Search clinical trials for: histamine dihydrochloride

Total 8468 results

Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Recruiting

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Multiple Sclerosis

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects

Healthy Subjects

Germany
Arrowhead Pharmaceuticals
ICON Clinical Research

Terminated

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Hong Kong
University of California, San Francisco
National Institute of General Medical Sciences (NIGMS)

Completed

Drug-Drug Interaction Study With Metformin and Nizatidine

Healthy

United States
Bayer

Completed

A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects Under Fed Conditions

Clinical Pharmacology

United States
Centre of Postgraduate Medical Education

Completed

Butyrate in Pediatric Inflammatory Bowel Disease

Inflammatory Bowel Diseases
Nathan Kline Institute for Psychiatric Research
Stanley Medical Research Institute

Withdrawn

Sodium Butyrate For Improving Cognitive Function In Schizophrenia

Cognitive Function | Schizophrenic Disorders

United States
Bayer

Completed

A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects

Pain

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants

Healthy Participants

United States
Oriental Neurosurgery Evidence-Based-Study Team

Recruiting

To Evaluate the Therapeutic Efficacy of Hydrated Amniotic Membrane in Promoting Closure of Refractory Macular Holes.

Macular Holes

China
Poxel SA

Completed

Effect of Cimetidine on the PK of Imeglimin

Healthy

United Kingdom
National Institute of Allergy and Infectious Diseases...

Terminated

Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome

Immune Deficiency | JOB's Syndrome | Hyper-IgE Recurrent Infection Syndrome

United States
Maulana Azad Medical College

Completed

A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia

Ventilator Associated Pneumonia | Etiological Organisms | Antimicrobial Drug Susceptibility Pattern | Stress Ulcer Prophylaxis

India
Aalborg University

Completed

Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)

Itch

Denmark
University of South Florida
National Cancer Institute (NCI)

Completed

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Brain Tumor | Cachexia | Myelodysplastic/Myeloproliferative Diseases | Central Nervous System Tumors

United States, Canada, Puerto Rico
University of Chicago

Recruiting

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection (COVID-19)

COVID-19

United States
Sandoz

Completed

Efficacy and Safety of Azelastine +Mometasone , Nasal Spray, 140 mcg + 50 mcg, (Sandoz d.d., Slovenia) and Momat Rino Advance, Nasal Spray, 140 mcg + 50 mcg, (Glenmark, India) Administered as a Monotherapy to Patients With Seasonal Allergic Rhinitis.

Seasonal Allergic Rhinitis

Russian Federation
Sandoz

Completed

Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Bulgaria, Germany, Poland, Moldova, Republic of
Aalborg University

Completed

Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptor

Itch

Denmark
Indira Gandhi Medical College, Shimla

Completed

Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis

Allergic Rhinitis
Hanmi Pharmaceutical Company Limited

Completed

Efficacy/Safety of Pseudoephedrine Plus Levocetirizine Versus Placebo in Patients With Vasomotor Rhinitis

Vasomotor Rhinitis

Korea, Republic of
Sanofi

Completed

Long-Term Safety Performance of Fexofenadine in Asthma

Asthma

United States
Ache Laboratorios Farmaceuticos S.A.

Suspended

Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu

Cold

Brazil
Allergan

Completed

A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis

Conjunctivitis, Allergic

United States
Tanta University

Not yet recruiting

Ketotifen in Non-Alcoholic Fatty Liver Disease Patients

Hepatic Disease
Boston Children's Hospital

Not yet recruiting

Gastrointestinal Dysmotility on Aspiration Risk

Esophageal Motility Disorders | Gastro Esophageal Reflux | Aspiration Pneumonia | Gastric Motor Dysfunction
Dr. Ferrer BioPharma
Clinica Union Medica Del Norte, S.A.S., Santiago, República Dominicana

Active, not recruiting

Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis (ACCROS-R)

COVID-19 | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Respiratory Infection | SARS CoV 2 Infection | COVID-19 Pandemic

Dominican Republic
OBEcure Ltd.

Completed

The Effect of Betahistine on Body Weight in Obese Subjects

Obesity

United States
Medstar Health Research Institute
AstraZeneca

Withdrawn

Total Antioxidant Effects of Esomeprazole in Dyspeptic Patients Receiving Non-steroidal Anti-inflammatory Drugs

Dyspepsia

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Confirmatory Study of TAU-284 in Pediatric Patients With Atopic Dermatitis

Dermatitis | Atopic

Japan
Dr. Reddy's Laboratories Limited

Completed

Bioequivalency Study of Ranitidine Tablets 300 mg of Dr. Reddy's Under Fasting Conditions

Healthy

Canada
Pfizer

Terminated

Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body

Generalized Anxiety Disorder

United States
Assiut University

Not yet recruiting

Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm

Renal Colic | Ureter Stone
Sandoz

Completed

To Demonstrate the Relative Bioavailability Study of Loratadine 10 mg Tablets

Allergy
GlaxoSmithKline

Completed

Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine

Rhinitis, Allergic, Seasonal

United States
Peking Union Medical College Hospital

Unknown

Effectiveness of Qufeng Shengshi Fang on Treatment of Allergic Rhinitis.

Rhinitis, Allergic, Perennial

China
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Completed

TPI 287 in Breast Cancer Metastatic to the Brain

Breast Cancer

United States
Seoul National University Hospital

Recruiting

Modulating Auditory Symptoms and Vertigo of Meniere's Disease by Non-invasive Mastoid Electric Stimulation

Meniere's Disease

Korea, Republic of
Mongi Slim Hospital

Not yet recruiting

Melatonin Versus Hydroxizin for Pre Operative Anxiety in Elderly Patients With Hip Fracture

Preoperative Anxiety
Amy K. Dickey, M.D.
Wake Forest University Health Sciences; University of Texas

Recruiting

Effect of Oral Cimetidine in the Protoporphyrias

Erythropoietic Protoporphyria | X-linked Protoporphyria

United States
Tannaz Armaghnay

Active, not recruiting

Meclizine for Hepatocellular Carcinoma (OPTIM)

Carcinoma, Hepatocellular

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Compare the Pharmacokinetics of Lafutidine and Irsogladine Maleate Tablet

Gastric Ulcer

Korea, Republic of
MEDA Pharma GmbH & Co. KG

Completed

Dymista Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Effect of Loratadine in Lymphangioleiomyomatosis (LORALAM)

Lymphangioleiomyomatosis

Spain
Aalborg University

Completed

Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic Itch

Itch

Denmark
Hanmi Pharmaceutical Company Limited

Completed

PK and Safety Study of HCP1102, HGP0813 and HGP1408

Healthy

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Unknown

AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR)

Allergic Rhinitis | House Dust Mite Allergy

Belgium
Novartis

Completed

Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic Urticaria

Chronic Urticaria

Germany
Sherief Abd-Elsalam

Recruiting

Effect of GABA on ADHD and Seizures in Children With Epilepsy.

Epilepsy

Egypt
RSPR Pharma AB

Completed

RSPR-007 Mannitol Challenge Trial

Asthma

Denmark

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