Search clinical trials for: GABA-A Receptor Antagonists

Total 10797 results

University of Kansas Medical Center
National Cancer Institute (NCI)

Recruiting

Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens

Breast Cancer | Risk Reduction

United States
University of Louisville

Recruiting

Vaginal Baclofen Suppositories in Chronic Pelvic Pain

Chronic Pelvic Pain Syndrome

United States
Medical University of Gdansk

Enrolling by invitation

Observation of Clozapine Treatment Safety in Bipolar Disorder. (CloGD)

Bipolar Disorder

Poland
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Response to Clozapine in Treatment Resistant Schizophrenia: A Longitudinal Magnetic Resonance Spectroscopy Study

Schizophrenia

Canada
Tirat Carmel Mental Health Center
Technion, Israel Institute of Technology; HaEmek Medical Center, Israel; Beersheva... and other collaborators

Completed

Clozapine Plasma Levels and the Relationship to the Genetic Polymorphism in Shizophrenic Patients

Schizophrenia

Israel
Novartis

Completed

A Study to Evaluate the Safety and Efficacy of Clozapine in Patients With Treatment-resistant Schizophrenia

Schizophrenia

Japan
Memorial Hospital of Rhode Island

Completed

Study of Clozapine for the Treatment of Psychosis in Patients With Idiopathic Parkinson's Disease

Parkinson Disease
Tanta University

Recruiting

Baclofen Versus Gabapentin in Preventing Postoperative Pain After Laparoscopic Sleeve Gastrectomy

Post Operative Pain

Egypt
University of Pennsylvania

Completed

Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in Women

Healthy

United States
Jack Edinger, PhD
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Completed

Sequenced Therapies for Comorbid and Primary Insomnias

Primary Insomnia | Insomnia Comorbid to Psychiatric Disorder

United States, Canada
Transcept Pharmaceuticals

Completed

Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet

Insomnia

Netherlands
Massachusetts General Hospital

Completed

Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer

Breast Cancer | Hot Flashes | Sleep Disorders

United States
University of North Carolina, Chapel Hill
Medical University of South Carolina; Otsuka America Pharmaceutical; Barnes-Jewish...

Terminated

Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients

Brain Injury | Hyponatremia

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia

Schizophrenia

Poland, United States, Belgium, Taiwan, Spain, Malaysia, Korea, Republic of, Thailand, Slovakia, Croatia
Essentia Health

Terminated

Preventing Alcohol Withdrawal With Oral Baclofen (BACLOFEN III)

Alcoholism | Alcohol Withdrawal

United States
Sha'ar Menashe Mental Health Center
Ministry of Health, Israel

Completed

Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients

Alcohol Dependence

Israel
Maastricht University
Medtronic

Completed

Dutch National ITB Study in Children With Cerebral Palsy

Cerebral Palsy | Spasticity

Netherlands
Novartis

Completed

A Long Term Study of Clozapine in Patients With Treatment-resistant Schizophrenia

Schizophrenia
KBP Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Chronic Kidney Disease

United States
Pharnext S.C.A.
Worldwide Clinical Trials

Active, not recruiting

Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PREMIER)

Charcot-Marie-Tooth Disease

United States, Spain, Belgium, Italy, Israel, Canada, Denmark, France, Germany
University of California, San Francisco
National Cancer Institute (NCI)

Withdrawn

Developing Individualized Strategies to Prevent Nausea and Vomiting (PDNVF)

Postoperative Nausea and Vomiting | Genetic Polymorphisms

United States
Seoul National University Hospital

Unknown

Therapeutic Drug Monitoring for Individualized Clozapine Therapy

Schizophrenia

Korea, Republic of
Actelion

Completed

Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female Subjects

Healthy

Germany
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Efficacy and Safety of High Dose Baclofen for Alcohol Dependence

Alcoholism

United States
Centre for Addiction and Mental Health
Canadian Tobacco Control Research Initiative

Terminated

Baclofen for Smoking Cessation in a Non-Psychiatric Population (Baclofen)

