Search clinical trials for: ET-1 Inhibition Placebo

Total 3569 results

EMD Serono

Terminated

Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis

Arthritis, Psoriatic

United States, Canada
Alexion Pharmaceuticals, Inc.

Completed

Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)

Paroxysmal Nocturnal Hemoglobinuria

France, Italy, Spain, United States, Taiwan, Thailand, Korea, Republic of, Japan, Malaysia, Brazil, Germany, Israel, Czechia, Netherlands, Greece, United Kingdom, Canada, Poland
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Oryn Therapeutics, LLC

Completed

Randomized, Double-blind, Vehicle Controlled, Repeat Dose Comparative Study in RA Patients Managed With DMARDs

Rheumatoid Arthritis

United States
Medical University of Vienna

Completed

Mechanisms of Human Heat Perception - Involvement of TRPA1, TRPV1 and TRPM3

Pain

Austria
International AIDS Vaccine Initiative
Coalition for Epidemic Preparedness Innovations

Recruiting

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

Lassa Fever

Ghana, Liberia, Nigeria
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) (APECS)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment | Prodromal Alzheimer's Disease
Mayo Clinic

Recruiting

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia

Recurrent Chronic Myelomonocytic Leukemia | Refractory Chronic Myelomonocytic Leukemia

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris (OREA)

Acne Vulgaris | Acne

Germany
AbViro LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study to Determine the Safety of AV-1, an Antibody Being Developed for Treatment of Dengue, in Healthy Volunteers

Healthy Volunteers

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States
InnoSportNL
Avebe U.A.

Completed

A Low-osmolaric Glucose Polymer Drink for Gastric Distress and Running Performance

Gastric Distress | Running Performance

Netherlands
UCB Pharma
Parexel

Completed

Study to Assess Safety, Tolerability, Pharmacokinetic & Pharmacodynamic Effect of UCB5857 in Healthy & Psoriatic Subject

Psoriasis

United Kingdom
Stallergenes Greer
Quintiles, Inc.

Completed

Safety, Tolerability and Pharmacodynamic Effects of Sublingual Immunotherapy (Tablets) With Recombinant Bet v1

Rhinitis, Allergic, Seasonal | Birch Pollen-Related Rhinoconjunctivitis

Denmark
Metropolitan University, Serbia

Completed

Guanidinoacetic Acid (GAA) Administration in Physically Active Men and Women

Athletic Performance

Serbia
Assistance Publique - Hôpitaux de Paris

Completed

Bee Venom for the Treatment of Parkinson Disease (MIREILLE)

Parkinson Disease

France
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Novozymes A/S
Analyze & Realize

Not yet recruiting

Effect of a Combination of Lactase and L. Salivarius DSM 34078 in Individuals With Lactose Intolerance

Lactose Intolerance
Azienda Ospedaliera Universitaria Integrata Verona
Azienda Ospedaliera di Padova; University of Milan; Università degli Studi di...

Completed

Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE (MAYBE)

Frailty | Sarcopenic Obesity | Malnutrition; Protein

Italy
Glia, LLC

Active, not recruiting

Safety and Efficacy of Pro-ocular™ 1% in Daily Scleral Lens Wearing Patients With Ocular Graft-versus-Host Disease

Ocular Graft-versus-host Disease

United States
OxThera

Completed

A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

Primary Hyperoxaluria

France, United Kingdom, Spain, Belgium, United States, Germany, Tunisia
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States
Brock Beauty Inc.
KGK Science Inc.

