Search clinical trials for: Hydrochlorthiazide (HCTZ)

Total 557 results

William Beaumont Hospitals
Novartis Pharmaceuticals

Withdrawn

Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics

Hypertension | Diabetes Type 2

United States
Novartis Pharmaceuticals

Completed

A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension

Essential Hypertension

China, Taiwan, Japan, Thailand, Korea, Republic of
The Louis & Rachel Rudin Foundation
Daiichi Sankyo, Inc.

Completed

Renin Profiling in Selection of Initial Antihypertensive Drug

Hypertension

United States
Ospedale San Raffaele

Unknown

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT) (PGX-HT)

Hypertension

Italy
Vanderbilt University Medical Center

Completed

The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial Function

High Blood Pressure

United States
University of Missouri-Columbia

Completed

Optimal HCTZ Cessation for Diagnosis of Hyperparathyroidism

Hyperparathyroidism

United States
University of Florida
Abbott

Completed

INVEST: INternational VErapamil SR Trandolapril STudy

Coronary Artery Disease | Hypertension

United States
Universität des Saarlandes

Completed

Study to Evaluate the Influence of Hydrochlorothiazide on Dermal Photosensitivity and DNA Stability - a Pilot Study (HCTox Study)

Photosensitivity

Germany
Novartis

Completed

A Safety and Efficacy Trial of the Combination of Aliskiren / Hydrochlorothiazide (HCTZ)(300/12.5 mg and 300/25 mg) Compared to Aliskiren 300 mg in Hypertensive Patients

Hypertension

United States, Germany
Novartis

Completed

Safety/Efficacy of Combo Therapy With Aliskiren & Hydrochlorothiazide vs Therapy With Hydrochlorothiazide Alone in Patients With Hypertension

Hypertension

United States, Germany
EMS

Not yet recruiting

Efficacy and Safety of Olmesartan Associated With Chlorthalidone Versus Benicar HCT® in Essential Hypertension Control

Arterial Hypertension
Boehringer Ingelheim

Completed

Relative Oral Bioavailability of Telmisartan / Hydrochlorothiazide (HCTZ) Fixed Dose Combination (FDC) Compared With Its Monocomponents in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Pharmacokinetics of Different Formulations of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ) in Japanese Healthy Male Volunteers

Healthy

Japan
Novartis

Completed

A Clinical Study With Aliskiren Alone or in Combination Therapy With Diuretic Hctz in Venezuelan Hypertensive Patients. (ANDROMEDA)

High Blood Pressure

Venezuela
Novartis Pharmaceuticals

Completed

ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling (ALLMARK)

Hypertension | Left Ventricle Hypertrophy

Spain
Boryung Pharmaceutical Co., Ltd
Chonbuk National University Hospital; Samsung Medical Center; Asan Medical Center and other collaborators

Completed

A Clinical Study to Evaluate Efficacy and Safety of Fimasartan/Hydrochlorothiazide Combination-therapy

Essential Hypertension

Korea, Republic of
AstraZeneca

Completed

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/12.5 and 32/25 mg in Comparison With Candesartan 32 mg

Hypertension

United Kingdom, Germany, Sweden, Estonia, Lithuania, Poland, Ukraine, Denmark, Netherlands, France, Former Serbia and Montenegro
Insel Gruppe AG, University Hospital Bern

Completed

Hydrochlorothiazide for Kidney Stone Recurrence Prevention (NOSTONE)

Nephrolithiasis

Switzerland
University of Texas Southwestern Medical Center
Novartis Pharmaceuticals

Withdrawn

Regression of Fatty Heart by Valsartan Therapy

Metabolic Syndrome | Lipotoxicity

United States
AstraZeneca

Completed

Candesartan Effect in Second Stage Arterial Hypertension (CAESAR)

Stage II Hypertension

Korea, Republic of
Medical University of Vienna

Unknown

Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve

Optic; Neuritis, With Demyelination

Austria
University of South Carolina
Duke University; Kilimanjaro Christian Medical Centre, Tanzania

Completed

Does Preference-based HIV Testing Increase Uptake in High Risk Populations? (DCE-IMPACT)

HIV Testing

United States, Tanzania
Novartis

Completed

Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients

Hypertension

Germany, Switzerland
The First Affiliated Hospital of Soochow University
Zhejiang University; The Second People's Hospital of Huai'an; Soochow Hopes Hematology... and other collaborators

Completed

Haplo HCT vs Haplo-cord HCT for Patients With AML

Acute Myeloid Leukemia | Hematopoietic Stem Cell Transplantation | Haplo-identical Donor | Cord Blood Unit

China
Organon and Co

Completed

LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)

Hypertension
Mylan Pharmaceuticals Inc

Completed

Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg

Healthy

United States
InVasc Therapeutics, Inc.

