Search clinical trials for: GDC-0917

Total 1913 results

Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological Malignancies

Non-hodgkin's Lymphoma

China
UNC Lineberger Comprehensive Cancer Center
United States Department of Defense; Bellicum Pharmaceuticals

Recruiting

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

Small Cell Lung Carcinoma | Lung Cancer | Non Small Cell Lung Cancer

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.

Recruiting

A Study of GNC-038, a Tetra-specific Antibody, in Participants With R/R Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.

Recruiting

A Study of GNC-035, a Tetra-specific Antibody, in Participants With Relapsed/Refractory Hematologic Malignancy

Hematologic Malignancies

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.

Recruiting

A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors

Solid Tumor | Recurrent Glioma

China
Johns Hopkins University

Active, not recruiting

Implementation of the Live Donor Champion Program (LDC)

End-stage Renal Disease

United States
Open Innovation Partners, Inc.
Open Innovation Partners

Suspended

TR1801-ADC in Patients With Tumors That Express c-Met

Unspecified Adult Solid Tumor, Protocol Specific

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.

Withdrawn

A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Solid Tumors

Breast Cancer | Solid Tumor

China
West China Hospital
RemeGen Co., Ltd.

Not yet recruiting

RC48-ADC in Adjuvant/Salvage Treatment of HER2 Positive Non-muscle-invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

Phase Ib/II Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Non-hodgkin's Lymphoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-038, a Tetra-specific Antibody, in Patients With Central Nervous System Lymphoma (PCNSL) and Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Primary Central Nervous System Lymphoma | Secondary Central Nervous System Lymphoma

China
Shenzhen Geno-Immune Medical Institute

Recruiting

GD2/CD56 Bi-specific CAR-T Cell Therapy

Malignant Disease

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Breast Cancer

Breast Cancer

China
Institute of Tropical Medicine, Belgium
Ecole Nationale de Santé Publique, Rabat, Morocco

Completed

Improve Detection and Management of Gestational Diabetes Through the Primary Health Care Level in Morocco

Gestational Diabetes Mellitus in Pregnancy

Morocco
Progenics Pharmaceuticals, Inc.

Completed

A Study of PSMA ADC in Subjects With Metastatic Castration-resistant Prostate Cancer (mCRPC)

Prostate Cancer

United States
Centre Hospitalier Universitaire de Nīmes

Terminated

The Global Shoulder Concept (GSC) Method Versus Classic Physical Therapy for Shoulder Tendinitis

Tendinopathy | Shoulder

France
Progenics Pharmaceuticals, Inc.

Completed

Extended Study of Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer

Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

Study to Assess the Acceptability/Swallowability of DRV-Containing FDC Tablets in HIV-1 Infected Adolescents, Using Matching Placebo Tablets

HIV-1

United States
Yung Shin Pharm. Ind. Co., Ltd.
Changhua Christian Hospital

Completed

A Study to Evaluate the Effects of RCN3028 on Moderate to Severe Vasomotor Symptoms in Women (RDC)

Hot Flashes | PMS

Taiwan
Soroka University Medical Center

Completed

Prevention of Diabetes Mellitus Type 2 in Women Post Gestational Diabetes Mellitus Diagnosis (GDM)

Gestational Diabetes Mellitus
Genentech, Inc.

Completed

A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants

Healthy Volunteers

United Kingdom
Centre Leon Berard

Recruiting

MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma (COTESARC)

Sarcoma,Soft Tissue

France
M.D. Anderson Cancer Center

Withdrawn

Venetoclax and Eprenetapopt for the Treatment of Relapsed of Refractory Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma | Refractory Mantle Cell Lymphoma

United States
Genentech, Inc.

Completed

A Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and the Effect of Food and Proton Pump Inhibition on GDC-0941 Tablet Pharmacokinetics in Healthy Volunteers

Healthy Volunteers

United States
AbbVie
Genentech, Inc.

Active, not recruiting

Study to Assess Adverse Events and Change in Disease State of Oral Venetoclax in Combination With Subcutaneous (SC) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy in China

Acute Myeloid Leukemia (AML)

China
Beijing Tsinghua Chang Gung Hospital

Completed

Thrombolysis Endovascular Treatment of Pulmonary Embolism (STEP)

Pulmonary Embolism | Acute Pulmonary Embolism

China
Genentech, Inc.

Completed

A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy Participants

Healthy Volunteer
The University of Texas Health Science Center,...

