Search clinical trials for: EKB-569

Total 705 results

Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; University of Bern

Recruiting

Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma (MACOCUC-01)

Advanced Urothelial Carcinoma

Switzerland
Otto-von-Guericke University Magdeburg

Completed

Lung Isolation in Thoracic Surgery - a Randomized Trial Comparing the VivaSight™ EB Endobronchial Blocker With Established Devices

One-Lung Ventilation | Lung Separation Techniques
Shanghai Public Health Clinical Center
Zhejiang University; Yunnan Provincial Infectious Disease Hospital; Shenzhen... and other collaborators

Unknown

Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With Tuberculosis (RRHT)

Tuberculosis, Pulmonary | AIDS

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | ERBB2 Gene Amplification | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon Cancer AJCC v7 | Stage... and other conditions

United States, Puerto Rico
University of Washington
National Cancer Institute (NCI); National Center for Complementary and Integrative...

Completed

Vaccine Therapy With or Without Polysaccharide-K in Patients With Stage IV HER2 Positive Breast Cancer Receiving HER2-Targeted Monoclonal Antibody Therapy

Stage IV Breast Cancer | Recurrent Breast Carcinoma | HER2/Neu Positive

United States
AVIR Green Hills Biotechnology AG

Completed

Dose Finding Study of Single Dose GHB11L1 in Healthy Adults (GHB-CS07)

Influenza, Human

Austria
Bayer
Janssen Research & Development, LLC

Completed

Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on the Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 15 mg in Japanese Healthy Male Adult Subjects

Clinical Pharmacology

Japan
Case Comprehensive Cancer Center

Completed

Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer

Prostate Cancer

United States
The University of Texas Health Science Center,...
Janssen Scientific Affairs, LLC

Withdrawn

Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer

Prostate Cancer

United States
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Withdrawn

Immunogenicity and Safety of COVID-19 Vaccine in Population Aged 18 Years and Above

COVID-19

China
Fukushima Medical University
Human Genome Center, Institute of Medical Science, University of Tokyo

Unknown

Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer

Pancreatic Cancer

Japan
4th Military Hospital

Recruiting

Incidence and Duration of Unintentional Neuromodulation Effects After Pulmonary Vein Isolation in Patients With Atrial Fibrillation. (UNCOVER-PVI)

Atrial Fibrillation

Poland
University of Pittsburgh
Novartis Pharmaceuticals

Terminated

Pemetrexed and LBH589 in Patients With Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Tucatinib Combined With Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Completed

Paclitaxel and Radiation Therapy With or Without Trastuzumab in Treating Patients Who Have Undergone Surgery for Bladder Cancer

Bladder Urothelial Carcinoma | Stage I Bladder Cancer AJCC v6 and v7 | Stage II Bladder Cancer AJCC v6 and v7 | Stage III Bladder Cancer AJCC v6 and v7

United States, Canada
Eye & ENT Hospital of Fudan University

Not yet recruiting

Different Dosing Regimens of STOP-AST

Hearing Loss | Sensorineural Hearing Loss | Tinnitus
University of California, Davis
Novartis Pharmaceuticals

Completed

Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors

Solid Tumors | Non-Small Cell Lung Cancer (NSCLC)

United States
Bayer
Janssen Research & Development, LLC

Completed

Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 10 mg in Japanese Healthy Male Adult Subjects

Clinical Pharmacology

Japan
Cancer Institute WIA

Completed

Use of Interim PET Scan to Modify Therapy in Advanced Hodgkin's Lymphoma in Order to Improve Outcomes

Hodgkin's Lymphoma

India
Fukushima Medical University
Human Genome Center, Institute of Medical Science, University of Tokyo

Completed

Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)

Pancreatic Cancer

Japan
Wakayama Medical University
Human Genome Center, Institute of Medical Science, University of Tokyo

Completed

Gemcitabine With Antiangiogenic Peptide Vaccine Therapy in Patients With Pancreatic Cancer

Pancreatic Cancer

Japan
National Cancer Institute (NCI)

Completed

Trastuzumab and Gefitinib in Treating Patients With Metastatic Breast Cancer

Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Fluart Innovative Vaccine Ltd, Hungary