Completed

Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With Hypertension (NASAA)

Hypertension

United States
Medical Centre Leeuwarden

Completed

Hydrochloorthiazide and Hypernatriaemie

Hypernatraemia

Netherlands
The First Affiliated Hospital of Soochow University
First Affiliated Hospital Xi'an Jiaotong University; Ruijin Hospital; Wuhan Union... and other collaborators

Recruiting

Haplo-cord HCT vs. Haplo-HCT for T-ALL Patients

Haploidentical Hematopoietic Stem Cell Transplantation | Cord Blood | Acute T Cell Lymphoblastic Leukemia

China
Columbia University

Completed

N-of-1 Trials for Blood Pressure Medications in Adults

Hypertension | High Blood Pressure

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Hydrochlorothiazide Tablets 50 mg to Hydrochlorothiazide Tablets 50 mg

Healthy

United States
Hospital Infantil de Mexico Federico Gomez

Unknown

Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria (HIC)

Nephrolithiasis | Hypercalciuria; Idiopathic

Mexico
Merck KGaA, Darmstadt, Germany

Completed

An Observational Study to Evaluate the Efficacy of Lodoz in a Population of Hypertensive Patients (Lodoz OS)

Hypertension

Thailand
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg

Healthy

United States
Merck Sharp & Dohme LLC

Terminated

Dose-ranging Study to Evaluate the Effectiveness and Tolerability of MK0736 in Patients With Type 2 Diabetes Mellitus (T2DM) and Hypertension (0736-007)

Hypertension | Type 2 Diabetes Mellitus
Menarini Group
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Medoxomil 40 mg Monotherapy in Essential Hypertension

Hypertension

Poland, Germany, Israel, Romania, Italy, Denmark, Czechia, Croatia
EMS

Not yet recruiting

Efficacy and Safety of Olmesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control

Essential Arterial Hypertension
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
Takeda

Completed

Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension

Essential Hypertension

Netherlands, Austria, Germany, Poland, United Kingdom
Prevencion

Unknown

INTERVENCION Trial (INTERVENCION)

Blood Pressure, High

Peru
Organon and Co

Completed

SAALT: Subtracting Salt and Adding Losartan Trial (0954A-335)

Hypertension
Sir Mortimer B. Davis - Jewish General Hospital
Novartis Pharmaceuticals

Withdrawn

Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries

Hypertension | Diabetes

Canada
Daiichi Sankyo, Inc.

Completed

Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension

Essential Hypertension

France, Poland, Ukraine, Belgium, Germany, Spain, Bulgaria, Romania, Denmark, Russian Federation, Netherlands, Austria, Slovakia, Czechia
University Hospital, Toulouse
Sanofi; EUCLID Clinical Trial Platform; Cure Parkinson; Réseau NS-Park

Completed

Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson's Disease (LixiPark)

Parkinson Disease

France
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension

Essential Hypertension

United States, Chile, Mexico
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.

Essential Hypertension

United States, Canada
Sanofi

Completed

Efficacy of Irbesartan/Hydrochlorothiazide Versus Valsartan/Hydrochlorothiazide in Mild to Moderate Hypertension (COSIMA2)

Hypertension

India, Malaysia, Philippines, Singapore, Taiwan, Tunisia, Egypt, Korea, Republic of, Hong Kong, Indonesia, Morocco, Pakistan, Thailand, Vietnam
Spanish Society of Internal Medicine

Completed

Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure (CLOROTIC)

Heart Failure

Spain
Boehringer Ingelheim

Completed

Compare Efficacy and Safety of Telmisartan/Hydrochlorothiazide With Telmisartan/Hydrochlorothiazide Plus Amlodipine

Hypertension

Japan

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