Search clinical trials for: GDC-0980

Total 1912 results

Boehringer Ingelheim

Completed

Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers

Healthy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Elotuzumab and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma

Plasma Cell Myeloma | Hematopoietic Cell Transplantation Recipient

United States
Hoffmann-La Roche

Completed

A Study in Healthy Male Subjects to Investigate the Comparability of Pharmacokinetics of the Fixed-Dose Combination of Pertuzumab and Trastuzumab Administered Subcutaneously Using a Handheld Syringe or Using the On-Body Delivery System

Healthy Male Subjects

Australia, New Zealand
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Pharmacokinetics of Rilpivirine/Tenofovir/Emtricitabine After a Single-Oral Administration in Healthy Japanese Adult Male Participants

Healthy

Japan
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in Glioblastoma (Combi G-Vax)

Glioblastoma | Vaccination

Italy
University of Florida
American Society of Nephrology

Withdrawn

Severe Sepsis in Children - IMPRESS-C (IMPRESS-C)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Combining Chemoradiotherapy With Sintilimab in First-Line ICC

ICC

China
Barts & The London NHS Trust

Not yet recruiting

Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF) (ORBICA-AF)

Cardiac Arrhythmia | Persistent Atrial Fibrillation | Catheter Ablation
Beth Israel Deaconess Medical Center
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Recruiting

Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients

Acute Myelogenous Leukemia

United States
Bart Neyns
Vrije Universiteit Brussel

Completed

Autologous TriMix-DC Therapeutic Vaccine in Combination With Ipilimumab in Patients With Previously Treated Unresectable Stage III or IV Melanoma (TriMix-Ipi)

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

Belgium
Beth Israel Deaconess Medical Center

Completed

Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)

Migraine

United States
Oslo University Hospital
Norwegian Cancer Society; Helse Sor-Ost

Completed

Phase II Cancer Vaccine Trial for Patients With Follicular Lymphoma (Lymvac-1)

Follicular Lymphoma

Norway
Janssen Sciences Ireland UC

Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Healthy

Netherlands
University of Florida
National Cancer Institute (NCI)

Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM | Astrocytoma, Grade IV

United States
Bayer

Completed

Bioequivalence Study: 3 mg Estradiol Valerate (EV) With and Without Levomefolate Calcium

Contraception | Ovulation Inhibition

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell Lymphoma

Anaplastic Large Cell Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

Mantle Cell Lymphoma | Blastoid Variant Mantle Cell Lymphoma | Pleomorphic Variant Mantle Cell Lymphoma

United States
Peking Union Medical College Hospital

Recruiting

Toripalimab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

Biliary Tract Neoplasms Immunotherapy

China
Beth Israel Deaconess Medical Center
Bristol-Myers Squibb; Dana-Farber Cancer Institute

Terminated

Dendritic Cell (DC)/Myeloma Fusions in Combination With Nivolumab in Patients With Relapsed Multiple Myeloma

Multiple Myeloma

United States
University Hospital, Ghent
University Ghent; Kom Op Tegen Kanker

Active, not recruiting

MIDRIX4-LUNG Dendritic Cell Vaccine in Patients With Metastatic Non-small Cell Lung Cancer (MIDRIX4-LUNG)

Non-small Cell Lung Cancer Metastatic

Belgium
Shanghai Zhongshan Hospital

Unknown

Cisplatin and Gemcitabine Chemotherapy and Lenvatinib for Patients With Unresectable Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma, Intrahepatic

China
National Cancer Institute (NCI)

Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia

United States
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel and Trastuzumab With or Without Lapatinib in Treating Patients With Stage II or Stage III Breast Cancer That Can Be Removed by Surgery

Male Breast Carcinoma | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7

United States, Puerto Rico
Capital Medical University

Completed

Concurrent Chemoradiation With or Without DC-CIK Immunotherapy in Treating Locally Advanced Esophageal Cancer

Esophageal Carcinoma

China
Capital Medical University

Terminated

Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma

Cancer | Mesothelioma, Malignant

China
Cairo University

Unknown

Remineralization Efficacy of Gum Arabic Varnish.

