Search clinical trials for: HCQ

Total 2223 results

Onconova Therapeutics, Inc.

Completed

Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin

Advanced Solid Tumors

United States
Onconova Therapeutics, Inc.

Completed

Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With Hepatoma

Advanced Solid Tumor | Hepatoma

United States
Northwell Health

Terminated

Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia (ATOMICS)

Metabolic Syndrome

United States
National Cancer Institute (NCI)

Completed

R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer

Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
EMD Serono

Completed

A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation

Infertile Women Undergoing Assisted Reproductive Technology (ART)
Centocor, Inc.

Completed

A Study of the Safety and Efficacy of CNTO 888 in Combination With SoC (Standard of Care) Chemotherapy in Patients With Solid Tumors

Cancer

United States, Spain
Johnson & Johnson Consumer and Personal Products...

Completed

A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting

Enuresis
Fakultas Kedokteran Universitas Indonesia

Completed

Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma

Melasma
Vanderbilt University Medical Center
National Institute of Mental Health (NIMH)

Recruiting

Depressed Mood Improvement Through Nicotine Dosing 3 (DepMIND3)

Depressive Disorder

United States
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...

Malaria

United States
University of Minnesota
National Institute on Drug Abuse (NIDA)

Completed

Innovative Interventions for Smoking Cessation

Tobacco Use Disorder

United States
University of Miami
National Cancer Institute (NCI)

Completed

Smoking Cessation in Hispanic Construction Workers

Smoking Cessation

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Nicotine Addiction Treatment

Nicotine Addiction

United States, Canada
University of California, Los Angeles
University of California

Unknown

Effect of Resistance Training on Tobacco-Related Cardiovascular Disease Risk (START)

Smoking | Cardiovascular Disease Risk

United States
Daniel M. Spielman
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Metastatic Malignant Neoplasm in the Central Nervous System

United States
Ain Shams University

Completed

Erector Spinae Block Using a Dexmedetomidine Versus Magnesium Sulfate as an Adjuvant to Bupivacaine

Postoperative Analgesia

Egypt
Vance Thompson Vision

Unknown

A Randomized, Double-Masked, Controlled, Single Site Investigator Initiated, Exploratory Study of the Midazolam/Ketamine Melt vs Ketamine Melt Alone vs Midazolam Melt Alone in Subjects Undergoing Intraocular Surgery. (MAKER)

Anesthesia

United States
Eye & ENT Hospital of Fudan University

Unknown

Effect of Dexmedetomidine in Preventing Cough and Postoperative Pain After Laryngeal Surgery for Cancer

Laryngectomy; Status

China
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Eribulin Mesylate in Treating Patients With Bladder Cancer That is Advanced or Cannot Be Removed by Surgery

Metastatic Urethral Carcinoma | Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage III Ureter Cancer AJCC v7 | Stage III Urethral Cancer AJCC v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage IV Ureter Cancer AJCC v7 | Stage IV Urethral Cancer AJCC v7 | Ureter Urothelial Carcinoma and other conditions

United States, Canada
Saint-Joseph University

Completed

Dexmedetomidine Versus Propofol in Conjunction With Regional Block for Shoulder Arthroscopy

Sedation | Satisfaction, Personal | Hemodynamic

Lebanon
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

Mechanically Ventilated and Intubated Subjects

United States, Australia, Argentina, Brazil, New Zealand
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

TLR8 Agonist VTX-2337 and Pegylated Liposomal Doxorubicin Hydrochloride or Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Malignant Ovarian Mixed Epithelial Tumor | Ovarian Brenner Tumor | Ovarian Mucinous... and other conditions

United States
Transcept Pharmaceuticals

Completed

Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet

Insomnia

Netherlands
Thomas Jefferson University

Recruiting

Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma and other conditions

United States
Horizon Health Network
McGill University; University of Michigan; Carilion Clinic; Lawson Health Research... and other collaborators

Completed

Narcotic vs. Non-narcotic Pain Study Protocol

Carpal Tunnel

United States, Canada
Women's College Hospital

Completed

The Effect of the Serratus Block on Pain Control After Breast Surgery

Anesthesia

Canada
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

Gemcitabine and Hodgkin's Disease Chemotherapy Followed by Peripheral Blood Stem Cell Rescue for Hodgkin's Disease

Lymphoma | Hodgkin's Lymphoma | Hodgkin Disease

United States
Apotex Inc.

Unknown

A Study Comparing the Bioequivalence of Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray (Apotex, Inc.) to That of Dymista™ Nasal Spray (Meda Pharmaceuticals, Inc.) in the Treatment of Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis
University of California, Los Angeles
Indivior Inc.

Unknown

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

Analgesic Response

United States
Eye Therapies, LLC
ORA, Inc.

Completed

A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)

Allergic Conjunctivitis

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fed Conditions

Healthy

India
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fasting Conditions

Healthy

India
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Ovarian Seromucinous Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Fallopian Tube Mucinous Adenocarcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Endometrioid Adenocarcinoma | Recurrent... and other conditions

United States, Puerto Rico
Armed Forces Institute of Dentistry, Pakistan

Recruiting

Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis (IANB)

Drug Effect | Pulpitis - Irreversible

Pakistan
National Cancer Institute (NCI)

Active, not recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

Hematopoietic and Lymphoid Cell Neoplasm | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Adult Acute Lymphoblastic Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic... and other conditions

United States
Candela Corporation

Completed

Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride (HCL) 1% Cream for Erythematotelangiectatic Rosacea

Erythematotelangiectatic Rosacea

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

Drug Interaction

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

Fatigue | Anemia | Weight Loss | Thrombocytopenia | Fever | Refractory Plasma Cell Myeloma | Lymphadenopathy | Refractory Chronic Lymphocytic Leukemia | Recurrent Plasma Cell Myeloma | Splenomegaly | Recurrent Chronic Lymphocytic Leukemia | Lymphocytosis | Night Sweats

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Regional Anesthesia Versus General Anesthesia

Postoperative Pain | Anesthesia

Italy
Washington University School of Medicine

Completed

Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for Lymphoma

Lymphoma, Non-Hodgkin | Hodgkin Disease

United States
Columbia University
National Institute on Drug Abuse (NIDA)

Completed

Effects of Nicotine Replacement and Repeated Cue Exposure on Cigarette Craving

Tobacco Use Disorder

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms

Cigarette Smoking

United States
Duke University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Effects of Smoking Environments on Craving and Smoking (CameraCue2.0)

Cigarette Smoking

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3

Smoking Cessation | Drug Addiction

United States
University of Maryland, Baltimore
National Institute on Drug Abuse (NIDA)

Completed

Nicotinic Modulation of the Default Network

Magnetic Resonance Imaging | Cognition | Nicotine | Mecamylamine

United States
Washington University School of Medicine
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Genetically Informed Smoking Cessation Trial (GISC)

Smoking Cessation

United States
Assiut University

Not yet recruiting

Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours

Brain Tumor

Egypt
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy (PRIMA)

Recurrent Prostate Carcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Karyopharm Therapeutics Inc

Completed

Selinexor Plus High-Dose Melphalan (HDM) Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Multiple Myeloma

United States

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