Search clinical trials for: Hyperpolarized (HP) 13C

Total 2162 results

Robert Flavell, MD, PhD
Bristol-Myers Squibb; U.S. Army Medical Research Acquisition Activity

Recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Prostate Cancer | Localized Prostate Carcinoma

United States
Robert Bok, MD, PhD
National Cancer Institute (NCI); National Institute for Biomedical Imaging... and other collaborators

Recruiting

Hyperpolarized 13C Pyruvate as a Biomarker in Advanced Solid Tumors

Advanced Solid Tumor

United States
University of Texas Southwestern Medical Center

Enrolling by invitation

Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate (HPTBI)

Traumatic Brain Injury

United States
University of Texas Southwestern Medical Center

Recruiting

UTSW HP [13-C] Pyruvate Injection in HCM (HPHCM)

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dilated Cardiomyopathy | Cardiomyopathy, Hypertrophic | Heart Failure With Reduced Ejection Fraction | Cardiac Sarcoidosis | Heart Failure With Preserved Ejection Fraction

United States
Chang Gung Memorial Hospital
National Science and Technology Council

Not yet recruiting

Hyperpolarized 13C MRI for Cancer Immunotherapy (DNPSPIO)

Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer

Taiwan
Zhen Wang, MD
American Cancer Society, Inc.

Recruiting

Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors

Renal Cell Cancer | Kidney Neoplasm | Benign Kidney Neoplasm

United States
University of Texas Southwestern Medical Center

Recruiting

Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI) (HPCIM)

Brain Tumor Adult

United States
Susan Chang
National Cancer Institute (NCI)

Active, not recruiting

Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma

Glioblastoma Multiforme (GBM)

United States
Michael Ohliger, MD PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease

NAFLD | Non-Alcoholic Fatty Liver Disease | NASH | Non Alcoholic Fatty Liver | Non Alcoholic Steatohepatitis

United States
Javier Villaneuva-Meyer, MD
National Institute for Biomedical Imaging and Bioengineering (NIBIB); General...

Recruiting

Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma

Meningioma

United States
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy

Cervical Cancer

Taiwan
University of Massachusetts, Worcester

Terminated

Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders

Healthy | Asthma | Cystic Fibrosis | COPD

United States
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Recruiting

Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma

Adult Gliomas, Mixed

United States
Rahul Aggarwal
National Cancer Institute (NCI)

Recruiting

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Prostate Cancer | Advanced Prostate Carcinoma

United States
Children's Hospital Medical Center, Cincinnati

Completed

Imaging and Understanding BOS in Lung Transplantation

Bronchiolitis Obliterans Syndrome

United States
University of Texas Southwestern Medical Center

Enrolling by invitation

Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity (HPCardiotox)

Breast Neoplasms

United States
Ivan de Kouchkovsky, MD
National Cancer Institute (NCI); American Cancer Society, Inc.; National Institute...

Recruiting

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer (pyruvate)

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Thyroid Gland Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

Primary Brain Neoplasm

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Recruiting

Lenvatinib Plus Pembrolizumab in Well Differentiated G3 Neuroendocrine Tumors

Neuroendocrine Tumors | High Grade Neuroendocrine Carcinoma, Any Site | Well-Differentiated Neuroendocrine Carcinoma

United States
University of Kansas Medical Center

Active, not recruiting

Hyperpolarized 129Xe MRI of Survivors of COVID-19

Covid19

United States
University of Maryland, Baltimore

Recruiting

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Glioma

United States
University of Maryland, Baltimore

Recruiting

Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging

Prostate Cancer

United States
Memorial Sloan Kettering Cancer Center
Sunnybrook Health Sciences Centre

Enrolling by invitation

A Study of [13C]Pyruvate as an Imaging Agent for Magnetic Resonance Imaging in Healthy Volunteers

Healthy Volunteers

United States
Mario Castro, MD, MPH

Recruiting

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

Asthma | Cystic Fibrosis | Pulmonary Hypertension | Interstitial Lung Disease | COPD | Pulmonary Infection | Other Lung Disease

United States
Rahul Aggarwal
National Cancer Institute (NCI)

Terminated

Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (HP) (13C) in Castration-Resistant Prostate Cancer (MR)

