Search clinical trials for: Glucagon receptor antagonist LY2409021

Total 9664 results

University Hospital, Gentofte, Copenhagen
Eli Lilly and Company

Enrolling by invitation

Delineation of the Diabetogenic Role of Extrapancreatic Glucagon in Totally Pancreatectomised Patients Using Glucagon Receptor Antagonism (PX-GRA)

Diabetes After Total Pancreatectomy
Zosano Pharma Corporation

Completed

Safety and Efficacy of ZP-Glucagon to Injectable Glucagon for Hypoglycemia

Hypoglycemia

Australia
Eli Lilly and Company

Completed

Study of LY2409021 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1

Germany
Steno Diabetes Center Copenhagen

Recruiting

Low-Dose Glucagon and Advanced Hybrid Closed-Loop System for Prevention of Exercise-Induced Hypoglycaemia in People With Type 1 Diabetes (The HYPO-AVOID)

Hypoglycemia | Type 1 Diabetes

Denmark
Xeris Pharmaceuticals
Empiristat, Inc.

Completed

G-Pen Compared to Glucagen Hypokit for Severe Hypoglycemia Rescue in Adults With Type 1 Diabetes

Type 1 Diabetes Mellitus | Severe Hypoglycemia | Insulin Hypoglycemia

United States, Canada, Austria
Eli Lilly and Company

Completed

A Study of Nasal Glucagon in Participants With Type 1 Diabetes Mellitus

Hypoglycemia | Diabetes Mellitus, Type 1

Germany
Eli Lilly and Company
Jaeb Center for Health Research; Locemia Solutions ULC

Completed

Assessment of Intranasal Glucagon in Children and Adolescents With Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
Eli Lilly and Company
Locemia Solutions ULC

Completed

Evaluate the Immunogenicity of a Novel Glucagon Formulation

Diabetes Mellitus | Drug-specific Antibodies

Canada
Zealand Pharma

Completed

Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon

Hypoglycemia

Germany
Eli Lilly and Company
Locemia Solutions ULC; T1D Exchange Clinic Network Coordinating Center

Completed

Efficacy and Safety of Nasal Glucagon for Treatment of Hypoglycemia in Adults

Diabetes Mellitus, Type 1

United States
Sanofi

Completed

A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses of SAR438544 in Comparison to Placebo and Glucagon in Healthy Subjects and Type 1 Diabetes Mellitus Patients

Type 1 Diabetes Mellitus

United States
Charite University, Berlin, Germany

Unknown

Glucagon Modulation of Ghrelin Secretion

Obesity | Diabetes Mellitus, Type 1 | Healthy Subjects

Germany
Eli Lilly and Company

Completed

A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus

Diabetes Mellitus

Japan
Adocia

Completed

A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM

Type 1 Diabetes Mellitus

Germany
Zealand Pharma
SynteractHCR

Completed

A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus

Hypoglycemia | Diabetes Mellitus, Type 1

United States, Austria, Canada, Germany
Steno Diabetes Center Copenhagen

Completed

Low-dose Glucagon for Prevention of Exercise-Induced Hypoglycemia in People With Type 1 Diabetes

Hypoglycemia | Type 1 Diabetes

Denmark
University Hospital Bispebjerg and Frederiksberg

Completed

Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition (GLUCAGON)

Drug Overdose | Overdose of Beta-adrenergic Blocking Drug

Denmark
Xeris Pharmaceuticals
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emissary...

Completed

PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients

Hypoglycemia

United States
Zealand Pharma

Completed

A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects

Hypoglycemia | Diabetes Mellitus, Type 1

Canada, United States, Austria, Germany
Université Catholique de Louvain
Fonds National de la Recherche Scientifique; BESPEED

Active, not recruiting

Phenotypic and Genotypic Characterization of New-onset Type I Diabetes (DIATAG)

Type1diabetes

Belgium
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Pharmacokinetics (PK) and Pharmacodynamics (PD) of Mayne Glucagon for Injection Compared With Glucagen® (Novo Nordisk) in Healthy Volunteers

Hypoglycemia

United Kingdom
Fresenius Kabi USA, LLC

Completed

Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)

