Search clinical trials for: Folic Acid Antagonists

Total 50565 results

H. Lee Moffitt Cancer Center and Research Institute
Sanofi

Terminated

Pemetrexed &Oxaliplatin in Patients w Recurrent NSCLCa After Failure to Platinum Based Adjuvant Chem

Lung Cancer

United States
SCRI Development Innovations, LLC
Eli Lilly and Company

Completed

Preoperative Pemetrexed and Carboplatin for Select Stage IB, II, and III Non-Squamous Non-Small-Cell Lung Cancer

Non Small Cell Lung Cancer

United States
Ain Shams University

Unknown

Four Versus Six Cycles of Pemetrexed/Platinum for MPM

Malignant Pleural Mesothelioma

Egypt
Eli Lilly and Company

Completed

Pemetrexed and Best Supportive Care Versus Placebo and Best Supportive Care in Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer

China, Italy, Australia, Poland, Netherlands, India, Austria, Spain, Bulgaria, United States, Greece, Turkey, Brazil, Croatia, Czech Republic, Germany, Hungary, Korea, Republic of, Romania, Taiwan
GlaxoSmithKline

Completed

Study of Pazopanib and Pemetrexed in Advanced Non-small Cell Lung Cancer

Lung Cancer, Non-Small Cell

Denmark, United Kingdom
Cancer Institute and Hospital, Chinese Academy...

Completed

Trial of Pemetrexed in Combined With Cisplatin for the Treatment of Advanced Breast Cancer

Locally Advanced Malignant Neoplasm

China
Medical University of South Carolina

Terminated

Cisplatin and Pemetrexed With Radiation Followed by Lobectomy (CisPemXetSrg)

Nonsquamous Nonsmall Cell Neoplasm of Lung | Nonsmall Cell Lung Cancer Stage III

United States
Eli Lilly and Company

Completed

A Study Comparing of Two Different Chemotherapy Regimens, in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

Lebanon, Egypt, Saudi Arabia
NovoCure Ltd.

Completed

NovoTTF-100L in Combination With Pemetrexed (Alimta®) for Advanced Non-small Cell Lung Cancer

NSCLC | Non-small Cell Lung Cancer

Switzerland
Zhejiang Cancer Hospital

Unknown

A Study of Pemetrexed Plus Carboplatin Combined With Radiation in Patients With Inoperable Locally Advanced Non-small Cell Lung Cancer (LA-NSCLC) (RT0801) (NSCLC)

Non-Small Cell Lung Cancer

China
Eli Lilly and Company

Completed

Pemetrexed/Carboplatin Non-Small Cell Lung Cancer (NSCLC) Elderly Patients

Non Small Cell Lung Cancer

France
Eli Lilly and Company

Completed

Study of Pemetrexed Plus Cisplatin in Advanced Gastric Cancer

Neoplasm, Gastric

Taiwan, Argentina, Mexico, Korea, Republic of
Henan Cancer Hospital

Recruiting

Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma

Central Nervous System Lymphoma

China
Eli Lilly and Company

Completed

Study of Enzastaurin Versus Placebo With Pemetrexed for Participants With Advanced or Metastatic Lung Cancer

Non-small Cell Lung Cancer

United States, France, Italy, Korea, Republic of, Germany, Portugal
Norwegian University of Science and Technology
St. Olavs Hospital

Terminated

Pemetrexed in Advanced Non-Small-Cell Lung Cancer: at Progression vs Maintenance Therapy After Induction Chemotherapy (IDA)

Carcinoma, Non-small-cell Lung

Norway
Swiss Group for Clinical Cancer Research

Completed

Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

Switzerland, Germany
Aydin Adnan Menderes University

Completed

Pulpotomy With Various MTA Materials and Ferric Sulphate

Pulpotomy

Turkey
Sun Yat-sen University

Unknown

Intermittent and Maintenance of Icotinib in Combination With Pemetrexed/Carboplatin Compared With Icotinib Single Drug in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation

Lung, Carcinoma

China
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer (NRR)

Lung Cancer | Metastatic Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium and Carboplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Lung Cancer

United States
Eli Lilly and Company

Completed

Pemetrexed Plus Cisplatin Bi-Weekly, in Patients With Urothelial Cancer (Metastatic, Locally Advanced or Non-Resectable)

Urologic Neoplasms

Spain
Eli Lilly and Company

Completed

Pemetrexed Plus Cisplatin as First-Line Treatment in Stage IV or Recurrence of Gastric Cancer

Gastric Cancer

Russian Federation
AGUNCO Obstetrics and Gynecology Centre

Completed

Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome

Polycystic Ovary Syndrome

Italy
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Effect of Folic Acid in Levodopa Treated Parkinson's Disease Patients

Parkinson Disease

Bangladesh
Eunice Kennedy Shriver National Institute of Child...

