Search clinical trials for: GLA-SE adjuvant

Total 9591 results

IDRI
Bill and Melinda Gates Foundation

Completed

Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers

Visceral Leishmaniasis

United States
IDRI
Rockefeller University

Completed

The Effects of GLA (5 mcg) on Human Volunteers

Healthy Volunteers

United States
Oswaldo Cruz Foundation

Recruiting

Anti-Schistosomiasis Sm14-vaccine in Senegal

Vaccination; Infection | Schistosomiasis Mansoni | Schistosomiasis Haematobium

Senegal
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants (HVTN 135)

HIV Infections

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected Cells

HIV Infections

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma That Is Metastatic or Cannot Be Removed by Surgery

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
U.S. Army Medical Research and Development Command
United States Agency for International Development (USAID); IDRI

Completed

Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults

Malaria

United States
National Institute of Allergy and Infectious Diseases...

Completed

LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine

Leishmaniasis

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by Surgery

Stage IV Skin Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Stage IIA Skin Melanoma | Stage IIB Skin Melanoma | Stage IIC Skin Melanoma | Stage IIIA Skin Melanoma

United States
The Immunobiological Technology Institute (Bio-Manguinhos)...
Oswaldo Cruz Institute

Not yet recruiting

Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy Patients

Leprosy

Brazil
Oswaldo Cruz Foundation
IDRI; Biomedical Research Center EPLS; Orygen Biotecnologia SA

Completed

Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children

Schistosomiasis

Senegal
Oswaldo Cruz Foundation
IDRI; Biomedical Research Center EPLS; Orygen Biotecnologia SA

Completed

Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions

Schistosomiasis

Senegal
Access to Advanced Health Institute (AAHI)
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

Phase 1 Clinical Trial of Single-Vial ID93 + GLA-SE in Healthy Adults

Pulmonary TB

United States
Quratis Inc.

Unknown

Phase 1 Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Adolescent

Tuberculosis

Korea, Republic of
Quratis Inc.
IDRI

Unknown

Phase 2a Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Healthcare Workers

Tuberculosis

Korea, Republic of
IDRI
American Leprosy Missions

Completed

Phase 1 LEP-F1 + GLA-SE Vaccine Trial in Healthy Adult Volunteers

Leprosy

United States
Immune Design

Completed

A Proof-of-Concept Trial of GLA-SE in Patients With Merkel Cell Carcinoma

Merkel Cell Carcinoma

United States
IDRI
South African Tuberculosis Vaccine Initiative; Aeras

Completed

Phase 1 ID93 + GLA-SE Vaccine Trial in BCG-Vaccinated Healthy Adult Volunteers

Pulmonary Tuberculosis

South Africa
Rockefeller University
Immune Design; IDRI Corporation

Completed

The Effects of GLA on Human Volunteers

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of EnvSeq-1 and CH505 M5 gp120 Envs Adjuvanted With GLA-SE in Healthy, HIV-Uninfected Adults

HIV Infections

United States
International Vaccine Institute

Recruiting

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Sm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and Madagascar

Schistosomiasis

Burkina Faso, Madagascar
IDRI
Aeras; Paul G. Allen Family Foundation

Completed

Phase 1 ID93 + GLA-SE Vaccine Trial in Healthy Adult Volunteers

Pulmonary Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Immunogenicity of the Vaccine Candidates ID93 + AP10-602 and ID93 + GLA-SE Administered Intramuscularly in Healthy Adult Subjects

Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy Adults

Schistosomiasis

United States
IDRI

Completed

Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteers

Leishmaniasis

United States
University Hospital Tuebingen
University of Copenhagen; Institut de Recherche pour le Developpement; Université... and other collaborators

Completed

Safety and Immunogenicity of the Placental Malaria Vaccine Candidate PAMVAC Variously Adjuvanted (PAMVAC)

Malaria, Antepartum

Benin
Leiden University Medical Center
MRC/UVRI and LSHTM Uganda Research Unit; Texas Tech University Health Sciences...

