Search clinical trials for: drotrecogin alfa (activated)

Total 4376 results

GC Cell Corporation

Completed

Clinical Trial to Assess the Efficacy and Safety of 'INNOCELL Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea

Glioblastoma

Korea, Republic of
Mural Oncology, Inc

Recruiting

Nemvaleukin Alfa (ALKS 4230) Monotherapy in Patients With Advanced Cutaneous Melanoma or Advanced Mucosal Melanoma - ARTISTRY-6 (ARTISTRY-6)

Cutaneous Melanoma | Mucosal Melanoma

United States, Australia, Canada, Italy, Korea, Republic of, Spain, Taiwan, United Kingdom
University Hospital, Basel, Switzerland
University Hospital Freiburg; Istituto Ortopedico Galeazzi; General Hospital... and other collaborators

Completed

Clinical Trial for the Regeneration of Cartilage Lesions in the Knee (NosetoKnee2)

Tear; Knee, Cartilage, Articular

Switzerland, Germany, Croatia, Italy
Imperial College London
Medical University of Vienna; Queen's University, Belfast; Université d'Auvergne and other collaborators

Completed

Decision Support System to Evaluate VENTilation in ARDS (DeVENT)

Acute Respiratory Distress Syndrome

Austria, France, United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Study in Tissue Samples From Patients With Acute Myeloid Leukemia

Leukemia
Amgen

Terminated

Epoetin Alfa (EPO) in Subjects With Chronic Kidney Disease (CKD)

Chronic Kidney Disease
Dr. Behcet Uz Children's Hospital

Completed

Comparing Closed-loop FiO2 Controller With Conventional Control of FiO2

Acute Respiratory Failure | Acute Hypoxemic Respiratory Failure | Acute Hypoxemic and Hypercapnic Respiratory Failure

Turkey
Bruyere Research Institute
University of Ottawa

Completed

Adaptive Cognitive Training in Healthy Older Adults

Mild Cognitive Impairment | Alzheimer's Disease | Mild to Moderate Dementia

Canada
Denali Therapeutics Inc.

Recruiting

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (COMPASS)

Mucopolysaccharidosis II

United States, Spain, United Kingdom, Czechia, France, Canada, Italy, Belgium, Netherlands, Germany, Argentina, Sweden, Turkey, Colombia
National Cancer Institute (NCI)

Active, not recruiting

Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).

Olfactory Neuroblastoma | Esthesioneuroblastoma | Neoplasm of the Nasal Cavity

United States
Sanofi

Approved for marketing

Compassionate Use Program for Olipudase Alfa Enzyme Replacement Therapy for Patients With Chronic Acid Sphingomyelinase Deficiency (ASMD)

Sphingomyelin Lipidosis
Ari Zimran
Pfizer

Active, not recruiting

A Multicenter, Safety and Efficacy Study of Taliglucerase Alfa in Subjects With Type 3 Gaucher Disease

Gaucher Disease, Type 3

Israel, Turkey, India
Shire

Completed

Replagal Enzyme Replacement Therapy for Children With Fabry Disease

Fabry Disease

Canada, United States
Shire

Completed

Safety and Efficacy Study of Several Replagal Dosing Regimens on Cardiac Function in Adults With Fabry Disease

Fabry Disease

United States, United Kingdom, Australia, Czechia, Finland, Paraguay, Poland, Slovenia
Baylor Research Institute
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Dosing Study of Replagal in Patients With Fabry Disease

Fabry Disease

United States
Genzyme, a Sanofi Company

Completed

Extension Study of Long-term Safety and Efficacy of Myozyme in Patients With Pompe Disease Who Were Previously Enrolled in Genzyme Sponsored Enzyme Replacement Therapy (ERT) Studies

Glycogen Storage Disease Type II | Pompe Disease Infantile-Onset

United States, France, South Africa
Genzyme, a Sanofi Company

Approved for marketing

Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Infantile-onset Pompe Disease

Glycogen Storage Disease Type II | Glycogenosis 2
National Institute on Aging (NIA)

Completed

REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction

Acute ST Elevation Myocardial Infarction

United States
Janssen-Ortho Inc., Canada

Withdrawn

A Study to Determine an Effective Dose of Epoetin Alfa to Decrease the Number of Units of Blood Required to be Transfused During Hip Replacement Surgery.

Anemia | Blood Transfusion | Orthopedic Surgery
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Clinical Affairs, L.L.C.

Withdrawn

A Phase 2 Study to Evaluate the Safety and Effectiveness of Once Weekly or Once Every Two Week Dosing of Epoetin Alfa in Anemic Patients With Low- or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes | Anemia
Stanford University
National Institute on Aging (NIA)

Withdrawn

Erythropoietin Alfa in Elderly Subjects With Unexplained Anemia

Anemia

United States
University Medical Center Groningen
Janssen-Cilag Ltd.; The Interuniversity Cardiology Institute of the Netherlands

Completed

Clinical Study to Examine the Effects of Erythropoietin on Left Ventricular Function After Acute Myocardial Infarction (HEBEIII)

Myocardial Infarction

Netherlands
Spinal Missions, Inc., LLC

Completed

Measure the Effects of Specific Thoracic Chiropractic Adjustments on Blood Pressure and Pulse Rate

