Search clinical trials for: Escherichia Coli Endotoxin

Total 1243 results

Rigshospitalet, Denmark

Unknown

Study of Renal Blood Flow During Human Endotoxemia

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
University of Alabama at Birmingham
American Fibromyalgia Syndrome Association

Completed

The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia

Fibromyalgia

United States
University of California, Los Angeles

Completed

An Inflammatory Challenge Using Endotoxin

Inflammatory Response | Alcohol Use Disorder | Craving | Depressed Mood

United States
Rigshospitalet, Denmark

Completed

Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Medical University of Vienna

Completed

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Healthy Subjects | Imparied Retinal Vascular Reactivity

Austria
Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
Medical University of Vienna

Completed

Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.

Retina | Regional Blood Flow | Endotoxin, Escherichia Coli

Austria
University of Aarhus

Completed

The Effects of Amino Acid Supplement During Acute Inflammation.

Metabolic Diseases | Inflammation | Febrile Illness Acute

Denmark
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Terminated

Effects of GSK2798745 on Alveolar Barrier Disruption in a Segmental Lipopolysaccharide (LPS) Challenge Model

Healthy Volunteers

Germany
John Sundy

Completed

Role of TLR4 in Environmental Asthma

Asthma

United States
Jiangsu Province Centers for Disease Control and...
Chengdu Olymvax Biopharmaceuticals Inc.; PLA Army Medical University

Completed

A Clinical Trial to Evaluate a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults

Staphylococcus Aureus Infection

China
José Raimundo Araujo de Azevedo

Not yet recruiting

Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship

Antimicrobial Resistance
Medical University of Vienna

Completed

Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans

Healthy

Austria
Aarhus University Hospital
University of Aarhus; Lundbeck Foundation

Completed

Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?

Glucose Metabolism Disorders | Inflammation

Denmark
NIZO Food Research

Completed

Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli (CORAL)

Gastroenteritis | Diarrhea | Bacterial Infections | Escherichia Coli Infections

Netherlands
Xiamen Innovax Biotech Co., Ltd
Xiamen University; Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Completed

A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)

Hepatitis E

China
Intercell USA, Inc.

Completed

ETEC Logistics Trial (TREK) (Trek)

Diarrhea

United States, Guatemala, Mexico
Washington University School of Medicine
Doris Duke Charitable Foundation

Completed

Assessing NOS Uptake With PET Imaging in Lung Inflammation

Lung Inflammation

United States
Xiamen Innovax Biotech Co., Ltd

Completed

A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )

Hepatitis E

China
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

PET Imaging of Endotoxin-induced iNOS Activation

Pneumonia

United States
National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
Erasmo Spaziani

Recruiting

Probiotic After Acute Colonic Diverticulitis

Therapy | Diverticulitis, Colonic

Italy
Advagene Biopharma Co. Ltd.

Completed

A Phase 2, Double-blind Study to Evaluate Intranasal Trivalent Influenza Virus Vaccine in Healthy Adult

Influenza Infection

Taiwan
International Vaccine Institute
Indian Council of Medical Research; Institute of Child Health; National Institute... and other collaborators

Unknown

Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants

Diarrhea | Cholera | Vibrio Infections

India
Penn State University
United States Department of Agriculture (USDA)

Completed

Safety and Feasibility of an Endotoxemia Model

Inflammation | Cardiovascular Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase 1 Study of dmLT ID Vaccination in Healthy Adults

Gastroenteritis Escherichia Coli

United States
Xiamen Innovax Biotech Co., Ltd

Completed

A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule)

Hepatitis E

China
International Vaccine Institute
Bill and Melinda Gates Foundation; Thrasher Research Fund; Open Philanthropy

Not yet recruiting

Safety and Immunogenicity of Hecolin® in Healthy Pregnant Women

Hepatitis E Infection

Pakistan
Xiamen Innovax Biotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention

Completed

A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial)

Hepatitis E

China
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

Asthma | Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal

United States
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BI 653048 BS H3PO4 Capsule Assessing Endotoxin-induced Inflammatory Response in Healthy Male Subjects

Healthy
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Recruiting

The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Active, not recruiting

Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Jun Zhang
Xiamen Innovax Biotech Co., Ltd; Beijing Wantai Biological Pharmacy Enterprise...

Recruiting

The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
University of California, Los Angeles
National Institute of Mental Health (NIMH)

Completed

Inflammation-Induced Depressed Mood: The Role of Social Neurocognitive Mechanisms

Depression

United States
Xiamen University
Xiamen Innovax Biotech Co., Ltd; Center for Disease Control and Prevention,...

Not yet recruiting

Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls

Cervical Cancer | Cervical Intraepithelial Neoplasia | Persistent Infection

China
Xiamen Innovax Biotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention; Dongtai City Centers...

Completed

Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female

Cervical Cancer | Cervical Intraepithelial Neoplasia | Vaginal Intraepithelial Neoplasia | Vulvar Intraepithelial Neoplasia | Persistent Infection

China
Beijing Health Guard Biotechnology, Inc
National Institutes for Food and Drug Control, China; Yunnan Center for Disease... and other collaborators

Active, not recruiting

A Study to Evaluate the Immunogenicity and Safety of HPV Vaccine in Healthy Female Participants Aged 9-26 Years in China

Human Papillomavirus Infection

China
University of California, Los Angeles

Completed

Cytokine-Associated Depression and Social Pain

Depression

United States
University of California, Los Angeles
National Institute on Aging (NIA)

Recruiting

Aging and Reward System Response to Inflammation and Anxiety Study (ARIA)

Depression | Inflammation | Anhedonia | Anxiety | Aging

United States
University of California, Los Angeles

Active, not recruiting

Sleep and Healthy Aging Research on Depression for Younger Women

Depression | Anhedonia

United States
Michael Irwin, MD

Completed

Sleep and Healthy Aging Research for Depression (SHARE-D) Study (SHARE-D)

Depression in Old Age

United States
Radboud University Medical Center
UMC Utrecht; Prothya Biosolutions

Completed

In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II (VECTORII)

Sepsis | Inflammation | Endotoxemia | Innate Immune Response

Netherlands
National Institute of Allergy and Infectious Diseases...

Terminated

UMD rPA Regimen Trial in Adults

Bacillus Anthracis (Anthrax)

United States
M.D. Anderson Cancer Center

Recruiting

Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)

Prostate Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of Sublingual dmLT for ETEC

Gastroenteritis Escherichia Coli

United States
Aarhus University Hospital

Completed

Peripheral Effects of Endotoxin on Insulin Resistance

Healthy

Denmark
Robert J Noveck, M.D.
Foundation for the National Institutes of Health

Completed

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans

Healthy

United States

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