Search clinical trials for: Doripenem or Piperacillin/Tazobactam

Total 127 results

Coordinación de Investigación en Salud, Mexico
Instituto Mexicano del Seguro Social; Hospital Infantil de Mexico Federico... and other collaborators

Completed

Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis

Sepsis

Mexico
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Rambam Health Care Campus
Hadassah Medical Organization; Rabin Medical Center; The Chaim Sheba Medical...

Suspended

PipEracillin/Tazobactam Versus mERoPENem for Treatment of AmpC Producing Blood Stream Infections (SPICE-M)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Fox Chase Cancer Center and other collaborators

Active, not recruiting

Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?

Pancreatic Cancer | Pancreatic Diseases | Pancreas Cancer

United States, Canada
The University of Queensland

Completed

Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response (MERINO II)

Bloodstream Infections

Singapore, Australia
University Ghent
King Baudouin Foundation; Belgische Vereniging voor Strijd tegen Mucoviscidose

Terminated

LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients

Cystic Fibrosis

Belgium
Allecra
Medpace, Inc.

Completed

Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections

Urinary Tract Infections

United States, Serbia, Hungary, Estonia, South Africa, Belarus, Poland, Ukraine, Argentina, Bulgaria, Croatia, Georgia, Latvia, Lithuania, Mexico, Peru, Russian Federation, Slovakia, Spain
Janssen Research & Development, LLC

Completed

A Crossover Study to Assess the Effect of Intravenous Infusion of Piperacillin/Tazobactam on the Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) in Healthy Adult Participants

Healthy

Belgium
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
Michael Cohen-Wolkowiez
The Emmes Company, LLC

Completed

Antibiotic Safety (SCAMP) (SCAMP)

Complicated Intra Abdominal Infections

United States, Canada
Memorial Sloan Kettering Cancer Center

Recruiting

Choosing the Best Antibiotic to Protect Friendly Gut Bacteria During the Course of Stem Cell Transplant

Febrile Neutropenia | Intestinal Microbiome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam

Other Infectious Diseases

United States
Ospedale San Carlo Borromeo
Associazione Oncologica Milanese AmoLaVita ONLUS

Not yet recruiting

Antibiotics Continuous Infusion at Home (TAID)

Severe Bacterial Infections

Italy
Tel-Aviv Sourasky Medical Center

Unknown

Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia (RR)

Fever | Febrile Neutropenia

Israel
Case Comprehensive Cancer Center

Recruiting

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Pancreatic Fistula

United States
Gruppo Italiano per la Valutazione degli Interventi...

Completed

AbioKin - Antibiotic Kinetics

Critical Illness | Infection

Italy
Melinta Therapeutics, Inc.

Withdrawn

A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (TANGOIII)

Hospital-Acquired Bacterial Pneumonia | Ventilator-Associated Bacterial Pneumonia | Hospital-Acquired Pneumonia | Ventilator-Associated Pneumonia
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Recruiting

Efficacy of Extended Infusion of β-lactam Antibiotics for the Treatment of Febrile Neutropenia in Hematologic Patients (BEATLE)

Febrile Neutropenia

Spain
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Vancomycin-Resistant Enterococci in a Hematology Unit

Gram-Positive Bacterial Infections

Korea, Republic of
Menarini Group

Terminated

Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections (DRESS)

Surgical Site Infection

Italy
McMaster Children's Hospital

Not yet recruiting

Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA) (ALPACA)

Appendicitis Perforated
Merck Sharp & Dohme LLC

Completed

Comparative Study of Ertapenem Versus Another Antibiotic in the Treatment of Diabetic Foot Infections in Adults (0826-034)

Foot Infections in Diabetic Patients
University Hospital Tuebingen

Terminated

Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion

Pneumonia | Bacteremia

Germany
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation

Completed

Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)

