Search clinical trials for: Febuxostat IR

Total 407 results

Medical University of Lodz

Completed

Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis

Allergic Rhinitis

Poland
Astellas Pharma Taiwan, Inc.

Completed

A Study to Evaluate Safety and Efficacy of Oral Febuxostat in Patients With Gout

Gout

Taiwan
Gui Xiaoting

Recruiting

Changes in Serum, Follicular Fluid SREBP1c and LRG1 Levels in PCOS Patients and Correlation With Insulin Resistance

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

China
Geestelijke Gezondheidszorg Eindhoven (GGzE)
Maastricht University

Not yet recruiting

EMDR Versus Imagery Rescripting for Trauma-Related Intrusions

Depression | Stress Disorders, Post-Traumatic
Bayer

Completed

A Study to Learn How the Study Treatment BAY3283142 Taken as Single Dose by Mouth Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function of Similar Age, Gender, and Weight

Renal Impairment | Chronic Kidney Disease | Healthy Volunteers

Germany
Pharmtechnology LLC
Altasciences Company, Inc.

Completed

Bioequivalence Study of Two Formulations of Febuxostat 120 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions

Bioequivalence

Canada
Takeda

Completed

Effect of Febuxostat on Blood Pressure

Hypertension

United States
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Febuxostat-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia With or Without Gout

Japan
TWi Biotechnology, Inc.

Completed

A Proof-of-Concept Study of AC-201 to Prevent Gout Flares

Gout Flares

Taiwan
NeuroDerm Ltd.

Active, not recruiting

Efficacy, Safety and Tolerability Study of ND0612 vs. Oral Immediate Release Levodopa/Carbidopa (IR-LD/CD) in Subjects With Parkinson's Disease Experiencing Motor Fluctuations (BouNDless)

Parkinson's Disease

United States, Israel, Spain, France, Russian Federation, Austria, Italy, Belgium, Czechia, Hungary, Netherlands, Poland, Portugal, Slovakia, Ukraine, United Kingdom
Pfizer
Medivation, Inc.

Completed

A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin

Alzheimer's Disease | Huntington's Disease

United States
Stallergenes Greer

Active, not recruiting

Safety and Efficacy of STALORAL® Birch 300 IR in a Paediatric Population With Birch Pollen-induced ARC w/o Asthma (YOBI)

Allergic Rhinoconjunctivitis | Birch Pollen Allergy

Germany
Daewon Pharmaceutical Co., Ltd.

Completed

Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR and Pelubiprofen SR (as a Pelubiprofen 45 mg) Tablet in Healthy Subjects

Healthy Males
Grünenthal GmbH

Completed

A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it

Pain | Chronic Pain | Neuropathic Pain | Visceral Pain

Germany
Arthrosi Therapeutics

Completed

Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients

Gout Patients

New Zealand
Tanta University

Recruiting

Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia

Hyperuricemia | Non Alcoholic Steatohepatitis

Egypt
Takeda

Completed

Dose-Response, Safety and Efficacy of Febuxostat in Subjects With Gout

Gout
TWi Biotechnology, Inc.

Completed

A Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Gout

Gout

Taiwan
Erasme University Hospital
Fonds National de la Recherche Scientifique; Fonds Erasme

Completed

Uric Acid Effects on Endothelium and Oxydative Stress

Hypertension | Oxidative Stress | Cardiovascular System | Endothelial Function

Belgium
GlaxoSmithKline

Completed

Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)

Restless Legs Syndrome | Restless Legs Syndrome (RLS)

United States
AMO Development, LLC

Recruiting

Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia

Refractive Error

United States
Elcelyx Therapeutics, Inc.

Completed

Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States, Puerto Rico
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)

Healthy

Finland
Assiut University

Not yet recruiting

Association of Triglyceride Glucose Index and HOMA IR as Predictors of Vascular Complications of DM Type 2

Type 2 Diabetes Mellitus
Bayer
Merck Sharp & Dohme LLC; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF (VITALITY-HFpEF)

Chronic Heart Failure With Preserved Ejection Fraction

Spain, United States, Belgium, Singapore, Taiwan, Canada, Japan, Italy, Austria, Bulgaria, Germany, Greece, Israel, Poland, Portugal, Hungary, Russian Federation, Argentina, Colombia, Malaysia, South Africa
Daewon Pharmaceutical Co., Ltd.

Completed

Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR TID and Pelubiprofen SR (as a Pelubiprofen 90 mg) Tablet QD in Healthy Subjects

Healthy
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Single Doses of ORM-12741 (Nebula PK 1)

Healthy

Finland
Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
AstraZeneca
Ardea Biosciences, Inc.

Completed

A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia Patients

Gout and Asymptomatic Hyperuricemia

Japan
Ardea Biosciences, Inc.

Completed

Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat (CRYSTAL)

Tophaceous Gout

Poland, United States, Canada, Australia, New Zealand, Switzerland
Infrared Cameras Incorporate

Completed

A Study to Validate Comparability of an Infrared Thermographic Camera Versus Oral, Forehead, and Ear Thermometers When Determining Body Temperature in Adult Participants

Temperature Change, Body

United States
University of Bern
Bundesamt für Gesundheit; Sentinella Netzwerk; Schweizerische Gesellschaft für... and other collaborators

Completed

Intervention Study to Improve Antibiotic Prescription in Outpatient Care (SAPI)

Respiratory Tract Infections | Urinary Tract Infections

Switzerland
Elcelyx Therapeutics, Inc.

Completed

Assessing the PK of Met DR, Met IR, and Met XR in Healthy Subjects

Healthy Subjects
Endo Pharmaceuticals

Completed

Open-Label Safety and Tolerability Study of Oxymorphone for Acute Postoperative Pain in Pediatric Subjects.

Postoperative Pain

United States
Alexion

Recruiting

A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants

Healthy Participants

United Kingdom
Kowa Research Institute, Inc.

Completed

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

Dyslipidemia

United States
Yonsei University

Recruiting

Respiratory Measurement Using Infrared Camera and Electrical Impedance Tomography for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia

Patients Undergoing Transurethral Prostate or Cystectomy Under Spinal Anesthesia

Korea, Republic of
Ottawa Hospital Research Institute
Carleton University

Completed

NEC Thermography Infrared Imaging Study

Necrotizing Enterocolitis

Canada
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Ironwood Pharmaceuticals, Inc.
Medpace, Inc.

Terminated

A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment

Gout | Chronic Kidney Disease (CKD)

United States, Hungary, Poland, Czechia
Bayer

Completed

Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects

Pharmacokinetics

Germany
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids

Diarrhea Predominant Irritable Bowel Syndrome

United States
Stallergenes Greer

Completed

Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis

Allergy

Germany
GlaxoSmithKline

Completed

Clinical Evaluation of Ropinirole Prolonged Release/Extended Release (PR/XR) Tablet for Adjunctive Therapy to L-dopa in Subjects With Advanced Parkinson's Disease

Parkinson Disease

Japan
Stallergenes Greer

Completed

Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis

Allergic Rhinitis
AstraZeneca

Terminated

Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
Merck KGaA, Darmstadt, Germany

Completed

Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, Germany
Ferrer Internacional S.A.

Terminated

Single Dose Study to Compare the Pharmacodynamics of Torasemide-PR 10 mg,Torasemide-IR 10 mg and Furosemide-IR 40 mg in Patients With Compensated Heart Failure

Compensated Heart Failure

Spain

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