Search clinical trials for: Eculizumab Injection

Total 9836 results

Marmara University
National Institute of Allergy and Infectious Diseases (NIAID)

Unknown

Transcriptome and Metabolic Analyses of CHAPLE Disease (CHAPLEOMIC)

Protein-Losing Enteropathies | CD55 - Cluster of Differentiation Antigen 55 Deficiency | Primary Intestinal Lymphangiectasis | Complement Regulatory Factor Defect

Turkey
Russian Academy of Medical Sciences

Completed

Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury

End-Stage Renal Disease | Kidney Failure | Graft Reperfusion Injury

Russian Federation
Samsung Bioepis Co., Ltd.

Completed

A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Korea, Republic of, Taiwan, Malaysia, Thailand, Romania, India, Mexico, Ukraine
Uppsala University

Completed

Complement Inhibitor Eculizumab in Clinical Islet Transplantation (ICC)

Diabetes Mellitus

Sweden
Alexion

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Netherlands, Sweden, Italy
Alexion Pharmaceuticals

Completed

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Hemoglobinuria, Paroxysmal

United States, Australia, Belgium, Canada, Germany, Italy, United Kingdom, France, Ireland, Netherlands, Sweden, Switzerland
Turgut Ardika PTY LTD

Recruiting

Comparative PK, Safety, Tolerability, Immunogenicity, and PD Profile Study of TUR03 and Soliris in Healthy Participants

Healthy

Australia
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
Nantes University Hospital

Completed

Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS (STOPECU)

Atypical Hemolytic Uremic Syndrome

France
Alexion

Approved for marketing

The Paroxysmal Nocturnal Hemoglobinuria Early Access Treatment Protocol (EMBRACE)

Hemoglobinuria, Paroxysmal

United States
Alexion

Completed

Safety and Efficacy Study of Eculizumab in Patients With Mild Allergic Asthma

Allergic Asthma

Canada
Alexion Pharmaceuticals

Terminated

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

United States, Canada, United Kingdom
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS) (STEC-HUS)

Shiga-like Toxin-producing Escherichia Coli

Germany
Alexion Pharmaceuticals

Completed

An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorder

Hong Kong, Korea, Republic of, United States, Croatia, Australia, Canada, Malaysia, Japan, Italy, Turkey, Spain, Taiwan, Argentina, Colombia, Czechia, Denmark, Germany, Russian Federation, Thailand, United Kingdom
Alexion Pharmaceuticals

No longer available

SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19

COVID-19 | Pneumonia, Viral | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States, France
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS) (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Sweden, Netherlands, Italy
Alexion Pharmaceuticals

Completed

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Hemoglobinuria, Paroxysmal

United States, United Kingdom, Australia, Belgium, Canada, France, Germany, Ireland, Italy, Netherlands, Spain, Sweden, Switzerland
Alexion Pharmaceuticals

Completed

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Hemoglobinuria, Nocturnal

United States, Australia, Belgium, Canada, Germany, Italy, Spain, Sweden, United Kingdom, France, Ireland, Netherlands
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Alexion...

Withdrawn

Eculizumab Therapy for Subclinical Antibody-mediated Rejection in Kidney Transplantation (TAMARCIN)

Subclinical Acute Antibody-mediated Rejection in Kidney Transplantation
Biocad

Completed

Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris®

Healthy Subjects

Russian Federation
AO GENERIUM

Completed

Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria | Marchiafava-Micheli Syndrome | Paroxysmal Hemoglobinuria

Russian Federation
Weill Medical College of Cornell University

Completed

Identification and Treatment of Thrombotic Microangiopathies in Allogeneic Stem Cell Transplants

Thrombotic Microangiopathy | Disorder Related to Bone Marrow Transplantation

United States
University Hospital, Tours
Hospices Civils de Lyon; University Hospital, Strasbourg, France; University... and other collaborators

Active, not recruiting

Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU) (EspacECU)

Hemolytic-Uremic Syndrome, Atypical

France
Genentech, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Plaque Psoriasis Involving the Hands and/or Feet

Psoriasis
Merck KGaA, Darmstadt, Germany

Completed

Efalizumab for Treatment of Patients With Moderate to Severe Psoriasis

Moderate to Severe Psoriasis

Switzerland
Genentech, Inc.