Sepsis | Acute Kidney Injury | Hemodiafiltration

Spain
Yuhan Corporation

Terminated

A Clinical Trial of YH1177 in Patients With Otitis Media and Otorrhea

Otitis Media | Otorrhea

Korea, Republic of
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

Safety and Efficacy of Vancomycin Plus Beta-lactams (SEVPB)

Critical Illness

China
Tri-Service General Hospital

Completed

A Single-Dose Pharmacokinetics Study of Tapimycin Injection

Healthy
Shandong University
Shandong Provincial Hospital

Recruiting

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

Early-Onset Neonatal Sepsis

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Fecal Transplant +/- Gut Decontamination in Preventing Acute Graft Versus Host Disease in Patients Given Broad-Spectrum Antibiotics

Graft-versus-host Disease Prevention

United States
Forest Laboratories

Terminated

Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With Cancer

Neoplasms | Febrile Neutropenia

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Chronic Obstructive Pulmonary Disease Trial Network...
Center for Genomic Medicine, Rigshospitalet, Denmark

Terminated

Targeted AntiBiotics for Chronic Pulmonary Diseases (Target-ABC)

Respiratory Tract Infections | Bronchiectasis | Asthma | COPD | Pseudomonas Aeruginosa

Denmark
Sanofi

Completed

Study to Demonstrate the Clinical Efficacy of Levofloxacin in the Treatment of Pneumonia

Pneumonia

France, Russian Federation, Spain, Italy, Belgium, Germany, Lebanon, Mexico, Venezuela, Czech Republic, Austria, South Africa, Turkey, Netherlands, Greece, Guatemala, Romania
Hospices Civils de Lyon

Recruiting

Observed Pharmacokinetic of Piperacillin/Tazobactam Compared to Amikacin in ICU (OPTIMA)

Sepsis | Septic Shock | Sepsis Syndrome

France
Zealand University Hospital

Recruiting

Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis. (PIPA)

Complicated Appendicitis

Denmark
Universitaire Ziekenhuizen KU Leuven

Unknown

Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients (TAPAS) (TAPAS)

Surgery

Belgium
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Tianjin Central Hospital of...

Recruiting

Antibiotic Therapy for Early Onset Neonatal Sepsis

Early Onset Neonatal Sepsis

China
Merck Sharp & Dohme LLC

Completed

Ertapenem Sodium vs. Piperacillin/Tazobactam in the Treatment of Complicated Intra-Abdominal Infections (0826-037)

Complicated Intra-Abdominal Infections
Duke University
Pediatric Pharmacology Research Units Network

Completed

Antimicrobial PK in Infants With Suspected or Confirmed Infection

Infection

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL) (A2B)

Burns Surgery

France
Mercy Health Ohio

Terminated

Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens

Open Fracture | Post-Op Wound Infection

United States
The Alfred

Unknown

A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cystic Fibrosis (CISTIC)

Cystic Fibrosis

Australia
University of Michigan

Completed

Optimal Care of Complicated Appendicitis

Appendicitis | Complicated Appendicitis | Perforated Appendicitis | Ruptured Appendicitis

United States
Assistance Publique - Hôpitaux de Paris

Completed

Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock (SSS)

Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit

France
The University of Queensland
Chinese University of Hong Kong; University of Malaya; The Alfred; Centre Hospitalier... and other collaborators

Recruiting

PNEUmonia DOSing in Critically Ill Patients (PNEUDOS) (PNEUDOS)

Pneumonia

Hong Kong, France, Belgium, Australia, Malaysia
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP

Acute Pyelonephritis | Urinary Tract Infection Complicated

Italy, Spain, Greece, Peru, United States, Bulgaria, Slovenia, Hungary, Romania, Brazil, Slovakia, Czechia, Ukraine, Taiwan, Belarus, Poland, Korea, Republic of
Sara Thønnings

Withdrawn

Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia

Bacteremia
University of Belgrade

Completed

Local and Systemic Antimicrobials in Non-surgical Periodontal Therapy

Periodontitis

Serbia

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