Search clinical trials for: GABA

Total 2389 results

King Abdul Aziz Specialist Hospital

Completed

Non Invasive and Invasive Ventilation Post Extubation

Respiratory Failure With Hypoxia

Saudi Arabia
Minia University

Unknown

Impact of Adding Midzolam to Bupavicaine 0.5% in Regional Spinal Anaesthesia on Maternal Middle Cerebral Artery Velocimetry in Parturients With Severer Preeclampsia

Midazolam in Preeclamptic Patients

Egypt
University Hospital "Sestre Milosrdnice"

Unknown

What Amount of Stress is Enough for a Successful Conception?

Stress | Stress, Emotional | In Vitro Fertilization | Midazolam Adverse Reaction

Croatia
UCB Biopharma S.P.R.L.

Terminated

A Long-term Safety and Tolerability Study of USL261 in Patients With Seizure Clusters

Epilepsy

United States
Paion UK Ltd.
PRA Health Sciences

Completed

Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users

Abuse, Drug

United States
Pfizer

Completed

THE EFFECT OF MULTIPLE DOSES OF PF-06835919 ON THE PHARMACOKINETICS OF A SINGLE ORAL MIDAZOLAM DOSE IN HEALTHY PARTICIPANTS

Healthy Volunteer

Belgium
Eli Lilly and Company

Terminated

A Tasisulam and Midazolam Drug Interaction Study in Cancer Patients

Advanced Cancer

France
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Midazolam

Healthy

United Kingdom
Charles University, Czech Republic

Completed

Changes of Skin Resistance After Midazolam and After the End of Anaesthesia

Anesthesia

Czechia
Universidad de Valparaiso
Hospital Carlos Van Buren

Unknown

Tablet-based Interactive Distraction Preoperative Anxiety in Children: A Randomized Controlled Trial (TABLET)

Children Under General Anaesthesia

Chile
Indonesia University

Completed

Comparison Between Efficacy of Music Therapy and Intravenous Midazolam 0.02 mg/kgBW in Reducing Preoperative Anxiety

Cancer

Indonesia
LEO Pharma

Terminated

A Phase I Study With LEO 32731 and Midazolam in Healthy Male Subjects

Psoriasis Vulgaris

United Kingdom
McGill University Health Centre/Research Institute...

Completed

Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department

Lacerations | Anxiety
H. Lundbeck A/S

Completed

MK0928 Study in Adult Patients With Primary Insomnia (0928-040)(COMPLETED)

Primary Insomnia
H. Lundbeck A/S

Terminated

Elderly Primary Insomnia Polysomnographic Study (0928-002)(TERMINATED)

Primary Insomnia
University of California, San Diego
National Institute of Mental Health (NIMH)

Completed

PharmacofMRI (Functional Magnetic Resonance Imaging) of Anxiolytic Medications (Alprazolam)

Anxiety Disorders

United States
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Midazolam in Healthy Male Volunteers

Healthy
Bristol-Myers Squibb

Completed

Study to Assess the Effect of BMS-791325 on the Pharmacokinetics of Midazolam in Healthy Subjects

Hepatitis C

United States
Nathan Kline Institute for Psychiatric Research
National Institute of Mental Health (NIMH)

Completed

Lorazepam-Induced Toxicity in the Aged

Anxiety Disorders | Generalized Anxiety Disorder

United States
Isfahan University of Medical Sciences

Completed

Alprazolam as Conscious Sedation for Upper Gastrointestinal Endoscopy

Diagnostic Esophagogastroduodenoscopy

Iran, Islamic Republic of
Kamuzu University of Health Sciences

Terminated

Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children.

Status Epilepticus | Convulsions

Malawi
Advocate Hospital System

Withdrawn

The Effect of Etomidate on Outcomes of Trauma Patients

Trauma
Seoul National University Hospital

Completed

Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)

Intubation

Korea, Republic of
Ziv Hospital

Completed

Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients

Cirrhosis

Israel
Teva Pharmaceuticals USA

Completed

Alprazolam Extended-Release 3mg Tablets Bioequivalence Study Under Non-fasting Conditions

Healthy

United States
Teva Pharmaceuticals USA

Completed

Alprazolam Extended-Release 3mg Tablets Bioequivalence Study Under Fasting Conditions

Healthy

United States
AstraZeneca

Completed

AZD1981 Midazolam CYP4503A Induction Study

Healthy Male Volunteer

Sweden
Hospital Universitari Son Dureta
Fondo de Investigacion Sanitaria

Terminated

Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension

Traumatic Brain Injury

Spain
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

HCV-796 and Midazolam Drug Interaction Study in Healthy Subjects

Healthy

United States
Yale University
National Center for Research Resources (NCRR)

Completed

Family-Centered Behavioral Preparation for Surgery

Anxiety

United States
Stanford University

Completed

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.

Sleep Initiation and Maintenance Disorders

United States
The University of Hong Kong

Recruiting

Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia

Insomnia

China
Eisai Inc.
Purdue Pharma LP

Completed

A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users

Insomnia Disorders

Canada
Assistance Publique - Hôpitaux de Paris

Recruiting

Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies (EGELY)

Dementia With Lewy Bodies

France
Yeungnam University Hospital

Not yet recruiting

Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (REST)

Remimazolam | Midazolam

Korea, Republic of
Yangzhou University

Recruiting

Remimazolam for Postoperative Atrial Fibrillation (RePAF)

Coronary Artery Bypass Grafting | Remimazolam

China
ViiV Healthcare

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

HIV Infections

United States
Zhujiang Hospital
The Third Affiliated Hospital of Guangzhou Medical University; First Affiliated... and other collaborators

Recruiting

Effect of Remimazolam With Protocolized Sedation on Critical Ill, Mechanical Ventilated Patients Compared With Midazolam

Sedation and Analgesia

China
Indivior Inc.

Completed

Study of Potential CYP3A4 Induction by INDV-2000 in Healthy Adults

Healthy

United States
University of Liege

Completed

Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia

Knee Osteoarthritis | Arthroplasty Complications | Sedation Complication | Anesthesia Complication | Hypnotic; Anxiety Disorder

Belgium
Shionogi

Completed

A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants

Healthy Volunteers

United States
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics, and Food Effect Study of RV299 in Healthy Adults

Respiratory Syncytial Virus Infections

United Kingdom
ViiV Healthcare

Completed

First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4004280 in Healthy Participants

HIV Infections

United States
ViiV Healthcare

Completed

First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants

HIV Infections

United States
Phathom Pharmaceuticals, Inc.

Completed

Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants

Healthy Volunteers

United States
Concert Pharmaceuticals

Completed

Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects

Health Volunteers

United States
Shire

Completed

Pharmacokinetic Interaction Between SSP-004184 (SPD602) and Midazolam in Healthy Adult Subjects

Healthy

United States
The First Affiliated Hospital, Guangzhou University...

Unknown

Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD

Sleep Initiation and Maintenance Disorders | Renal Dialysis

China
Novartis Pharmaceuticals

Completed

Investigate Effect of Secukinumab on the PK of Midazolam in Patients With Mod to Sev Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

United States
Eli Lilly and Company
Algorithme Pharma Inc; CoLucid Pharmaceuticals; Cognitive Research Corporation

Completed

The Effects of Lasmiditan on Simulated Driving Performance - Healthy Participants

Migraine

Canada

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