Search clinical trials for: GRT0151Y dose escalation

Total 6383 results

Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects

Healthy Subjects

China
Grünenthal GmbH

Completed

A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure to Investigate the Safety and Tolerability of GRT0151Y and to Find Out Which Single Dose of the Compound is Maximally Tolerated

Pain | Chronic Pain | Acute Pain

Canada
Grünenthal GmbH

Completed

A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body

Acute Pain

France
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study

Rectal Cancer

China
Weill Medical College of Cornell University

Active, not recruiting

PRE-ProstAtectomy MRI-GuidEd Stereotactic Body RadioTherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT) (PREPARE SBRT)

Prostate Cancer

United States
Cliniques universitaires Saint-Luc- Université...

Unknown

Molecular Imaging-based Dose Escalation in HPV Negative Patients With Locally Advanced SCC of the Oropharynx

Head and Neck Cancer

Belgium
National Cancer Institute, Egypt

Recruiting

Multimodality- Adapted Dose Modification in Head and Neck Cancer Radiation Therapy (MART)

Head and Neck Cancer

Egypt
University Hospital Olomouc
University Hospital Ostrava; Masaryk Memorial Cancer Institute

Recruiting

FMISO-based Adaptive Radiotherapy for Head and Neck Cancer (FARHEAD)

Hypoxia | Head and Neck Cancer | Dose Escalation | FMISO

Czechia
Royal North Shore Hospital

Recruiting

Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation (ASPIRE_Multi)

Palliative Radiotherapy

Australia
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Istituto Clinico Humanitas

Recruiting

SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions (STRILL)

Non Small Cell Lung Cancer | Lung Metastases

Italy
Emory University

Completed

Phase I Trial of Stereotactic Radiosurgery Following Surgical Resection of Brain Metastases

Brain Metastasis | Neoplasm

United States
Hinova Pharmaceuticals Aus Pty Ltd

Completed

A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

Australia
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent

Completed

Dose De-escalation to the Elective Nodal Sites in Head and Neck Cancer

Head and Neck Cancer

Belgium
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Stichting tegen Kanker

Recruiting

Dose De-escalation and Sentinel LN Mapping Driven Radiotherapy of Contralateral Neck in Ipsilateral Node Positive HNSCC (SEMIRAHN)

Squamous Cell Carcinoma of Head and Neck

Belgium
Radboud University Medical Center

Terminated

Individualized Dose Prescription in Advanced Stage Lung Cancer Patients Using Modern (Chemo)Radiotherapy (IDEAL-VMAT)

Stage III Non-small Cell Lung Cancer | Individualized Radiation Dose Escalation

Netherlands
University of Pennsylvania

Completed

Ghrelin Dose Finding In Frail Elderly

The Frailty Syndrome

United States
Umeå University

Completed

Dose Escalation With SIB to Intraprostatic/Lymphatic GTV in High Risk Prostate Cancer (PARAPLY-1)

Prostatic Neoplasms | Lymphatic Metastasis

Sweden
Vanderbilt University Medical Center

Withdrawn

Multiple Ascending Dose Putative Cognitive Enhancer VU319

Cognitive Impairment

United States
MacroGenics

Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

Melanoma | Sarcoma | Clear Cell Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Advanced... and other conditions

United States
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
Domain Therapeutics SA

Recruiting

DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours (EPRAD)

Solid Tumor, Adult

France, Belgium
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO) (CARPASCIO)

Non-Hodgkin's Lymphoma | B-Cell ALL | B-Cell CLL

United States
Amgen

Completed

Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia

Leukemia | Myeloid Leukemia | Cancer | Hematologic Malignancies

United States
Qualigen Theraputics, Inc.
Translational Drug Development

Recruiting

Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

Solid Tumor

United States
Maastricht Radiation Oncology

Completed

HI-CHART:Feasibility of High-Dose Accelerated Conformal Radiotherapy

Non-Small-Cell Lung Carcinoma

Netherlands
Oncotartis, Inc.