Completed

Tolerability and Immunogenicity Study of FLUVAL P H1N1 Flu Vaccine of Omninvest in Children and Adolescents

Influenza, Human | Novel 2009 Influenza H1N1

Hungary
Imperial College London
Institute of Neuroscience and Medicine, Julich, Germany

Withdrawn

Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment. (AldoSalt)

Hypertension | Hyperaldosteronism; Primary | Salt; Excess | Appetite Disorders

United Kingdom
Wake Forest University Health Sciences

Recruiting

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Tibial Fractures | Osteomyelitis Tibia | Open Tibia Fracture

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

BAY 56-3722 in Treating Patients With Recurrent, Unresectable, or Metastatic Kidney Cancer

Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Hypophosphatasia (HPP)

United States, Canada, United Arab Emirates, United Kingdom
Bayer

Completed

Evaluation of Bay 59-8862 in Patients With Advanced Renal Cell Carcinoma

Carcinoma, Renal Cell

Canada, United States, Germany, United Kingdom, France, Netherlands
George E. Peoples
Genentech, Inc.; Sellas Life Sciences Group

Completed

Combination Immunotherapy With Herceptin and the HER2 Vaccine NeuVax

Breast Cancer

United States
Sindh Institute of Urology and Transplantation

Completed

Comparison Between Sevoflurane and Propofol for Maintenance of Sedation During ERCP

Sedation Complication

Pakistan
Johns Hopkins University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Optimizing Treatment to Improve TBM Outcomes in Children (TBM-KIDS)

Tuberculosis, Meningeal

India, Malawi
University of Washington
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride Liposome, Cyclophosphamide, and Trastuzumab in Treating Patients With Stage IV Breast Cancer

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Boston University

Completed

Safety and Effect of Doxycycline in Patients With Amyloidosis

Amyloidosis

United States
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
National Cancer Institute, Egypt

Completed

Serratus Anterior Block and Erector Spinae Block in Postoperative Analgesia

Postoperative Analgesia

Egypt
Bausch & Lomb Incorporated

Completed

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic Conjunctivitis

Seasonal Allergic Conjunctivitis

United States
VA Office of Research and Development

Completed

Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer

Newly Diagnosed Oligometastatic Prostate Cancer

United States
Changhua Christian Hospital

Completed

Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas

Type 2 Diabetes Mellitus | Proteinuria
Texas Tech University
American Egg Board

Completed

High Quality Protein for Assisting With Weight Loss (Egg_breakfast)

Obesity

United States
Texas Tech University
American Egg Board

Completed

Breakfast Intake and Satiety Hormones

Obesity

United States
University of Nebraska
National Cancer Institute (NCI)

Active, not recruiting

Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After Surgery

HER2 Positive Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Ipsen

Completed

Effect of 120mg Somatuline Autogel at Different Dose Intervals (28, 42 or 56 Days) in Patients With Acromegaly

Acromegaly

Germany
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) for Recurrent, Metastatic, or Unresectable HER2-Positive Salivary Gland Cancer

Recurrent Salivary Gland Carcinoma | Stage III Major Salivary Gland Cancer AJCC v8 | Stage IV Major Salivary Gland Cancer AJCC v8 | Metastatic Salivary Gland Carcinoma | Unresectable Salivary Gland Carcinoma

United States
Akebia Therapeutics

Completed

Effect of AKB-6548 on the Pharmacokinetics of Celecoxib

Healthy Volunteers
National Cancer Institute (NCI)

Terminated

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIC Breast Cancer | Adenocarcinoma of the Gastroesophageal Junction | Recurrent Breast Cancer | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Stage IIIC Gastric... and other conditions

United States
Unity Health Toronto
CIHR Canadian HIV Trials Network

Completed

Bone Antiresorptive Therapy With Antiretroviral Initiation (BATARI) Pilot Trial (BATARI)

HIV

Canada
Centre for Food and Nutrition Research, Yaounde
International Atomic Energy Agency

Completed

Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition

Wasting | Moderate Acute Malnutrition

Cameroon
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Netherlands, United Kingdom, Germany, Portugal
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States

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