Search clinical trials for: GDC-0449
Total 1873 results
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Genentech, Inc.Completed
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Stanford UniversityNational Cancer Institute (NCI); University Hospitals Cleveland Medical CenterCompletedRecurrent Skin Cancer | Basal Cell Carcinoma of the SkinUnited States
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National Cancer Institute (NCI)Completed
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National Cancer Institute (NCI)CompletedAdult MedulloblastomaUnited States
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National Cancer Institute (NCI)Genentech, Inc.TerminatedChronic Graft Versus Host DiseaseUnited States
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Lisa BaxRoche Pharma AG; Genentech, Inc.TerminatedPancreatic Ductal AdenocarcinomaUnited Kingdom
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Genentech, Inc.CompletedA Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449) in Operable Basal Cell CarcinomaBasal Cell CarcinomaUnited States
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Genentech, Inc.Approved for marketingBasal Cell CarcinomaUnited States
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National Cancer Institute (NCI)CompletedRecurrent Childhood MedulloblastomaUnited States
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National Cancer Institute (NCI)Active, not recruitingMesenchymal Chondrosarcoma | Dedifferentiated Chondrosarcoma | Unresectable Primary Central Chondrosarcoma | Clear Cell Chondrosarcoma | Locally Advanced Chondrosarcoma | Metastatic Chondrosarcoma | Primary Central ChondrosarcomaFrance
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National Cancer Institute (NCI)CompletedRefractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell MyelomaUnited States
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National Cancer Institute (NCI)CompletedRecurrent Childhood MedulloblastomaUnited States
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National Cancer Institute (NCI)CompletedAdult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain TumorUnited States
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Genentech, Inc.CompletedBasal Cell CarcinomaAustralia, France, United States, Germany, Belgium, United Kingdom
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NYU College of DentistryGenentech, Inc.CompletedKeratocystic Odontogenic TumorUnited States
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The Lymphoma Academic Research OrganisationRoche Pharma AGTerminatedChronic Lymphocytic Leukemia | Primary Central Nervous System Lymphoma | Diffuse Large B-cell Lymphoma | Indolent Non-hodgkin LymphomaFrance
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Genentech, Inc.National Cancer Institute (NCI); Sidney Kimmel Comprehensive Cancer Center...CompletedUnspecified Adult Solid Tumor, Protocol Specific
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UCSF Benioff Children's Hospital OaklandGenentech, Inc.CompletedBasal Cell Nevus Syndrome | Gorlin SyndromeUnited States
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Genentech, Inc.CompletedNon-Hodgkin's Lymphoma, Solid TumorCanada, United States
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Genentech, Inc.Completed
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); GlaxoSmithKline; Genentech, Inc.; Brain Science...RecruitingIntracranial Meningioma | Recurrent Meningioma | NF2 Gene MutationUnited States
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Anne ChangNational Cancer Institute (NCI); Merck Sharp & Dohme LLCCompletedSkin Basal Cell CarcinomaUnited States
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National Cancer Institute (NCI)CompletedRecurrent Uterine Corpus Sarcoma | Chondrosarcoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult... and other conditionsUnited States
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National Cancer Institute (NCI)TerminatedStage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast CarcinomaUnited States
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National Cancer Institute (NCI)Active, not recruitingAdvanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma | Hematopoietic and Lymphatic System NeoplasmUnited States
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National Cancer Institute (NCI)CompletedRecurrent Pancreatic Carcinoma | Stage IV Pancreatic CancerUnited States
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National Cancer Institute (NCI)CompletedAdenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic CancerUnited States
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UCSF Benioff Children's Hospital OaklandGenentech, Inc.CompletedBasal Cell Nevus Syndrome | Gorlin's SyndromeUnited States
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National Cancer Institute (NCI)Active, not recruitingPancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Pancreatic Acinar Cell Carcinoma | Adult Solid NeoplasmUnited States
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Radboud University Medical CenterCompletedProstatic Neoplasms | Immunotherapy | Vaccines | Dendritic CellsNetherlands
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Memorial Sloan Kettering Cancer CenterPfizerCompleted
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Carol BernierVirginia Polytechnic Institute and State UniversityRecruitingCardiac Arrest | Pulseless Electrical ActivityUnited States
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Genentech, Inc.Completed
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Novo Nordisk A/SCompletedNon-alcoholic Fatty Liver DiseaseChina
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Ascentage Pharma Group Inc.Suzhou Yasheng Pharmaceutical Co., Ltd.RecruitingEsophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Malignant Pleural Mesothelioma | Advanced Solid CancerChina
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Novo Nordisk A/SCompletedNon-alcoholic SteatohepatitisJapan
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Genentech, Inc.CompletedMetastatic Colorectal Cancer | Ovarian Cancer | Basal Cell CarcinomaUnited States
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Genentech, Inc.Completed
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Genentech, Inc.Completed
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National Cancer Institute (NCI)TerminatedProstate Adenocarcinoma | Stage IIA Prostate Cancer AJCC v7 | Stage IIB Prostate Cancer AJCC v7United States
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National Cancer Institute (NCI)CompletedAdenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric CancerUnited States
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Genentech, Inc.CompletedHealthy VolunteerUnited States
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Jonsson Comprehensive Cancer CenterActive, not recruiting
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Jean-Luc Van LaethemRoche Pharma AGUnknownPancreatic Adenocarcinoma ResectableBelgium
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Fougera Pharmaceuticals Inc.CompletedInflammatory Rosacea
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Novo Nordisk A/SCompleted
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Genentech, Inc.CompletedHealthy VolunteersUnited Kingdom
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Genentech, Inc.Completed