Investigational Drug, Given Alone Or With Donepezil, On Scopolamine-Induced Changes In Memory And Learning In Healthy Adults

Healthy

United States
Ever Neuro Pharma GmbH
acromion GmbH

Completed

Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease (Combi)

Alzheimer Disease

Spain
Merck Sharp & Dohme LLC

Unknown

Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)

Mild Cognitive Impairment | Alzheimer's Disease
Eisai Co., Ltd.

Completed

A Double-blind Study of E2020 (Donepezil Hydrochloride) in Patients With Dementia With Lewy Bodies (DLB) (Study E2020-J081-431)

Dementia With Lewy Bodies (DLB)

Japan
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10

Cognitive Dysfunction | Down Syndrome

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17

Cognitive Dysfunction | Down Syndrome

United States
Eisai Co., Ltd.

Completed

A Study of E2020 in Patients With Dementia With Lewy Bodies (DLB), Followed by a Long-term Extension Phase

Dementia With Lewy Bodies (DLB)

Japan
Dongzhimen Hospital, Beijing

Completed

Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia

Vascular Dementia

China
Eisai Inc.

Completed

A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment

Mild Cognitive Impairment

United States
Pfizer

Completed

A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI

Alzheimer's Disease

United States
Shanghai Mental Health Center
The Davis Foundations

Completed

The Efficacy and Safety of AChE Inhibitor Donepezil As Adjunctive Treatment to Mood Stabilizers in Acute Mania

Bipolar Disorder | Mania
Eisai Co., Ltd.

Completed

A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease

Dementia Associated With Cerebrovascular Disease

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Study to Test the Performance of the CogState Computerized Neuropsychological Battery in Patients With Alzheimer's Disease (0000-086)(COMPLETED)

Alzheimer's Disease
VA Connecticut Healthcare System
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Yale University

Recruiting

Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

Alcohol Use Disorder

United States
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China
Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)

Dementia | Alzheimer's Disease
NYU Langone Health
Queens College, The City University of New York

Completed

Detecting an Early Response to Donepezil With Measures of Visual Attention

Alzheimer Disease

United States
Takeda

Terminated

Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants

Alzheimer Disease | Healthy Volunteers

United States
Mediforum Ltd., Co.
LSK Global Pharma Services Co. Ltd.

Recruiting

A Phase 2 Clinical Study to Explore the Optimal Dosage/Administration of PM012 Tablet in Alzheimer's Disease (PM012-2b)

Mild Alzheimer Disease

Korea, Republic of
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.

Cognitive Impairment | Radiation Injuries

China
Sanofi

Terminated

Effect on Cognitive Performance and Safety/Tolerability of SSR180711C in Mild Alzheimer's Disease

Alzheimer's Disease

France
National Institute on Aging (NIA)

Completed

Brain Imaging and Mental Disorders of Aging Intervention

Cognition Disorders

United States
Samsung Medical Center
Dong-A Pharmaceutical Co., Ltd.

Unknown

Zydena on Cognitive Function of Alzheimer's Disease Patients

Alzheimer's Disease

Korea, Republic of
Eisai Inc.
Eisai Limited

Completed

Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
AbbVie (prior sponsor, Abbott)

Completed

Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States, Poland, Russian Federation, South Africa, Ukraine, United Kingdom
Samsung Medical Center
Eisai Korea Inc.

Completed

Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia

Dementia | Alzheimer's Disease

Korea, Republic of
The Cleveland Clinic
National Institute on Aging (NIA)

Completed

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

Genetic Risk for Alzheimer's Disease

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease

Alzheimer's Disease

Russian Federation, South Africa, Ukraine, United Kingdom
Central South University

Unknown

A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia

Schizophrenia | Impaired Cognition

China
Corium, Inc.

Completed

A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®

Alzheimer Disease

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Brain Tumors | Metastatic Disease

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Enhancing Rehabilitation After Stroke (Enhance)

Ischemic Stroke

United States
Duke-NUS Graduate Medical School
GlaxoSmithKline

Completed

fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults

Sleep Deprivation

Singapore
Pfizer

Completed

A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes

Alzheimer Disease

Sweden
Beth Israel Deaconess Medical Center
National Institute on Aging (NIA)

Completed

Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period (SHARP)

Delirium

United States
Icure Pharmaceutical Inc.

Completed

A Phase I Clinical, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects

Alzheimer Disease

Korea, Republic of
Eisai Inc.
Pfizer

Completed

The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI)

Memory Loss

United States
Associacao Fundo de Incentivo a Psicofarmcologia
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Donepezil Treatment for Sleep Apnea Patients (doneapnea)

Obstructive Sleep Apnea

Brazil
Eisai Inc.

Completed

An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis

Migraine Headache

United States
Eisai Inc.
Pfizer

Completed

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

Down Syndrome

United States
Sunnybrook Health Sciences Centre
University of Toronto

Completed

Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults

Mental Health | Geriatrics

Canada
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Donepezil HCl & Cognitive Deficits in Autism

Autistic Disorder

United States
Merck Sharp & Dohme LLC

Completed

Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)

Dementia
Fundació Institut de Recerca de l'Hospital de la...

Not yet recruiting

Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease

Parkinson Disease | Mild Cognitive Impairment
University Hospital, Clermont-Ferrand
Federation Francophone de Cancerologie Digestive

Completed

Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study (DONEPEZOX)

Digestive Oncology | Supportive Care

France
Baylor College of Medicine
Albert Einstein Healthcare Network; Indiana University; Spaulding Rehabilitation... and other collaborators

Active, not recruiting

Multicenter Evaluation of Memory Remediation After TBI With Donepezil (MEMRI-TBI-D)

Traumatic Brain Injury | Memory Deficits

United States

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