Completed

A Study to Evaluate Raptiva in Subjects With Chronic Moderate or Worse Plaque Psoriasis Who Have Had an Inadequate Response to an Anti-TNF Agent

Psoriasis
Genentech, Inc.

Completed

A Study to Evaluate Efalizumab in Adults With Plaque Psoriasis, Including Those Who Are Receiving Concomitant Antipsoriatic Therapies

Psoriasis
Norwegian University of Science and Technology

Terminated

Classification and Characterization of Patients Treated With Efalizumab for Plaque Psoriasis

Plaque Psoriasis

Norway
Washington University School of Medicine
Genentech, Inc.

Completed

Safety and Effectiveness of Efalizumab to Treat Oral Lichen Planus

Lichen Planus, Oral

United States
NYU Langone Health
Genentech, Inc.

Completed

Efficacy and Safety of Efalizumab in the Treatment of Moderate-Severe Hydradenitis Suppurativa

Hidradenitis Suppurativa

United States
University Hospital, Rouen

Not yet recruiting

Multicenter, Uncontrolled Pilot Study Evaluating the Efficacy of Eculizumab in the Treatment of Gemcitabine-induced Thrombotic Microangiopathies (GEMECULI)

Thrombotic Microangiopathies

France
Rockefeller University
Genentech, Inc.

Completed

Study of the Drug Efalizumab (Raptiva), for Adult Patients With Moderate to Severe Plaque Psoriasis

Psoriasis

United States
The Cleveland Clinic

Withdrawn

Discoid Lupus Erythematosus of the Scalp and a Trial of Biologic Therapy With Raptiva

Discoid Lupus Erthematosus of the Scalp

United States
Genentech, Inc.

Completed

A Study to Evaluate the Safety of Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2600g

Psoriasis
Genentech, Inc.

Completed

A Study to Evaluate Raptiva in Adults With Moderate to Severe Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis
Oregon Health and Science University

Completed

Efalizumab for Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic
Genentech, Inc.

Completed

A Study to Evaluate Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2390g

Psoriasis
Genentech, Inc.

Completed

A Study to Evaluate Raptiva in Combination With Topical Psoriasis Therapies

Psoriasis
Radboud University Medical Center

Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

Paroxysmal Nocturnal Hemoglobinuria | Eculizumab | PK-PD

Netherlands
AO GENERIUM

Completed

A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation) (NAP)

Paroxysmal Nocturnal Hemoglobinuria

Russian Federation
Jonsson Comprehensive Cancer Center

Completed

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

Leukemia

United States
Merck KGaA, Darmstadt, Germany

Completed

A Multicentre, Open Label Phase IIIb/IV Study of Subcutaneously Administered Raptiva in the Treatment of Adult Subjects With Moderate to Severe Plaque Psoriasis

Psoriasis | Candidates for Systemic Therapy for Psoriasis

Switzerland
Northwestern University
Genentech, Inc.

Withdrawn

Efalizumab in the Treatment of Alopecia, Phase II

Alopecia Totalis
University of Medicine and Dentistry of New Jersey
Genentech, Inc.

Completed

Efalizumab for Eczema

Dermatitis, Atopic

United States
Genentech, Inc.

Completed

A Study to Evaluate the Effects of Efalizumab on Immune Responses in Subjects With Moderate Plaque Psoriasis

Plaque Psoriasis
Genentech, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Moderate to Severe Plaque Psoriasis With Involvement of the Scalp (SCALP)

Psoriasis
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
Sanjay Kulkarni
Alexion Pharmaceuticals

Completed

Eculizumab Therapy for Chronic Complement-Mediated Injury in Kidney Transplantation

Kidney; Complications, Allograft

United States
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention (IA)

HIV Infections

United States

Search clinical trials for: Eculizumab Injection

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