Completed

Guidance of Ultrasound in Intensive Care to Direct Euvolemia (GUIDE)

Acute Kidney Injury

United States
Afyon Kocatepe University Hospital

Completed

The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes

Retinal Degeneration | Diabetic Retinopathy | Macula Abnormality | Laser Burn of Retina
University of Connecticut
United States Department of Defense; AMP Human; Park City, UT

Completed

The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress (AMP2)

Electrolyte and Fluid Balance Conditions | Fluid Retention | Dehydration (Physiology) | Heat Stress | Renal Injury | Sodium Retention

United States
National Cancer Institute (NCI)

Active, not recruiting

GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by Surgery

Pancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Pancreatic Acinar Cell Carcinoma | Adult Solid Neoplasm

United States
Memorial Sloan Kettering Cancer Center

Completed

Person-Centered Oncology Care and Choices (P-COCC): Piloting and Initial Randomized Testing of a Combined Values Narrative Interview and Video Education Advance Care Planning Program in Gastrointestinal Oncology Patients

Advanced Gastrointestinal Cancer

United States
Gangnam Severance Hospital

Completed

Remimazolam Bolus for General Anesthesia

Loss of Consciousness

Korea, Republic of
AbbVie

Completed

A Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed/Refractory Acute Lymphoblastic Leukemia or Relapsed/Refractory Lymphoblastic Lymphoma

Lymphoblastic Lymphoma | Acute Lymphoblastic Leukemia (ALL)

United States, Australia
Icahn School of Medicine at Mount Sinai

Withdrawn

To Evaluate the Safety and Efficacy of Ipatasertib (GDC-0068) in Combination With Paclitaxel in Platinum-resistant Recurrent Epithelial Ovarian Cancer

Ovarian Neoplasms

United States
AbbVie
Genentech, Inc.

Active, not recruiting

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Canada, France, Germany, Italy, United Kingdom
Hoffmann-La Roche

Completed

A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma (coBRIM)

Malignant Melanoma

United States, Spain, Hungary, Israel, United Kingdom, Australia, Austria, Belgium, Czechia, France, Germany, Italy, Netherlands, Russian Federation, Sweden, Switzerland, Canada, New Zealand, Norway
Dorothy Bautista, MD
Canadian Blood Services

Enrolling by invitation

Allogenic Plasma Aliquots in the Treatment of Ligneous Conjunctivitis

Ligneous Conjunctivitis, Left Eye

Canada
Genentech, Inc.

Completed

A Study of Paclitaxel With GDC-0941 Versus Paclitaxel With Placebo in Participants With Locally Recurrent or Metastatic Breast Cancer

Breast Cancer

United States, Korea, Republic of, Australia, Austria, Czechia, United Kingdom, Belgium, Spain
Radboud University Medical Center

Completed

Natural Dendritic Cell Vaccines in Metastatic Melanoma Patients

Melanoma

Netherlands
Genentech, Inc.

Completed

A Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With Breast Cancer That Has Spread Beyond the Initial Site, and the Cancer Does Not Have Certain Hormonal Receptors (LOTUS)

Breast Neoplasms

United States, Spain, Korea, Republic of, Taiwan, Italy, Singapore, France, Belgium
Genentech, Inc.
SOLTI Breast Cancer Research Group

Completed

A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer

Breast Cancer

United States, Spain, Portugal
Mathilde Peters, DMD, PhD
Dentsply International; Mott Children's Health Center

Completed

High-strength Glass-ionomer Dental Restorations (ROCK)

Dental Caries

United States
Shanghai Institute Of Biological Products
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.

Advanced Solid Tumor
Shenzhen Geno-Immune Medical Institute
Shenzhen Children's Hospital

Recruiting

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

Neuroblastoma

China
Boehringer Ingelheim

Completed

Bioequivalence Study of Telmisartan Between T80/A5/H12.5 mg FDC Tablet and T80/A5 mg Tab and H12.5 mg Tab Concomitant Use

Healthy

Japan
New York State Psychiatric Institute

Suspended

A Novel Computer-Based Therapy for Social Anxiety

Social Anxiety Disorder

United States
Grifols Therapeutics LLC

Completed

A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary Immunodeficiency

Immunologic Deficiency Syndrome

United States, Canada
TORL Biotherapeutics, LLC
Translational Research in Oncology

Recruiting

First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer

Gastric Cancer | Advanced Solid Tumor | Pancreas Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States

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