Prostate Cancer

United States
University of Maryland, Baltimore

Recruiting

Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury

Traumatic Brain Injury | Subarachnoid Hemorrhage

United States
University of Maryland, Baltimore

Not yet recruiting

HP Pyruvate MRI in Cancers (HC-MRI)

Image | Tumors | Warburg Effect

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Predicting Treatment Response in Patients With Prostate Cancer

Prostate Adenocarcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer... and other conditions

United States
University of Kansas Medical Center
Boehringer Ingelheim; Duke University; Children's Hospital Medical Center, Cincinnati

Withdrawn

129Xe Gas Exchange Imaging in IPF and cHP: A Reliability Study

Idiopathic Pulmonary Fibrosis | Hypersensitivity Pneumonitis
Sunnybrook Health Sciences Centre

Recruiting

Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)

Brain Metastases

Canada
Sunnybrook Health Sciences Centre

Terminated

Hyperpolarized Carbon-13 Imaging of Metastatic Prostate Cancer

Prostate Cancer

Canada
Sunnybrook Health Sciences Centre

Withdrawn

Multiparametric MRI for Prostate Cancer Localization and Characterization Using Hyperpolarized Pyruvate (13C) Injection

Prostatic Neoplasms

Canada
University of Texas Southwestern Medical Center

Withdrawn

Metabolic Characteristics of Sarcoma In Vivo Using HP 13-C Magnetic Resonance Spectroscopic Imaging (MRSI) (HPMSS)

Sarcoma, Soft Tissue

United States
University of California, San Francisco
GE Healthcare

Completed

Hyperpolarized Pyruvate Injection in Subjects With Prostate Cancer

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Development and Evaluation of a Quantitative HP MRI for Clinical Prostate Cancer Exam

Prostate Adenocarcinoma

United States
Sunnybrook Health Sciences Centre
Ontario Institute for Cancer Research

Terminated

Hyperpolarized 13C MR Imaging of Lactate in Patients With Locally Advanced Cervical Cancer (LACC) Cervical Cancer

Uterine Cervical Neoplasms

Canada
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C-MRI and Metabolomics for Immune-related Adverse Events (DNP_irAE)

Immune-related Adverse Event

Taiwan
Pamela Munster
Novartis

Withdrawn

Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Solid Tumors, Adult | HPV-Related Squamous Cell Carcinoma | Human Papillomavirus-Related Carcinoma | PIK3CA Mutation-Related Tumors | PIK3CA Mutation | Human Papillomavirus-Related Squamous Cell Carcinoma

United States
Thunder Bay Regional Health Research Institute
Lakehead University; St. Joseph's Care Group; Thunder Bay Regional Health Sciences...

Recruiting

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Obstructive Sleep Apnea | Emphysema | Pulmonary Fibrosis | Lung Cancer | Cystic Fibrosis | Mesothelioma | Pulmonary Hypertension | Interstitial Lung Disease | Pulmonary Embolism | Lung Resection | Lung Transplant | Seasonal Allergies | Lung Infection | Asbes... and other conditions

Canada
Ivan de Kouchkovsky, MD

Not yet recruiting

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Prostate Cancer | High Risk Prostate Carcinoma

United States
University of Massachusetts, Worcester

Completed

Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI

Chronic Obstructive Pulmonary Disease

United States
James Rubenstein
National Cancer Institute (NCI)

Recruiting

Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphoma

Primary CNS Lymphoma

United States
Sunnybrook Health Sciences Centre

Recruiting

Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection

Hypertension | Hypertrophy

Canada
Chang Gung Memorial Hospital

Not yet recruiting

13C Pyruvate DNP MR Spectroscopy for Lymphoma Treatment Response Assessment

Patient Outcome Assessment
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
University of Zurich

Completed

13C Trioctanoate Breath Test as a Measurement of Gastric Fat Volume Emptying (13CTriOBT)

Healthy

Switzerland
Susan Chang
GE Healthcare; Sigma-Aldrich; Phillips-Medisize

Recruiting

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Recurrent WHO Grade III Glioma | WHO Grade III Glioma | WHO Grade II Glioma | Recurrent World Health Organization (WHO) Grade II Glioma

United States
Daniel M. Spielman
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Metastatic Malignant Neoplasm in the Central Nervous System

United States

Search clinical trials for: Hyperpolarized (HP) 13C

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cameroon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations