Search clinical trials for: Early Management

Total 5176 results

Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, First-in-human Study of VX-828

Cystic Fibrosis

United States
Nicole Fram M.D.

Completed

Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery

Intraocular Pressure | Anterior Chamber Inflammation | Ocular Pain | Corneal Edema | Corneal Defect | Penetrating KeratoPlasty | Corneal Transplant

United States
Boehringer Ingelheim

Completed

Observational Study of Adherence to LABA / LAMA in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany
TC Erciyes University

Completed

Controlled Hypotension During Functional Endoscopic Sinus Surgery

Hemorrhage
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Usama Azhar
King Edward Medical University

Recruiting

Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age

Allergic Rhinitis

Pakistan
Ohio University
GlaxoSmithKline; Merck Sharp & Dohme LLC; National Institute of Neurological...

Completed

Drug and Non-Drug Treatment Of Severe Migraine (TSM)

Migraine Headache

United States
Soroka University Medical Center

Completed

Sequential Therapy Versus Quadruple Therapy as Second Line Treatment After Failure of the Standard Triple Therapy for H Pylori Infection

Optimization of Second Line Treatment Protocol for H Pylori Eradication

Israel
University of Southern California
National Cancer Institute (NCI)

Terminated

Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.

Lymphedema | Stage II Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Recurrent Breast Cancer

United States
Stony Brook University
National Institute of Mental Health (NIMH)

Completed

Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity Disorder

Conduct Disorder | Oppositional Defiant Disorder | Attention Deficit Disorder With Hyperactivity

United States
University of Cincinnati

Completed

Belatacept Early Steroid Withdrawal Trial

Renal Transplantation

United States
R.J. Reynolds Vapor Company
Covance; R.J. Reynolds Tobacco Company; MAS (Materials Analytical Services), LLC

Completed

Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes

Smoking

United States
Shanghai Zhongshan Hospital

Unknown

Multimodal Analgesia Versus Traditional Opiate Based Analgesia

Cardiac Surgery
Gilead Sciences

Completed

Safety and Efficacy of Cobicistat-boosted Atazanavir Compared to Ritonavir-boosted Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Single Doses of Dabigatran Etexilate in Healthy Volunteers

Healthy
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia

Leukemia

United States
Marco Valgimigli

Unknown

Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI

Myocardial Infarction

Italy
University of California, San Diego

Active, not recruiting

Comparing Perioperative Outcomes in Pain Control

Post-operative Pain

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Comparing Smoking Treatment Programs for Lighter Smokers - 1

Tobacco Use Disorder

United States
Yale University
National Cancer Institute (NCI)

Active, not recruiting

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV (SMARTTT)

Tobacco Use Cessation

United States
Mayo Clinic

Withdrawn

A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation

Head and Neck Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions
Seoul National University Hospital
National Institute of Food and Drug Safety Evaluation, Korea

Completed

Cytochrome P450 2D6 Genotype on the Clinical Effect of Carvedilol

Healthy

Korea, Republic of
Boehringer Ingelheim

Completed

Drug-interaction Trial in Healthy Subjects With Oral Administration of Empagliflozin (BI 10773), Rifampicin and Probenecid

Healthy

Germany
Assiut University

Not yet recruiting

Impact of Blood Culture Positivity Time on Clinical Management of Pediatric ICU Patients

Sepsis

Egypt
McGill University Health Centre/Research Institute...
GlaxoSmithKline

Completed

Strategy for Early Treatment of Exacerbations in COPD: Standing Prescriptions of Advair With a Written Action Plan in the Event of an Exacerbation

Chronic Obstructive Pulmonary Disease | COPD

Canada
University of Missouri-Columbia

Recruiting

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) (CATBITE)

Infection, Bacterial | Anti-bacterial Agents | Hand Injuries | Arm Injury | Cat Bite

United States
Sahlgren´s University Hospital
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden

Completed

Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma

Trauma | Surgery | Flail Chest | Rib Fractures

Sweden
Dong-A University

Completed

Long-term Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy for Treatment of Lower Extremity Bowen's Disease

Bowen's Disease
Nexgen Pharma, Inc
Pharmaceutical Research Unit, Jordan

Completed

Codeine Phosphate/Guaifenesin ER Tablet 30 mg/600 mg Steady State Clinical Study (COGUSS)

Cough

Jordan
University of Rochester

Completed

Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy

Polycystic Ovary Syndrome

United States
Ain Shams University

Not yet recruiting

Efficacy of Adding Dexmedetomidine Versus Ibuprofen as an Adjuvant to Intraperitoneal Bupivacaine for Pain Control After Laparoscopic Gynecological Procedures

Postoperative Pain, Acute
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Not yet recruiting

Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis (AA-ICAS)

Ischemic Stroke | Stenosis | Intracranial Atherosclerosis
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
Duke University

Completed

Mobile Contingency Management for Marijuana and Tobacco Cessation

Marijuana Abuse | Cigarette Smoking

United States
AstraZeneca

Completed

Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) (ECLIPSEIII)

Hypertriglyceridemia

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Abiraterone in Healthy Male Participants

Healthy

Belgium
European Organisation for Research and Treatment...

Terminated

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Fever, Sweats, and Hot Flashes | Myelodysplastic/Myeloproliferative Neoplasms

France, Switzerland, Belgium, Germany, Italy, Israel, Slovakia, Turkey
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
National Cancer Institute (NCI)

Active, not recruiting

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Invasive Breast Carcinoma | Triple-Negative Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage 0 Breast Cancer AJCC v6 and v7

United States, Canada, Puerto Rico
Ascletis Pharmaceuticals Co., Ltd.

Completed

Study to Evaluate the Effects of Itraconazole and Rifampin on the Pharmacokinetics of ASC40 in Healthy Subjects

Healthy

China
Duke University

Completed

Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)

Smoking

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer

Lymphoma | Leukemia

United States
Duke University
Durham VA Medical Center

Completed

Contingency Management for Smoking Cessation in Homeless Smokers

Smoking | Homeless Persons

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Smoking Interventions for Hospital Patients (Helping HAND)

Cigarette Smoking

United States
Agency for Healthcare Research and Quality (AHRQ)

Completed

Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network (VCAT)

Vaginitis

United States
Pfizer

Completed

Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®)

Tuberculosis

Philippines
University Hospital, Strasbourg, France
Institut National de la Santé Et de la Recherche Médicale, France; Service... and other collaborators

Terminated

Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy

Heart Failure

France
Central Hospital, Nancy, France

Recruiting

FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort

Cardiovascular Diseases | Risk Factors | Nutrition | Cohort Studies | Genotype

France
University of Virginia

Recruiting

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

Smoking | Smoking Cessation | Smoking Reduction | Smoking, Tobacco | Smoking, Cigarette | Quitting Smoking

United States
University of Sao Paulo General Hospital

Completed

Magnesium Sulfate Versus Dexmedetomidine on Anesthesia Awakening.

Cholecystectomy

Brazil

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