Nicotine Dependence

Canada
University of North Carolina, Chapel Hill

Completed

Efficacy and Tolerability of Baclofen for Alcohol Dependence

Alcohol Dependence

United States
University Ghent
Research Foundation Flanders

Completed

Influence of Endurance Exercise and Histamine Receptors on the Gene Expression in Skeletal Muscle

Exercise | Histamine

Belgium
Yazd Medical University
Yazd Research & Clinical Center for Infertility

Completed

Mild Stimulation Protocol Versus Microdose Gonadotropin-releasing Hormone Agonist Flare up Protocol in Poor Responders

Pregnancy

Iran, Islamic Republic of
Xuanwu Hospital, Beijing

Not yet recruiting

Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery

Overactive Bladder | Spinal Vascular Disorder Nos
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

Sleep Disorders

United States
University Hospital, Caen

Recruiting

Clozapine and Haematologic Malignancies: Observational and Retrospective Study Using the WHO Pharmacovigilance Database (CLOZARIX)

Lymphoma | Leukemia

France
Seoul National University Bundang Hospital

Unknown

F-18 Altanserin PET Study of Patients Receiving Clozapine (APC)

Schizophrenia | Schizoaffective Disorder

Korea, Republic of
Brigham and Women's Hospital

Recruiting

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Hypertension | Primary Aldosteronism

United States
Hospices Civils de Lyon

Terminated

Role of FXR in Hepatitis C Virus Replication (GGST)

Chronic Hepatitis C

France
Hackensack Meridian Health

Recruiting

Post-operative Urinary Retention (POUR) Following Thoracic Surgery (POUR)

Urinary Retention

United States
Astellas Pharma China, Inc.

Completed

A Study to Compare How Tamsulosin is Absorbed to the Body After Administration of Two Types of Tamsulosin Formulation Under Fed and Fasted Conditions in Chinese Healthy Subjects

Healthy | Pharmacokinetics of Tamsulosin Hydrochloride

China
All India Institute of Medical Sciences, Bhubaneswar

Completed

Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia

Treatment Resistant Schizophrenia

India
Impulse Dynamics

Terminated

Cardiac Contractility Modulation (CCM) Therapy in Subjects With Medically Refractory Heart Failure (IMPULSE-HF)

Heart Failure

Sweden, Austria, Germany, Poland
Centre for Addiction and Mental Health

Recruiting

Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

Schizophrenia | Schizoaffective Disorder

Canada
King Abdullah International Medical Research Center

Recruiting

The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19) (PROMISE)

Moderate Covid19

Saudi Arabia
University of Pennsylvania

Withdrawn

A Study of Baclofen ER (CURE)

Cocaine Dependence

United States
VA Office of Research and Development

Completed

Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS

Benign Prostatic Hyperplasia | Lower Urinary Track Symptoms

United States
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Unknown

Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients (DPABIAP)

Coronary Artery Disease

China
Pfizer

Recruiting

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors (CDK4i)

Breast Neoplasms | Prostate Cancer | Adenocarcinoma of Lung | Solid Tumors | Liposarcoma | CRC

China, United States, United Kingdom, Mexico, Czechia, Japan, Slovakia, Argentina
Anders Fink-Jensen, MD, DMSci
Rigshospitalet, Denmark; University of Copenhagen

Completed

The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring.

Schizophrenia

Denmark
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing the Efficacy and Tolerability of Ziprasidone vs. Clozapine for the Treatment of Schizophrenia in Patients Who Continue to Have Symptoms on or Cannot Tolerate Other Antipsychotic Drugs (MOZART)

Schizophrenia

Italy
Indivior Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Controlled Release Arbaclofen Placarbil (XP19986) in Patients With Gastroesophageal Reflux Disease

GERD

United States
Kaohsiung Veterans General Hospital.

Completed

Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer

Peptic Ulcer

Taiwan
University College, London
British Heart Foundation

Completed

Early Mineralocorticoid Receptor Antagonist Treatment to Reduce Myocardial Infarct Size (MINIMISE-STEMI)

ST-elevation Myocardial Infarction

United Kingdom
Northwell Health
National Institute of Mental Health (NIMH)

Completed

Electroconvulsive Therapy in Clozapine Refractory Schizophrenia

Schizophrenia

United States

Search clinical trials for: GABA-A Receptor Antagonists

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