Completed

A Clinical Trial to Evaluate the Effectiveness of Hairfinity on Improving Hair Health and Rate of Growth

Healthy Participants

Canada
Laboratoires Besins International

Unknown

Testogel® (Testosterone Gel 50mg/5g) in the Treatment of Male Hypogonadism

Hypogonadism

China
AJU Pharm Co., Ltd.
GL Pharm Tech Corporation

Completed

Efficacy and Safety of AJU-S56 in Dry Eye Syndrome Patients

Dry Eye Syndromes

Korea, Republic of
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Tetherex Pharmaceuticals Corporation

Completed

Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2)

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Kamada, Ltd.
Syneos Health

Recruiting

Evaluate Efficacy and Safety of "Kamada-AAT for Inhalation" in Patients With AATD (InnovAATe)

Alpha 1-Antitrypsin Deficiency

United Kingdom, Sweden, Ireland, Netherlands, Belgium, Finland
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, United Kingdom, Spain, Germany, Australia, Canada, Puerto Rico, Bulgaria, Poland, Romania
Curadel Surgical Innovations, Inc.
Erasmus Medical Center; Leiden University Medical Center

Recruiting

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery (TRIPHASE)

Injury of Ureter During Surgery (Disorder)

Netherlands
Seppic

Completed

Evaluation of the Anti-aging Efficacy of Two Dietary Supplements

Healthy Volunteers

Italy
Arthrosi Therapeutics

Completed

Phase 2b Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, Taiwan
InflaRx GmbH

Completed

Studying Complement Inhibition in Complex Cardiac Surgery (CARDIAC)

Systemic Inflammatory Response Syndrome | C.Surgical Procedure; Cardiac

Germany
Erchonia Corporation

Terminated

Study of Low Level Laser Therapy and Tinnitus Relief

Tinnitus

United States
Stallergenes Greer
Quintiles, Inc.

Completed

Safety and Tolerability Study of rBet v1 SLIT Tablets

Rhinitis, Allergic, Seasonal | Birch Pollen-Related Rhinoconjunctivitis

Denmark
SK Chemicals Co., Ltd.

Completed

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of SKI2670

Endometriosis

Korea, Republic of
Grifols Therapeutics LLC

Terminated

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Depression

China
Chongqing Medical University

Not yet recruiting

The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEF (ARNICFH)

Heart Failure With Preserved Ejection Fraction

China
Second Affiliated Hospital, School of Medicine,...
Zhejiang Cancer Hospital; Sun Yat-sen University; Ningbo Medical Center Lihuili... and other collaborators

Recruiting

Multi-center Observational Study on the Progression of Atherosclerotic Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Plaque, Atherosclerotic | Programmed Cell Death Protein 1 Inhibitor

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)

Graft-Versus-Host Disease (GVHD) Acute on Chronic

United States
KK Women's and Children's Hospital

Completed

Study of Dehydroepiandrosterone Treatment for Poor Responders in In Vitro Fertilization Patients

Infertility | Poor Responder to IVF Treatment

Singapore
Nestlé
Institut National de la Recherche Agronomique; Centre de Recherche en Nutrition...

Completed

Effects of Hesperidin on Bone Mineral Density and Bone Metabolism of Postmenopausal Women

Osteoporosis, Osteopenia

France
George Stavroulakis
Odense University Hospital; Medical University of Lodz; National and Kapodistrian... and other collaborators

Completed

FAST Fish Phase IIb Clinical Trial for the Treatment of Fish Allergy by Subcutaneous Immunotherapy (FASTIIb)

Food Allergy to Fish

Denmark, Greece, Iceland, Netherlands, Poland, Spain
Novartis Pharmaceuticals

Withdrawn

A Study to Evaluate the Effects of Indacaterol Maleate (QAB149) as a New Formulation in the EPIC Test Fixture

Asthma
Government Dental College and Research Institute...

Completed

1% Metformin in Moderate and Severe Periodontitis

Periodontitis
Aronora, Inc.

Completed

Safety and Efficacy Study of AB023 (Xisomab 3G3) in End Stage Renal Disease Patients on Chronic Hemodialysis

Thrombosis | End Stage Renal Disease

United States
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease (SynCeD)

Celiac Disease | Coeliac Disease

United States, Canada, Poland, Germany
SecuraBio

Completed

A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects

Asthma

Germany, United Kingdom

Search clinical trials for: ET-1 Inhibition Placebo

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