Hypoglycemia

United States
University of Chicago

Completed

Incretin Regulation of Insulin Secretion in Monogenic Diabetes

Monogenic Diabetes

United States
Steno Diabetes Center Copenhagen
University of Copenhagen

Completed

Hepatic Metabolic Changes in Response to Glucagon Infusion

Diabetes Mellitus | Non-Alcoholic Fatty Liver Disease | Total Pancreatectomy

Denmark
Sanofi

Withdrawn

A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SAR438544 in Comparison to Glucagon in Type 1 Diabetes Mellitus Patients Under Induced Hypoglycemia

Type 1 Diabetes Mellitus
Legacy Health System
Juvenile Diabetes Research Foundation; Oregon Health and Science University

Completed

Safety Study of Repeated Doses of Glucagon on Animal Starch in the Liver

Type 1 Diabetes Mellitus

United States
Bayer

Active, not recruiting

An Observational Study, Called FINEGUST, to Learn More About How People With Chronic Kidney Disease and Type 2 Diabetes Are Treated and How the Introduction of New Treatment Options, Like Finerenone, Impacts Clinical Practice (FINEGUST)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Japan, Spain, Netherlands, Denmark, United States
Cambridge University Hospitals NHS Foundation Trust

Completed

Haemodynamic Effects of GLP-1 and Glucagon in Healthy Male Volunteers (COCOA)

Cardiovascular Diseases

United Kingdom
Novo Nordisk A/S

Completed

First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People.

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Germany
Karl Neff
University College Dublin

Completed

The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease

Diabetic Kidney Disease

Ireland
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
Inreda Diabetic B.V.

Withdrawn

A Stable Glucagon Analog Administered by a Bihormonal Closed Loop System (STABLE-1)

Diabetes Mellitus, Type 1

Netherlands
Xeris Pharmaceuticals

Completed

Safety and Efficacy of G-Pen Compared to Lilly Glucagon for Hypoglycemia Rescue in Adult Type 1 Diabetics

Hypoglycemia | Diabetes Mellitus, Type 1

United States, Canada
Zealand Pharma

Completed

ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon

Diabetes Mellitus Type 1

Germany
Xeris Pharmaceuticals

Completed

Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D

Hypoglycemia

Canada
University of Florida
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Effects of Exenatide on Motor Function and the Brain

Parkinson's Disease

United States
University of Missouri-Columbia
American Society for Metabolic and Bariatric Surgery

Recruiting

Impact GLP-1 Agonists Following Bariatric

Hypertension | Diabetes Mellitus | Metabolic Syndrome | Morbid Obesity | Obstructive Sleep Apnea of Adult

United States
Hvidovre University Hospital
Technical University of Denmark

Completed

The Impact of Subcutaneous Glucagon Before, During and After Exercise a Study in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Denmark
Hvidovre University Hospital

Completed

Incretin Hormone Antagonism After Bariatric Surgery (INCA-BAR)

Bariatric Surgery

Denmark
Legacy Health System
Juvenile Diabetes Research Foundation; Oregon Health and Science University

Completed

Physiologic Response to Glucagon at Varying Insulin Levels

Type 1 Diabetes Mellitus

United States
Steno Diabetes Center Copenhagen
Herlev Hospital; Technical University of Denmark

Completed

Dual-Hormone Closed-Loop Glucose Control in Adolescents With Type 1 Diabetes (DHCL2021)

Type 1 Diabetes

Denmark
Insel Gruppe AG, University Hospital Bern

Withdrawn

Micro Glucagon During Exercise in Type 1 Diabetes

Hypoglycemia | Type 1 Diabetes

Switzerland
K. Sreekumaran Nair
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

In Vivo Assessment of Cellular Metabolism in Humans

Normal Cellular Metabolism

United States
Eli Lilly and Company
Locemia Solutions ULC

Completed

Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia (AMG102)

Hypoglycemia

Canada
The University of Texas Health Science Center at...
South Texas Veterans Health Care System

Active, not recruiting

Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism (Glucagon)

Insulin Sensitivity

United States
Steven J. Russell, MD, PhD

Completed

Equivalence of A Stable Liquid Glucagon Formulation With Freshly Reconstituted Lyophilized Glucagon

Type 1 Diabetes

United States
Xeris Pharmaceuticals

Completed

Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery

Hyperinsulinemic Hypoglycemia

United States
Zealand Pharma

Completed

Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children

Hypoglycemia

United States, Germany, Slovenia
Christina Kruuse

Recruiting

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke (EGRABIS1)

Ischemic Stroke

Denmark
Joslin Diabetes Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia

Post-bariatric Hypoglycemia

United States

Search clinical trials for: Glucagon receptor antagonist LY2409021

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