Completed

Folic Acid and Zinc Supplementation Trial (FAZST) (FAZST)

Pregnancy | Spontaneous Abortion | Live Birth

United States
Sanofi

Completed

Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis (SARILNIUSATURN)

Uveitis

Italy, Turkey, Spain, United States, Czechia, France
Endocyte

Completed

Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors

Solid Tumors | Non Small Cell Lung Carcinoma

United States
Omar Mamdouh Shaaban

Completed

Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies (LMWH-APAN)

Recurrent Miscarriage
Georgetown University

Completed

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

End Stage Renal Disease | Hyperhomocysteinemia

United States
Medical University of Lublin

Completed

Myo-inositol Therapy on the Dynamics of Embryo Development in Patients Suffering From PCOS Undergoing ICSI Treatment

Polycystic Ovary Syndrome | Infertility

Poland
University of Messina

Completed

Myo-inositol in Obese Pregnant Women

Gestational Diabetes

Italy
Guangzhou Medical University

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Leptomeningeal Metastasis
Seoul National University Hospital
Gyeongsang National University Hospital; Chungnam National University Hospital and other collaborators

Recruiting

Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS) (SPECTRUM)

DLBCL

Korea, Republic of
Shanghai Zhongshan Hospital

Not yet recruiting

Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma

Sensitivity
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy

Malignant Mesothelioma

United States
Guangzhou Institute of Respiratory Disease
Shanghai Junshi Bioscience Co., Ltd.

Unknown

Efficacy and Safety of Toripalimab (JS001) Combined With Pemetrexed and Anlotinib for Patients With T790M Positive Non-Small Cell Lung Cancer After Osimertinib Resistance

IIIb/IV NSCLC With T790M Positive Mutations Failed to Osimertinib Therapy

China
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Haploidentical NK Cells After Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC) (Medi-NK)

Non-small Cell Lung Cancer

Korea, Republic of
Universität Duisburg-Essen

Terminated

Biomarker Study Accompanying the AIO-TRK-0114 Study (MARBLE) (Trans-MARBLE)

Non-small-cell Lung Cancer With Somatic EGFR Mutations
Sun Yat-sen University

Unknown

APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLC (APPEAL)

Lung Cancer

China
Tang-Du Hospital

Unknown

Pemetrexed Combined With Synchronous Gefitinib as Adjuvent Therapy in Patient With EGFR Mutant Lung Adenocarcinoma

Lung Neoplasms

China
Eli Lilly and Company

Completed

A Study of Home Administration of Pemetrexed as Maintenance Treatment for Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer Metastatic | Nonsquamous Non-Small Cell Neoplasm of Lung | Non-Small Cell Lung Cancer Stage IIIB

United Kingdom, Sweden
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Pemetrexed and Oxaliplatin in Treating Patients With Locally Advanced Head and Neck Cancer

Head and Neck Cancer

United States
Eli Lilly and Company

Terminated

A Study to Treat Small Cell Lung Cancer With a Combination of Cisplatin, Pemetrexed, and Radiotherapy

Small Cell Lung Cancer | SCLC | Carcinoma, Small Cell

Netherlands, Belgium
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
Syntrix Biosystems, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Once-Weekly Oral Aminopterin for the Treatment of Subjects With Moderate-To-Severe Psoriasis

Psoriasis

United States
Quadram Institute Bioscience
University of Sheffield; Food Standards Agency, United Kingdom

Completed

Increasing Folate Status of a General Population(FOLSUPP STUDY)

Healthy

United Kingdom
British University In Egypt
Ain Shams University

Unknown

A Pilot Study to Assess the Efficacy and Safety of Folic Acid and/or Vitamin B Complex on Hepatitis C Infected Patients Treated With Pegylated Interferon and Ribavirin.

Hepatitis C

Egypt
AstraZeneca

Recruiting

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment (SAFFRON)

Carcinoma | Non-Small-Cell Lung

China, Israel, Spain, United States, Canada, Italy, Korea, Republic of, Belgium, Bulgaria, Vietnam, Japan, United Kingdom, Brazil, France, Philippines, Taiwan, Thailand, Germany, Poland, Austria, Greece, Turkey, Argentina, Hong Kong, Chile and more
Takeda

Active, not recruiting

TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

United States, Spain, France, Korea, Republic of, Hong Kong, Australia, Taiwan, United Kingdom, Canada, Turkey, Italy, China, Germany, Japan, Austria, Belgium, Greece, Israel, Netherlands, Portugal, Russian Federation, Singapore, Sw... and more
The First Hospital of Jilin University
The Second Hospital of Hebei Medical University; Second Affiliated Hospital... and other collaborators

Recruiting

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Leptomeningeal Metastasis

China

Search clinical trials for: Folic Acid Antagonists

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