Search clinical trials for: Eloctate ITI

Total 4470 results

Margaret Ragni

Withdrawn

Hemophilia Inhibitor Clinical Trials (INHIBIT) Platform (INHIBIT)

Severe Hemophilia A

United States
Margaret Ragni
Health Resources and Services Administration (HRSA)

Terminated

The Hemophilia Inhibitor Eradication Trial

Hemophilia A With Inhibitor

United States
Swedish Orphan Biovitrum

Active, not recruiting

A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health (A-MORE)

Hemophilia A

Spain, Germany, Czechia, Italy, Estonia, Finland, Greece, Netherlands, Saudi Arabia, Slovenia, Sweden, Switzerland, United Kingdom
Swedish Orphan Biovitrum
Bioverativ Therapeutics Inc.

Completed

Study of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Failed Previous ITI Therapies (ReITIrate)

Hemophilia A

Ireland, United Kingdom, Germany, United States, Canada, Slovenia, Sweden
Swedish Orphan Biovitrum

Completed

A Study to Evaluate the Real-world Usage and Effectiveness of Elocta and Alprolix in Patients With Haemophilia A or B (PREVENT)

Haemophilia A | Haemophilia B

Germany
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

Hemophilia A With Inhibitors

United States, Spain, Canada, Belgium, France, Bulgaria, Italy, United Kingdom, Japan, Germany
Takeda
Intra-Cellular Therapies, Inc.

Terminated

Safety and Tolerability of Multiple Doses of ITI-214 in Healthy Adults and in Adults With Stable Schizophrenia

Schizophrenia

United States
Bioverativ Therapeutics Inc.

Completed

Pharmacokinetics of rFVIIIFc at Two Vial Strengths

Severe Hemophilia A

United States, United Kingdom, Australia
Intra-Cellular Therapies, Inc.

Not yet recruiting

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Healthy Volunteers

United States
Oregon Research Institute

Completed

Transitional Treatment of Adolescents in Family Therapy (Transitions)

Substance Abuse

United States
Intra-Cellular Therapies, Inc.

Completed

Receptor Occupancy of ITI-007 Using Positron Emission Tomography (PET) in Patients With Stable Schizophrenia

Schizophrenia

United States
Intra-Cellular Therapies, Inc.

Terminated

ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease

Agitation in Dementia, Including Alzheimer's Disease

United States
Intra-Cellular Therapies, Inc.

Completed

Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure

Heart Failure, Systolic

United States
Intra-Cellular Therapies, Inc.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ITI-214 in Parkinson's Disease

Parkinson Disease

United States
Intra-Cellular Therapies, Inc.

Completed

Study of ITI-007 in Healthy Geriatric Volunteers and in Geriatric Patients With Dementia

Alzheimer's Disease

United States
Intra-Cellular Therapies, Inc.

Completed

Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted Globally

Bipolar Depression

United States, Russian Federation, Ukraine, Bulgaria, Serbia, Colombia
Intra-Cellular Therapies, Inc.

Completed

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

Bipolar Depression

United States
The Cleveland Clinic

Completed

Comparison of Glenoid Position Using SmartBones

Anatomic Total Shoulder Arthroplasty

United States
Craig Seaman

Terminated

Weight-based Dosing in Hemophilia A

Hemophilia

United States
Henrik Wiggers

Recruiting

Physiological Effects of Lactate in Individuals With Chronic Heart Failure

Heart Failure, Systolic

Denmark
Intra-Cellular Therapies, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

A PET Study Following a Single Oral Dose of ITI-333 in Healthy Subjects

Healthy Volunteers

United States
Immunomic Therapeutics, Inc.

Completed

Study To Evaluate The Safety, Tolerability And Immunogenicity Of 4 mg Of ITI-3000 In Patients With Polyomavirus-Positive Merkel Cell Carcinoma (MCC)

Merkel Cell Carcinoma

United States
University of Aarhus

Completed

The Role of Lactate in Lipolysis and Catabolism in Humans (LILACH)

Healthy | Hyperlactatemia | Lactate

Denmark
Ankara City Hospital Bilkent

Completed

Lactate Clearance in Hospital-acquired Pneumonia

Pneumonia | Mortality | Prognosis | Lactate

Turkey
Centre Hospitalier Universitaire de Nice

Completed

Evaluating Prognostic Contribution of Lactate on Recovery of Spontaneous Cardiac Activity After Cardiac Arrest (PROLAC)

