Search clinical trials for: HRS -8427

Total 995 results

Grupo Español de Rehabilitación Multimodal

Unknown

Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol (POWER2) (POWER2)

Arthroplasty, Replacement, Knee | Arthroplasty, Replacement, Hip

Spain
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour

Advanced Malignant Tumour
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Bioavailability and Food Effects of HRS-7535 Tablets With Different Formulating Processes in Healthy Subjects

Type 2 Diabetes Mellitus

China
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough

Refractory Chronic Cough

China
5 Santé

Completed

Dyspnea Threshold During 6 Minutes Walk Test (SD6)

COPD

France
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of Intravenous HRS-8427 in the Treatment of Adults With Complicate Urinary Tract Infection, Including Acute Pyelonephritis

Patients With Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP)
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Safety and Pharmacokinetics of HRS-1780 in Healthy Subjects and Subjects With Impaired Renal Function

Chronic Kidney Disease
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Phase I Clinical Study of the Safety， Tolerability，Pharmacokinetics, and Initial Efficacy of HRS-6209 Monotherapy in Patients With Advanced Solid Tumors

Advanced Solid Tumors
Guangdong Hengrui Pharmaceutical Co., Ltd

Recruiting

Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects

Chronic Obstructive Pulmonary Disease

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Phase I Study of HRS-3738 in Recurrent and Refractory Non-Hodgkin's Lymphoma and Multiple Myeloma

Recurrent and Refractory Non-Hodgkin's Lymphoma and Multiple Myeloma

China
Shandong Suncadia Medicine Co., Ltd.

Enrolling by invitation

A Trial of HRS-1358 Tablets in Metastatic or Local Advanced Breast Cancer

Breast Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Fudan University
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Exploratory Clinical Study of HRS-4642 Combined With Adebelimab in the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer

China
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HRS-7450 in Chinese Healthy Volunteers

Cerebral Stroke
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase 1/2 Clinical Study of HRS-4357 in Patients With Advanced Prostate Cancer

Advanced Prostate Cancer
Chengdu Suncadia Medicine Co., Ltd.

Recruiting

Study of HRS-5965 in Healthy Subjects and Subjects With Renal Insufficiency

Glomerulonephritis

China
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Adults With Type 2 Diabetic Kidney Disease

Type 2 Diabetic Kidney Disease
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase I Clinical Study of HRS-9815 for PET/CT Imaging in Patients With Prostate Cancer

Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase I Study of HRS-7053 Injection in the Treatment of Patients With Advanced Malignancies

Advanced Malignant Cancer
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Phase I Clinical Study of HRS-2189 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Chengdu Suncadia Medicine Co., Ltd.

Active, not recruiting

Proof of Concept Study to Assess the Efficacy, Safety of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

China
Mbarara University of Science and Technology
University of Calgary; Alberta Children's Hospital Research Institute; The ELMA... and other collaborators

Not yet recruiting

Impact of New Tools of Simulation-enhanced Peer Learning on Neonatal and Maternal Mortality (Sim-II)

Maternal Mortality | Neonatal Mortality
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, Israel, South Africa
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Obese Subjects .

Overweight and Obesity
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Study of HRS-5041 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Advanced Prostate Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Phase I Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Advanced KRAS G12D Mutant Solid Tumors

China
Istanbul Medipol University Hospital

Completed

Comparison of Different Pain Rating Scales in Patients With Symptomatic Teeth (CoPRS)

Pain | Dental Pain

Turkey
Atridia Pty Ltd.

Completed

A Trial of HRS-7085 Tablet in Healthy Participants With and Without Food Effect.

Inflammatory Bowel Disease

Australia
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Study of HRS-8080 or SHR-A2009 Combined With Anti-tumor Therapy in Patients With Unresectable or Metastatic Breast Cancer

Breast Cancer
Merck Sharp & Dohme LLC

Completed

A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)

Hypertension

United States
Chengdu Suncadia Medicine Co., Ltd.

Recruiting

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Pharmacokinetic and Safety Studies of HRS-7535 in Subjects With Moderate Renal Insufficiency and Healthy Subjects

Type 2 Diabetes
Shandong Suncadia Medicine Co., Ltd.

Recruiting

A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Single- and Multiple- Ascending Dose and Food Effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7535 in Healthy Subjects

Healthy Subjects
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Acute Ischemic Stroke

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Safety and Tolerance of Increased Doses of HRS-5346 Tablets in Healthy Subjects

Lipoprotein Disorder Disease
Guangdong Hengrui Pharmaceutical Co., Ltd

Completed

A Trial of HRS-2261 in Healthy Subjects After Single and Multiple Oral Administration

Chronic Cough

China
Bristol-Myers Squibb
Cardioxyl Pharmaceuticals, Inc

Completed

A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers

Heart Failure
Mahidol University

Unknown

Acid-base Balance in Patients Undergoing Colonoscopy

Colonoscopy | Bowel Preparation
Chengdu Suncadia Medicine Co., Ltd.

Not yet recruiting

A Trial of HRS-5965 Tablets in Primary IgA Nephropathy

Primary IgA Nephropathy
Amgen

Terminated

Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (20170528)

Relapsed/Refractory Acute Myeloid Leukemia (AML)

United States, Korea, Republic of, Australia, Japan, Germany, Canada
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Clinical Study of HRS-8080 in Combination With Dalpiciclib Isethionate Tablets in Patients With Unresectable or Metastatic Breast Cancer

Unresectable or Metastatic Breast Cancer

China
Shandong Suncadia Medicine Co., Ltd.

Active, not recruiting

Safety and Tolerance of Increased Doses of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease

China
Gilead Sciences

Recruiting

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis (SWIFT)

Ulcerative Colitis

United States
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Efficacy and Safety of HRS-1780 Tablets and Henagliflozin Proline Tablets in Patients With Chronic Kidney Disease

Chronic Kidney Disease

China
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Janssen Research & Development, LLC

Completed

A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis (U-POPS)

Psoriasis | Arthritis, Juvenile | Juvenile Psoriatic Arthritis

United States
SiteOne Therapeutics, Inc.
National Institute on Drug Abuse (NIDA)

Terminated

Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ST-2427

Acute, Post-operative Pain

United States

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