Not yet recruiting

Sm-p80 Schistosomiasis Challenge Study

Schistosomiasis | Schistosoma Mansoni
IDRI
Wellcome Trust; South African Tuberculosis Vaccine Initiative

Completed

Phase 2a ID93 + GLA-SE Vaccine Trial in TB Patients After Treatment Completion

Pulmonary Tuberculosis

South Africa
Institut National de la Santé Et de la Recherche...
EVI Industries, Inc.; Recherche Clinique Paris Descartes Necker Cochin Sainte... and other collaborators

Completed

Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults (PRIMALVAC)

Malaria

Burkina Faso, France
IDRI
Bill and Melinda Gates Foundation

Completed

Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India

Visceral Leishmaniasis | Post-kala-azar Dermal Leishmaniasis

India
Butantan Institute

Completed

Safety and Immunogencity of H7N9 Influenza Antigen With 2 Adjuvant Formulations in Healthy Adults in Brazil

Influenza | H7N9 Influenza

Brazil
Medicago
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Completed

Immunogenicity, Safety, Tolerability of a Plant-made H5 Virus-like-particle (VLP) Influenza Vaccine.

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases

Canada
Chang Gung Memorial Hospital

Recruiting

Epidemiological Study of Fabry Disease Screening in Chronic Kidney Disease Patients

Fabry Disease

Taiwan
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TB

Tuberculosis, Pulmonary
Oswaldo Cruz Foundation
Financiadora de Estudos e Projetos

Completed

Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis

Schistosomiasis

Brazil
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants (HVTN139)

HIV Infections

South Africa
Fatebenefratelli Hospital
Federico II University; Federal University of Rio Grande do Sul; Royal Brompton... and other collaborators

Recruiting

Stress Echo 2020 - The International Stress Echo Study (SE2020)

Coronary Artery Disease | Heart Failure | Aortic Valve Disease | Pulmonary Arterial Hypertension | Tetralogy of Fallot | Hypertrophic Cardiomyopathy | Athletes Heart

Italy
Boston VA Research Institute, Inc.
Agency for Healthcare Research and Quality (AHRQ)

Completed

Interactive Spaced Education to Optimize Diabetes Care

Diabetes

United States
Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and Chemotherapy (ISILI)

Colorectal Cancer Metastatic

France
University of California, San Francisco

Completed

Cognitive Remediation of Schizophrenia in a Community Mental Health Setting (SECT)

Experimental Condition TCT | Controlled Condition CG

United States
Worcester HIV Vaccine
Brigham and Women's Hospital; Access to Advanced Health Institute (AAHI)

Completed

Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to a New HIV Vaccine: HIV CTL MEP

HIV Infections

United States
Boehringer Ingelheim

Completed

Relative Bioavailability and Tolerability of Two New Different Extended Release Capsules of BIBV 308 SE, Versus a Solution of BIBV 308 SE in Healthy Subjects

Healthy
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults

HIV Infections

United States
MedRelief

Completed

Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study (DPN)

Diabetic Peripheral Neuropathy

United States
Institut National de la Santé Et de la Recherche...
EVI Industries, Inc.; BPRC; Recherche Clinique Paris Descartes Necker Cochin... and other collaborators

Completed

Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults (AMA1-DiCo)

Malaria, Falciparum

Burkina Faso, France
Boehringer Ingelheim

Completed

Relative Bioavailability and Tolerability of Various Experimental Formulations of BIBV 308 SE in Healthy Subjects

Healthy
Protein Sciences Corporation

Completed

Trial to Evaluate the Immunogenicity and Safety of Panblok® (H7 rHA) in Healthy Adults Aged 18 and Older (PSC26)

Influenza

United States
Abbott Medical Devices

Completed

TactiSense IDE Trial of TactiCath SE for Paroxysmal Atrial Fibrillation (TactiSense)

Paroxysmal Atrial Fibrillation

United States, Australia, Italy, Germany
Maastricht Radiation Oncology

Withdrawn

DE-CT in Lung Cancer Proton Therapy (DE-CT)

Non Small Cell Lung Cancer

Netherlands

Search clinical trials for: GLA-SE adjuvant

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