Hypertension
University Eye Hospital, Freiburg
German Federal Ministry of Education and Research

Completed

Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled Trial (TONE)

Optic Neuritis

Germany
Merck Sharp & Dohme LLC

Terminated

A Study of MK2578 in Patients With Chronic Kidney Disease Who Are Not on Dialysis (2578-002)

Anemia | Chronic Kidney Disease
European Organisation for Research and Treatment...
Charite University, Berlin, Germany; Trans Tasman Radiation Oncology Group; Groupe... and other collaborators

Terminated

Radiation Therapy With or Without Epoetin Alfa in Treating Patients With Head and Neck Cancer

Head and Neck Cancer

France, Belgium, Israel, United Kingdom, Australia, Spain, Germany, Switzerland, Hungary, Netherlands
Northwestern University
National Cancer Institute (NCI)

Completed

Exercise Plus Epoetin Alfa in Treating Cancer Patients Who Have Anemia-Related Fatigue

Fatigue | Anemia | Unspecified Adult Solid Tumor, Protocol Specific

United States
Washington University School of Medicine
National Institute of Neurological Disorders and Stroke (NINDS); PPD; Ortho Biotech...

Withdrawn

Epoetin Alfa for HIV-Associated Neuropathy Trial

HIV Infections | Neuropathy
Zydus Lifesciences Limited

Completed

Desidustat in the Treatment of Anemia in CKD (DREAM-ND)

Anemia | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

India
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo for the Treatment of Anemia in Patients With Acquired Immunodeficiency Syndrome (AIDS) Who Are Receiving Zidovudine (AZT) Therapy

Acquired Immunodeficiency Syndrome | Anemia
Federico II University

Completed

Efficacy of Epoetin Alfa in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Italy
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Biocad

Completed

An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients

Hepatitis | Hepatitis C | Hepatitis C/ Human Immunodeficiency Virus Coinfection

Russian Federation
Xiamen Amoytop Biotech Co., Ltd.
Peking University People's Hospital

Completed

Efficacy and Safety of Ypeginterferon Alfa-2b in Chronic Hepatitis C (PEGIFN)

Chronic Hepatitis C

China
Chiesi Farmaceutici S.p.A.

Not yet recruiting

Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3 (LAMPO(0-3))

Alpha-Mannosidosis
David L Rogers, MD

Active, not recruiting

Intravitreal ERT to Prevent Retinal Disease Progression in Children With CLN2

Neuronal Ceroid Lipofuscinosis Type 2

United States
Pfizer

Completed

Nonacog Alfa Prophylaxis And Treatment Of Bleeding Episodes In Previously Treated Patients With Hemophilia B

Hemophilia B

India
Genzyme, a Sanofi Company

Completed

Evaluate Efficacy and Safety in Chinese Patients With Infantile-Onset Pompe Disease With One Year Alglucosidase Alfa Treatment (APOLLO-IOPD)

Glycogen Storage Disease Type II

China
Genzyme, a Sanofi Company

Completed

Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease (PAPAYA)

Pompe Disease | Glycogen Storage Disease Type II (GSD II)

United States, Russian Federation, United Kingdom, Bulgaria, India, Ukraine
Shire

Completed

This Study is Designed to Evaluate PD/PK and Safety of Replagal Manufactured by Two Different Processes.

Fabry Disease

Canada
Shire
Quintiles, Inc.

Completed

Multicenter Extension Study of Velaglucerase Alfa in Japanese Patients With Gaucher Disease

Gaucher Disease

Japan
Chiesi Farmaceutici S.p.A.

Withdrawn

Interventional Study to Assess Efficacy and Safety of Velmanase Alfa in Patients With Alpha Mannosidosis (SHAMAN)

Alpha-Mannosidosis
JHL Biotech, Inc.

Completed

A Comparative Safety and Pharmacokinetic Study of JHL1922 and Pulmozyme® in Healthy Subjects

Healthy Subjects

Netherlands
Alexion Pharmaceuticals

Completed

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

Hypophosphatasia

United States, Germany
Genzyme, a Sanofi Company

Completed

rhGAA in Patients With Infantile-onset Glycogen Storage Disease-II (Pompe Disease)

Glycogen Storage Disease Type II | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease

United States, Israel, France, United Kingdom
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of rhGAA in Patients With Infantile-onset Pompe Disease

Glycogen Storage Disease Type II

United States, Taiwan, Israel, United Kingdom, France
Temple University

Unknown

Effectiveness of Manual Manipulation With EPAT on Ankle Dorsiflexion and Dynamic Plantar Pressure

Diabetes | Equinus Contracture of the Ankle

United States
AM-Pharma
FGK Clinical Research GmbH

Recruiting

Ilofotase Alfa for Prevention of Renal Damage After Cardiac Surgery

Open Heart Surgery

Germany
Alexion Pharmaceuticals, Inc.

Recruiting

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa (CHESTNUT)

Hypophosphatasia

United States, Japan, Italy, Germany, Turkey, India, Australia, United Kingdom, Argentina, France, Canada
Alexion

Recruiting

A Prospective Sub-Study of the Global Hypophosphatasia Registry

Hypophosphatasia

United States

Search clinical trials for: drotrecogin alfa (activated)

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