Search clinical trials for: Empagliflozin/Metformin FDC

Total 5923 results

Janssen Research & Development, LLC

Completed

Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food

Healthy Volunteers

United States
AstraZeneca

Completed

A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin

Type 2 Diabetes Mellitus

United States, Poland, Mexico, Hungary, Spain, Romania, South Africa, Denmark, Czechia, Sweden
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Bristol-Myers Squibb

Completed

A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
Rehab Werida
University of Alexandria

Recruiting

Dapagliflozin in Type 2 Diabetes Mellitus Patients (T2DM) With Nonalcoholic Fatty Liver Disease (NAFLD)

Type 2 Diabetes | Nonalcoholic Fatty Liver Disease

Egypt
Organon and Co

Completed

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)

Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia
University of Utah

Active, not recruiting

Role of Metformin on Muscle Health of Older Adults

Insulin Resistance | Muscle Atrophy

United States
Butler Hospital
National Institute of Mental Health (NIMH)

Completed

Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

Substance-Related Disorders | Depression | HIV Infections

United States
Assiut University

Recruiting

USE THE SYSTEMIC METFORMIN IN MELASMA

Melasma

Egypt
Hernando Gomez
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Enrolling by invitation

Safety and Feasibility of Metformin for Sepsis Induced AKI

Sepsis | Septic Shock | Acute Kidney Injury | Metformin

United States
Seoul National University Bundang Hospital

Completed

Initial Combination of Gemigliptin and Metformin on Microbiota Change (INTESTINE)

Diabetes

Korea, Republic of
Mannkind Corporation

Completed

Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Brazil, Spain, Argentina, Canada, Chile, Mexico, Poland, Russian Federation, Ukraine, Czech Republic
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
Maastricht University Medical Center

Recruiting

Empagliflozin for Peripheral Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction | Microvascular Dysfunction

Netherlands
Tanta University

Not yet recruiting

Comparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcoholic Steatohepatitis

Non Alcoholic Steatohepatitis

Egypt
Ann & Robert H Lurie Children's Hospital of Chicago

Not yet recruiting

SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease (SLIDE)

NAFLD | Non-Alcoholic Fatty Liver Disease | Pediatric NAFLD

United States
Matthieu Pelletier-Galarneau, MD MSc

Not yet recruiting

Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging (SWEET-HEART)

Myocardial Suppression
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease

Kidney Disease, Chronic

United States, Spain, Korea, Republic of, Belgium, Australia, Hong Kong, India, Canada, China, Germany, Italy, Japan, Malaysia, Finland, Switzerland, Turkey, Hungary, Poland, Portugal, Philippines, Czechia, Greece, Bulgaria, Brazil, Arg... and more
Medical University of Graz
Medical University of Vienna; Johannes Kepler University of Linz; Paracelsus... and other collaborators

Completed

Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction (EMMY)

Acute Myocardial Infarction

Austria
National University of Malaysia

Unknown

Effect of SGLT2 Inhibition on OCT-A Parameters in Diabetic CKD

Diabetes Mellitus | Chronic Kidney Diseases | Diabetic Retinopathy

Malaysia
Merck Sharp & Dohme LLC

Completed

A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)

Type 2 Diabetes Mellitus
University of Minnesota

Not yet recruiting

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

Oral Leukoplakia

United States
Fudan University

Recruiting

Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)

Diabete Mellitus | Pancretic Cancer

China
Lille Catholic University
Centre Hospitalier Arras

Recruiting

Impact of Metformin on Leptin Transport in Cerebrospinal Fluid of Obese Patients (LEPTOB)

Obesity Without Type 2 Diabetes, With BMI>30

France
Bethesda Diabetes Research Center
University Medical Center Groningen; Maastricht University Medical Center; Medical... and other collaborators

Recruiting

Pregnancy Outcomes: Effects of Metformin Study (POEM Study) (POEM)

Insulin Resistance | Gestational Diabetes

Netherlands
Chang Gung Memorial Hospital

Unknown

Gut Microbiota and Bile Acids in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Metformin | YH1

Taiwan
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin For Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Canada
Hospices Civils de Lyon

Unknown

Metformin Use in Chronic Kidney Disease: The CKD-Met Study (CKD-Met)

Type 2 Diabetes | Chronic Kidney Disease

France
Woman's
AstraZeneca

Completed

Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women (DAPA-GDM)

Diabetes Prevention in Women After GDM Who Are at High-risk

United States
Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Shenzhen People's Hospital

Unknown

Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

Type 1 Diabetes Mellitus | Metformin

China
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Boehringer Ingelheim

Completed

Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects

Healthy

Germany
Children's Hospital Los Angeles

Terminated

Metformin and Transient Hyperglycemia

Hyperglycemia | Diabetes Mellitus | Insulin Resistance | Acute Lymphoblastic Leukemia

United States
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

Non-Insulin-Dependent Diabetes Mellitus

Spain, Germany, Belgium, United Kingdom, Ireland, Netherlands, Italy, France, Mexico, Switzerland, Lithuania
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
Maria Sandberg Westerstahl

Terminated

Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents

Cardiovascular Diseases

Sweden
National Cancer Institute (NCI)

Completed

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

Obesity | Colorectal Cancer | Adenomatous Polyp

Canada, United States
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome
University of Hawaii
National Institute of General Medical Sciences (NIGMS)

Unknown

Metformin for HIV Inflammation

Coronary Artery Disease | HIV

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fasted, Healthy, Adult Subjects

Healthy

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects

Healthy

United States
AstraZeneca

Completed

A Study to Evaluate the Effect of Dapagliflozin on Blood Glucose Level and Renal Safety in Patients With Type 2 Diabetes (DERIVE)

Type 2 Diabetes Mellitus

United States, Italy, Spain, Sweden, Canada, Bulgaria, Poland, Czechia
Novo Nordisk A/S

Completed

Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States, Puerto Rico
Huazhong University of Science and Technology
Hubei Xinhua Hospital; Wuhan Iron and Steel Workers' Hospital; Wuhan Pu-Ai Hospital

Completed

Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

China
Laboratorios Silanes S.A. de C.V.

Completed

Effect of Oral Combination Therapy in a Single Dosage Form in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Mexico
Woman's
Novo Nordisk A/S

Completed

Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)

Type 2 Diabetes Mellitus | Metabolic Syndrome | Impaired Glucose Tolerance | Gestational Diabetes Mellitus | Disorder of Glucose Regulation

United States

Search clinical trials for: Empagliflozin/Metformin FDC

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