Search clinical trials for: empagliflozin/metformin

Total 2970 results

Ain Shams University
Future University in Egypt

Unknown

Metformin Use in Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
Azienda Ospedaliero-Universitaria di Parma

Completed

Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes

Type 2 Diabetes

Italy
Instituto Nacional de Cancerologia de Mexico

Unknown

Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma

EGFR Gene Mutation | Tyrosine Kinase Mutation | Non-Small Cell Adenocarcinoma

Mexico
Nicholas Mitsiades

Withdrawn

Study of Metformin With Simvastatin for Men With Prostate Carcinoma

Prostate Carcinoma

United States
Ain Shams University

Completed

Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy

Diabetes Mellitus

Egypt
Sanofi

Completed

Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficiently Controlled on Basal Insulin (Lixilan-L-CN)

Type 2 Diabetes Mellitus

China
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Juvenile Myelomonocytic Leukemia | Recurrent Disease | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Childhood Solid Neoplasm | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia... and other conditions

United States, Canada
Takeda

Completed

Efficacy and Safety of Voglibose Compared With Acarbose in Participants With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Completed

Antidiabetic Effects on Intrahepatic Fat

Type2 Diabetes | Non-Alcoholic Fatty Liver Disease

China
London Health Sciences Centre

Unknown

Metformin and Simvastatin Use in Bladder Cancer

Bladder Cancer

Canada
Chipscreen Biosciences, Ltd.

Completed

Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.

T2DM

China
Novo Nordisk A/S

Completed

Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin (SIT2MIX)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of, India, Malaysia, Turkey, Argentina, Greece, Australia, Portugal, Thailand, Brazil
The University of Texas Health Science Center at...
AstraZeneca

Completed

Effect of Chronic Exenatide Therapy on Beta Cell Function and Insulin Sensitivity in T2DM

Diabetes Mellitus, Type 2

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Study of the Effect of Dapagliflozin on the Pharmacokinetics of Warfarin or Digoxin in Healthy Subjects

Type 2 Diabetes Mellitus

United States
Eli Lilly and Company

Withdrawn

A Study of LY3526318 in Healthy Male Japanese Participants

Healthy

Japan
Novartis Pharmaceuticals

Completed

VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Spain, Poland, South Africa, Taiwan, Hong Kong, Norway, Italy, Bulgaria, Latvia, Lithuania, Germany, Turkey, Argentina, Israel, Korea, Republic of, Dominican Republic, Guatemala, Brazil, Colombia, Peru, Philippines, Russian Federation and more
Bial - Portela C S.A.

Completed

Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers

Neuropathic Pain

Portugal
National Taiwan University Hospital
Merck Sharp & Dohme LLC; Schering-Plough

Unknown

The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin

Chronic Hepatitis C

Taiwan
Alkeus Pharmaceuticals, Inc.

Enrolling by invitation

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Stargardt Disease | Stargardt Macular Degeneration | Stargardt Macular Dystrophy | Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

United States
Medical University of Vienna
AstraZeneca

Completed

Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus. (EXENDA)

Type2 Diabetes | Steatosis, Liver

Austria
Laboratorios Manuell SA
Universidad Nacional Autonoma de Mexico

Unknown

Co-administration of Thiamine Pyrophosphate and Metformin in Type 2 Diabetes

Diabetes Mellitus, Type 2

Mexico
Yonsei University

Unknown

Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes

Type 2 Diabetes Mellitus | Dyslipidemias

Korea, Republic of
Sanofi

Completed

Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Germany
Ohio University
Western University of Health Sciences

Completed

INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes (INSPIRE)

Type 2 Diabetes

United States
Uppsala University
AstraZeneca; Uppsala University Hospital

Completed

Exploratory Study to Investigate the Effect of Dapagliflozin and Exenatide Combined on Body Weight (Dapalost)

Obesity

Sweden
Massimo Falconi

Active, not recruiting

Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study (CAOS)

Pancreatic Cancer | Overall Survival | Disease Free Survival

Italy
University of Maryland, Baltimore

Completed

Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition

Bile Salt Export Pump (BSEP) Transporter | Polysorbate 80

United States
Merck Sharp & Dohme LLC

Completed

Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)

Diabetes Mellitus, Type 2
Damanhour University
Alexandria University

Completed

Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO) (METNEO)

Breast Cancer Female

Egypt
Case Comprehensive Cancer Center

Completed

Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
Sanofi

Completed

Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients (GetGoal-Duo-2)

Type 2 Diabetes

United States, Canada, Chile, Czech Republic, Estonia, France, Germany, Hungary, Italy, Latvia, Lithuania, Mexico, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
AstraZeneca
Bristol-Myers Squibb

Completed

Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects

Type 2 Diabetes Mellitus

United States
University of Leipzig

Completed

Exercise Versus Niacin in Patients With Coronary Artery Disease (CAD) and Low High-Density Lipoproteins (HDL)

Coronary Disease | Hypolipoproteinemia

Germany
Fundació Sant Joan de Déu

Recruiting

A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS) (SPIOMET4HEALTH)

Polycystic Ovary Syndrome (PCOS)

Norway, Italy, Denmark, Spain, Austria, Turkey
Sanofi

Completed

Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Drugs (LIXILAN JP-L)

Type 2 Diabetes Mellitus

Japan
Peking Union Medical College Hospital

Unknown

Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

Polycystic Ovary Syndrome

China
Washington University School of Medicine
National Institute of Mental Health (NIMH)

Completed

Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight

Depression

United States
Janssen Research & Development, LLC

Completed

An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy

Diabetes Mellitus, Type 2

United States, Romania, Canada, Russian Federation, Czech Republic, Slovakia, Mexico
Sponsor GmbH
iOMEDICO AG

Completed

Sequential Study to Treat Renal Cell Carcinoma

Renal Cell Carcinoma

Germany
Sanofi

Completed

Insulin Glulisine in Type 2 Diabetic Patients (Basal Plus)

Diabetes Mellitus, Type 2

Russian Federation, United States, United Kingdom
Kaiser Permanente
Patient-Centered Outcomes Research Institute; Henry Ford Health System; HealthPartners... and other collaborators

Recruiting

Comparison of Type 2 Diabetes Pharmacotherapy Regimens (ON TARGET DM)

Cardiovascular Diseases | Type 2 Diabetes Mellitus

United States
Ain Shams University

Not yet recruiting

Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome

Poly Cystic Ovary Syndrome
Sanofi

Completed

iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)

Type 2 Diabetes Mellitus

China
Amgen

Completed

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Advanced Hepatocellular Carcinoma | Inoperable Hepatocellular Carcinoma
Chinese Anti-Cancer Association

Completed

Urea Cream Treatment Sorafenib-Associated HSFR in HCC

Hepatocellular Carcinoma

China
Emory University
Bristol-Myers Squibb; National Cancer Institute (NCI); National Institutes of...

Active, not recruiting

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Refractory Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma | Stage IVC Colorectal Cancer

United States
Xian-Jun Yu

Completed

Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection

Stage IA Pancreatic Adenocarcinoma | Stage IB Pancreatic Adenocarcinoma | Stage IIA Pancreatic Adenocarcinoma | Stage IIB Pancreatic Adenocarcinoma

China
Boehringer Ingelheim

Completed

Two-way Crossover Study in Healthy Male and Female Subjects to Evaluate the Bioequivalence of Jentadueto®.

Healthy

Russian Federation
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Daiichi... and other collaborators

Completed

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Type 2 Diabetes

United States

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