- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02205710
Adaptive Cognitive Training in Healthy Older Adults
July 31, 2019 updated by: Bruyere Research Institute
Cognitive training has emerged as a promising method to maintain, enhance, and rehabilitate cognitive function in older adults and individuals with dementia.
In recent years, such training has become particularly appealing in the clinical context, with many paradigms aimed specifically at adults experiencing various stages of cognitive decline due to Mild Cognitive Impairment, Alzheimer's disease, and vascular dementias.
However, basic questions remain.
For example, uncertainty persists regarding factors that influence observed improvements as well as the conditions that would maximize transfer and sustainability of training effects.
The objective of this study is to evaluate factors that may maximize the benefits of computerized cognitive training in older adults.
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
The study involves 25 sessions of an adaptive cognitive training program, completed over 5 weeks.
Pre and post training assessments will evaluate any near and far transfer effects of training.
Study Type
Interventional
Enrollment (Actual)
99
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Ontario
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Ottawa, Ontario, Canada, K1N 5C8
- Bruyere Continuing Care
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
60 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- English as the maternal or primary spoken language.
- Good self-reported health (i.e., no cerebro-, or cardio-vascular disease or neurological disease).
- Normal or corrected-to-normal vision and hearing.
Exclusion Criteria:
- Poor hearing or vision
- Inadequate understanding of the English language
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Triple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Computerized cognitive training
Series of gamified tasks.
|
Other Names:
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Placebo Comparator: Computerized game training
Series of gamified tasks.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Change in ratings on cognitive training survey
Time Frame: Baseline, week 5
|
This survey aims to assess participant perceptions on cognitive training, and includes a series of related questions, rated on a scale of 1-7.
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Baseline, week 5
|
Change in neural activity
Time Frame: Baseline, week 5
|
We will measure resting state as well as task-related EEG responses to determine the effects of cognitive training at the neural level.
|
Baseline, week 5
|
Change in performance on neuropsychological tests
Time Frame: Baseline, week 5
|
Using a set of standard neuropsychological evaluations, we will measure changes in attention, memory, and executive function following cognitive training.
|
Baseline, week 5
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Change in ratings of psychological wellbeing
Time Frame: Baseline, week 5
|
We will use standardized questionnaires to assess quality of life, in order to measure the influence of cognitive training on factors related to wellbeing.
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Baseline, week 5
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Patrick Davidson, PhD, University of Ottawa
- Study Director: Sheida Rabipour, MSc, University of Ottawa
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2016
Primary Completion (Actual)
August 1, 2018
Study Completion (Actual)
August 1, 2018
Study Registration Dates
First Submitted
July 29, 2014
First Submitted That Met QC Criteria
July 30, 2014
First Posted (Estimate)
July 31, 2014
Study Record Updates
Last Update Posted (Actual)
August 2, 2019
Last Update Submitted That Met QC Criteria
July 31, 2019
Last Verified
August 1, 2017
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- M16-14-018
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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