Search clinical trials for: Hydrocortisone Modified Release Capsules

Total 274 results

Diurnal Limited

Completed

Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency (CHAMPAIN)

Primary Adrenal Insufficiency

Germany, United Kingdom
Diurnal Limited
National Institutes of Health (NIH)

Completed

Pilot Study to Characterize and Examine the Pharmacokinetics and Efficacy of Chronocort® in Adults With CAH

Congenital Adrenal Hyperplasia | Adrenal Insufficiency | Endocrine Disease

United States
Diurnal Limited

Completed

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia (CONnECT)

Congenital Adrenal Hyperplasia

France, United States, Japan
Diurnal Limited

Enrolling by invitation

Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

United States, France, Japan
GlaxoSmithKline

Completed

First-Time-in-Humans Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of SB756050

Diabetes Mellitus, Type 2

United States
Ulla Feldt-Rasmussen

Unknown

Modified-release Compared to Conventional Hydrocortisone on Diurnal Fatigue in Secondary Hypoadrenalism (PlenadrEMA)

Adrenal Insufficiency
Diurnal Limited
National Institutes of Health Clinical Center (CC)

Completed

Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia

Adrenogenital Syndrome | Congenital Adrenal Hyperplasia | 21-Hydroxylase Deficiency

United States
The Adelaide and Meath Hospital, incorporating...

Unknown

Optimising Steroid Replacement in Patients With Adrenal Insufficiency

Adrenal Insufficiency

Ireland
KalVista Pharmaceuticals, Ltd.

Completed

Phase 1 Crossover Study in Healthy Subjects to Evaluate the PK Profile of KVD824 Following Single and Multiple Doses of Modified Release (MR) Formulations

Hereditary Angioedema

United Kingdom
Shire

Completed

Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency

Adrenal Insufficiency
Boehringer Ingelheim

Completed

Headache Study to Compare Aggrenox Full Dose and Reduced Dose

Cerebrovascular Accident

Taiwan
Vastra Gotaland Region
Sahlgrenska University Hospital, Sweden; The Gothenburg Society of Medicine; Åke... and other collaborators

Not yet recruiting

Treatment Study in Patients Treated With Both Insulin & Hydrocortisone (INSCORT)

Diabetes Mellitus | Adrenal Insufficiency | Polyglandular Autoimmune Syndrome

Sweden
Diurnal Limited
Simbec Research

Completed

Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting Only

Healthy
Pfizer
ViiV Healthcare

Completed

Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine 500 mg in Healthy Subjects

Healthy Volunteer

Belgium
TaiRx, Inc.

Completed

Safety and Pharmacokinetic Study of CVM-1118 Extended-Release in Advanced Cancer Patients

Advanced Cancer

Taiwan
Boehringer Ingelheim

Completed

Pharmacokinetics and Bioavailability Study of Lasolvan Hard Capsules and Effervescent Tablets in Healthy Volunteers

Healthy

Russian Federation
Diurnal Limited
National Institutes of Health (NIH)

Withdrawn

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy (RESTORE)

Congenital Adrenal Hyperplasia

United States
LEO Pharma

Completed

A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy People

Healthy

United Kingdom
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants

Healthy

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
AstraZeneca

Withdrawn

A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects

Healthy Male Subjects | Pharmacokinetics | Safety | Food Effect

United Kingdom
Amgen

Completed

Study to Evaluate Pharmacokinetics of Prototype Modified-Release Formulations Of Apremilast in Healthy Men

Healthy Volunteers

United States
Celero Systems, Inc.

Recruiting

Tolerability of a Modified Health-Dx

Healthy Volunteers

United States
University of Palermo

Completed

Effects of Steroid Replacement Therapy on Metabolic, Cardiovascular and Bone Outcomes in Adrenal Insufficiency

Adrenal Insufficiency
Iladevi Cataract and IOL Research Center

Completed

Prospective Study of Cionni Ring and In-the-bag IOL Implantation for Subluxated Lenses

Lens Subluxation

India
GlaxoSmithKline

Completed

A Study to Compare the Safety and Drug Levels in Blood When Using Various Forms of GSK189075 Given to Healthy Subjects

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
Genzyme, a Sanofi Company

Completed

Study Comparing Thyrogen Versus a Modified Release of Recombinant Human Thyroid Stimulating Hormone

Healthy

United States
University Tunis El Manar

Completed

Salivary Cortisol Measurement in Corticotrope Deficiency Substitution With Hydrocortisone.

Adrenal Insufficiency

Tunisia
Assiut University

Recruiting

Modified Hip Capsular Incision: an Easier Way to do Hip Capsulorrhaphy in Developmental Dysplasia of the Hip (DDH) (DDH)

Developmental Hip Dysplasia

Egypt
University of Ljubljana, Faculty of Medicine

Completed

The Influence of Psychobiological Adversity to Children and Adolescents With Type 1 Diabetes

Stress | Type 1 Diabetes

Slovenia
Pfizer

Completed

A Phase 1 Study To Evaluate The Pharmacokinetics And Safety Of Three Modified Release And One Immediate Release Formulations Of Tofacitinib (CP-690,550) In Healthy Volunteers

Healthy

Singapore
University of Colorado, Denver

Enrolling by invitation

Modifications of Devices for Hip Arthroscopy

Hip Arthroscopy

United States
Mansoura University

Unknown

Evaluation of Posterior Component Separation Modified TAR Technique "Transversus Abdominids Release" in the Treatment of Parastomal Hernia

TAR Technique

Egypt
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020

Enteritis Caused by Radiation

United States
UNION therapeutics

Active, not recruiting

Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis (ADESOS)

Skin Diseases | Atopic Dermatitis

Poland, United States, Hungary, Germany
Calliditas Therapeutics AB

Completed

The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease (NEFIGAN)

Primary IgA Nephropathy

Belgium, United Kingdom, Denmark, Finland, Sweden, Germany, Spain, Italy, Czech Republic, Netherlands
Dr. Reddy's Laboratories Limited

Completed

A Controlled Study to Assess the Efficacy, Safety and Tolerability of Oral DFD-29 Extended Release Capsules

Rosacea

Germany
UNION therapeutics

Completed

Study to Assess the Efficacy and Safety of Orismilast in Psoriasis (IASOS)

Skin Diseases | Psoriasis

United Kingdom, Poland, United States, Germany
Panacea Biotec Ltd

Completed

Bioequivalence Study of Cyclosporine 100mg Capsule Under Fed Condition

Healthy Volunteers

India
University of Roma La Sapienza

Completed

Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM) (DREAM)

Secondary Adrenal Insufficiency | Primary Adrenal Insufficiency

Italy
Lung Biotechnology PBC

Completed

Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Panacea Biotec Ltd

Completed

Bioequivalence Study of Cyclosporine 100mg Capsule Under Fasting Condition

Healthy Volunteers

India
GlaxoSmithKline

Completed

Healthy Volunteer Study Using 3 Different Formulations of Firategrast

Multiple Sclerosis, Relapsing-Remitting

Australia
Astellas Pharma Inc

Completed

A Study to Evaluate and Compare the Efficacy and Safety of FK506MR vs Prograf® in Stable Liver Transplantation Patients

Liver Transplantation

China
Federico II University

Recruiting

Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment (CareOnTIME)

Congenital Adrenal Hyperplasia

Italy
Lung Biotechnology PBC

Completed

An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Ireland
Noorik Biopharmaceuticals AG

Terminated

A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis

Cirrhosis | Ascites | Portal Hypertension

Spain
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Pharmacokinetics, Safety, and Tolerability of SYN-020

Enteritis Caused by Radiation (Disorder)

United States

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