Unknown

Safety and Efficacy of OT-82 in Participants With Relapsed or Refractory Lymphoma

Lymphoma | Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Lymphoma, T-Cell | Lymphoma, Hodgkin | Lymphoma, Peripheral T-Cell

United States
RasCal Therapeutics, Inc.

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Glioblastoma | Pancreatic Cancer | Lung Cancer | Colon Cancer | Advanced Malignant Solid Neoplasm | RAS Mutation

United States
Royal North Shore Hospital

Completed

Early Investigation of High Precision Radiotherapy Prior to Commencing Standard Radiotherapy for Prostate Cancer (BOOSTER)

Prostate Cancer

Australia
Acea Bio (Hangzhou) Co., Ltd.

Unknown

Safety Study of FLP Injection to Treat Tumor Patients

Advanced Cancer

China
Maastricht Radiation Oncology

Completed

Safety Study of Individualised Radiation Dose Determination for Lung Cancer Patients.

Non-Small-Cell Lung Carcinoma

Netherlands
Vanderbilt University
Vanderbilt University Medical Center

Completed

Putative Cognitive Enhancer VU319

Cognitive Impairment

United States
Medical College of Wisconsin

Recruiting

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

Rectal Adenocarcinoma

United States
Ahon Pharmaceutical Co., Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Unknown

A Phase I Study of FCN-411 in Advanced Non-small Cell Lung Cancer Chinese Patients With EGFR Positive Mutation

Lung Cancer

China
AtlasMedx, Incorporated

Active, not recruiting

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Homologous Recombination Deficiency | Advanced Malignant Neoplasm

United States
University of Kansas Medical Center

Recruiting

Evaluation of Umbilical Cord-Derived Wharton's Jelly Stem Cells for the Treatment of Acute Graft Versus Host Disease

Acute Graft Versus Host Disease

United States
Stanford University
Celgene Corporation

Recruiting

Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation

Leukemia | Leukemia, Myeloid | Monocytic Leukemia

United States
CymaBay Therapeutics, Inc.

Completed

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Homozygous Familial Hypercholesterolemia

Canada, France, Netherlands, Norway
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.

CML, Chronic Phase | CML, Accelerated Phase

China
SenoRx, Inc.
C. R. Bard

Terminated

Safety Study for Short-course Accelerated, Hypofractionated Partial Breast Radiotherapy (APBI) in Women With Early Stage Breast Cancer Using the Contura MLB

Breast Cancer

United States
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore
Abramson Cancer Center of the University of Pennsylvania

Completed

Autophagy Induction After Bortezomib for Myeloma

Multiple Myeloma

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Desensitization With Bortezomib Before a Living Kidney Donation (VELDON)

Patients Awaiting a Living Kidney Donation

France
Janssen Research & Development, LLC

Terminated

A Dose Escalation Study of Duvortuxizumab in Participants With Relapsed or Refractory B-cell Malignancies

Lymphoma, Follicular | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Mantle-Cell | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Leukemia, Lymphocytic, Chronic, B-Cell

United States, France, Spain, Belgium, Israel
University of Liverpool
European and Developing Countries Clinical Trials Partnership (Funder); Joint... and other collaborators

Active, not recruiting

Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load (DERIVE)

HIV/AIDS | Tuberculosis

Uganda
University Hospital, Clermont-Ferrand

Completed

Prevalence, Intensity and Consequences of Bortezomib-induced Neuropathic Disorders. (PREVIB)

Multiple Myeloma | Chemotherapy Induced Peripheral Neuropathy

France
Eli Lilly and Company

Completed

Notch Inhibitor in Advanced Cancer

Advanced Cancer

United States
Kineta Inc.
Merck Sharp & Dohme LLC

Recruiting

A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

Melanoma | Sarcoma | Kidney Cancer | Carcinoma | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Solid Tumor | Prostate Cancer | Colo-rectal Cancer | Thyroid Cancer | Uterine Cancer

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Solid Tumors | Preoperative Aerobic Training

United States
Grupo de Investigación Clínica en Oncología Radioterapia

Unknown

Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Spain

Search clinical trials for: GRT0151Y dose escalation

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