Cardio-respiratory Arrest, Prolactin

France
Universidad del Rosario

Completed

Serum Lactate in Acute Mesenteric Ischemia

Mesenteric Ischemia

Colombia
Institut d'Anesthesiologie des Alpes Maritimes

Withdrawn

Lactate to Treat Hypoglycemia

Hypoglycemia

France
Hualien Tzu Chi General Hospital

Completed

Prognostic Value of Peak Lactate During Cardiopulmonary Bypass in Adult Cardiac Surgeries

Cardiopulmonary Bypass | Lactate
Innogene Kalbiotech Pte. Ltd

Completed

Efficacy, Safety of Hypertonic Lactate Soln. as Fluid Resuscitation Compared With Ringer's Lactate in Post-CABG Pats

Low Cardiac Output

Indonesia
Assiut University

Completed

Lactate Levels During Cardiopulmonary Bypass in Pediatric Patients

Heart Defects, Congenital

Egypt
University Hospital, Lille

Recruiting

Utility of Sodium Lactate Infusion During Septic Shock (ULIS1)

Septic Shock

France
Rigshospitalet, Denmark

Completed

Hyperlactatemia During and After Tumorcraniotomy

Brain Tumor | Surgery | Anesthesia | Hyperlactatemia

Denmark
HaEmek Medical Center, Israel

Completed

Intrapartum Hydration

Labor Stage, First | Labor Stage, Second

Israel
Cairo University

Not yet recruiting

a Novel Index for Tissue Perfusion in Predicting Outcome in Patients With Septic Shock

Septic Shock

Egypt
Khoo Teck Puat Hospital

Unknown

Study of Synovial Lactate Level as Marker of Septic Arthritis

Septic Arthritis

Singapore
Radboud University Medical Center
European Foundation for the Study of Diabetes; Dutch Diabetes Research Foundation

Completed

The Effect of Intravenous Lactate on Brain Lactate Concentrations During Hypoglycemia

Type 1 Diabetes Mellitus With Hypoglycemia

Netherlands
George Washington University
Dasman Diabetes Institute; Nadia Zghoul, PhD, Dept of Clinical Research

Completed

Magnesium Treatment of Inflammation in Disorders of Glucose Homeostasis (MagInGlu)

Non-Insulin Dependent Diabetes Mellitus

Kuwait
Hartford Hospital

Unknown

Magnesium to Reduce Implantable Cardioverter Defibrillator (ICD) Shocks and Improve Patient's Quality of Life.

Quality of Life | Arrhythmia | Hypomagnesemia

United States
University of Aarhus

Not yet recruiting

Does Co-administration of Lactate to an Oral Glucose Tolerance Test Lower the Glucose Response?

Metabolic Syndrome | Insulin Resistance | PreDiabetes
Assiut University

Recruiting

Serum Lactate and Ulcerative Colitis

Ulcerative Colitis

Egypt
The Second Hospital of Hebei Medical University

Unknown

Early Lactate Clearance Rate in Sepsis

Early Lactate Clearance

China
Institut d'Anesthesiologie des Alpes Maritimes
Université de Nice Sophia Antipolis; Medical University of Grenoble

Completed

Preventive Sodium Lactate and Traumatic Brain Injury

Head Trauma

France
National Cancer Institute (NCI)

Active, not recruiting

Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Recurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States
University of Texas Southwestern Medical Center

Recruiting

POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies

Hemophilia A | Factor VIII

United States
Erasme University Hospital

Not yet recruiting

Hypertonic Lactate After Cardiac Arrest (LATTE)

Cardiac Arrest | Ischemia Reperfusion Injury | Anoxic Brain Injury
Innogene Kalbiotech Pte. Ltd

Completed

The Efficacy of Hypertonic Lactate Solution in CABG(Coronary Artery Bypass Grafting) Patients

Low Cardiac Output

Indonesia
Proteostasis Therapeutics, Inc.

Completed

Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis

Healthy Volunteer - Complete | Cystic Fibrosis - Complete

United States, Belgium, United Kingdom, France, Germany, Canada, Denmark, New Zealand, Australia
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospital Patients (FLUID)

Fluid Therapy

Canada
Erasmus Medical Center
Albert Schweitzer Hospital; Sint Franciscus Gasthuis; Medical Center Rijnmond... and other collaborators

Completed

Early Lactate-Directed Therapy in the Intensive Care Unit (ICU)

Hyperlactatemia | Tissue Hypoxia

Netherlands
University of Calgary

Not yet recruiting

Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis (STRIPE)

Post-ERCP Acute Pancreatitis

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