Remineralization | White Spot Lesion | Caries,Dental

Egypt
Auburn University

Not yet recruiting

Effects of Vitamin D on Skeletal Muscle Strength in Resistance Trained Adult Females

Nutrition Status | Sports Nutritional Sciences | Nutritional Requirements
PDC*line Pharma SAS

Active, not recruiting

Safety, Immunogenicity and Preliminary Clinical Activity Study of PDC*lung01 Cancer Vaccine in NSCLC

Non Small Cell Lung Cancer

Belgium, France, Netherlands, Germany, Poland
Memorial Sloan Kettering Cancer Center

Completed

Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk Neuroblastoma

Neuroblastoma

United States
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Combination Grazoprevir (MK-5172)/Elbasvir (MK-8742) Versus Sofosbuvir + Pegylated Interferon + Ribavirin in Hepatitis C Virus Genotype 1, 4 or 6 Infection (MK-5172-077)

Hepatitis C
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
Grifols Therapeutics LLC

Terminated

Tetanus Immunization in Subjects With No Immunization History or With Tetanus Antibody Levels Below Protective Levels

Tetanus

United States
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

Healthy

United States
GlaxoSmithKline

Completed

Study to Investigate Dose Proportionality of the Fixed Dose Combination of COREG CR and Lisinopril.

Hypertension

United States
Mayo Clinic
National Cancer Institute (NCI); Novartis Pharmaceuticals

Completed

Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
Janssen Research & Development, LLC

Completed

A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants

Healthy

United States
Dartmouth-Hitchcock Medical Center
Harbor Medical Inc.

Completed

Evaluation of Body-worn Multimodal Hand Hygiene System. Impact on Health-Care Associated Infections (Sprixx-ICU)

Nosocomial Infection

United States
GlaxoSmithKline

Completed

Study to Examine the Effect of Food on the Pharmacokinetics of the Fixed Dose Combination of COREG CR and Lisinopril.

Hypertension

United States
RemeGen Co., Ltd.

Recruiting

A Study of RC48-ADC Combination Therapies as First-line Treatment in Advanced Metastatic Gastric Cancer

Gastric Cancer

China
University of Oxford
Biopharma (Orofino Pharmaceuticals Group)

Not yet recruiting

Study to Compare Blood Levels of Ceftriaxone Given by Suppository or Injection. (CefREC)

Healthy

Thailand
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis

Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Monoclonal B-Cell Lymphocytosis | Stage I Small Lymphocytic Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Refractory Melanoma | BRAF V600 Wild Type | Intracranial Melanoma

United States
Medtronic Bakken Research Center

Completed

DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study (DATAS)

Ventricular Fibrillation | Ventricular Tachycardia | Defibrillators, Implantable
Hoffmann-La Roche

Active, not recruiting

A Two-Arm Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Chinese Participants With HER2-Positive Early Breast Cancer

HER2-positive Early Breast Cancer

China
Janssen Sciences Ireland UC

Completed

Relative Bioavailability and Food Effect for Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination

Healthy

Belgium
Mayo Clinic
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma

Melanoma (Skin)

United States
Green Cross Corporation

Completed

A Phase I/IIa Study of GC3110A (Quadrivalent Influenza Vaccine)

Influenza

Korea, Republic of
Centre Jean Perrin
Ministry for Health and Solidarity, France

Recruiting

AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma (NANO-GBM)

Glioblastoma

France
NKMAX Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Anti-tumor Activity of SNK01 (NK Cells) Administered in Combination With Chemotherapy or Chemotherapy / Cetuximab in Local Advanced or Metastatic Non-small Cell Lung Cancer Patients Who Failed Tyrosine Kinase Inhibitor Treatment (SNK_ASTER)

Non-small Cell Lung Cancer

Korea, Republic of
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage IIIA Primary Peritoneal Cancer AJCC v8 | Stage IIIA1 Fallopian Tube Cancer AJCC v8 | Stage... and other conditions

United States

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