Search clinical trials for: Hyperpolarized 13C-Pyruvate

Total 2061 results

InventisBio Co., Ltd

Completed

Mass Balance Study of [14C] D-1553 in Chinese Healthy Adult Male Subjects

Mass Balance Study

China
Mitsubishi Tanabe Pharma America Inc.

Completed

Mass Balance Study With MT-7117 (MT-7117 MB)

Healthy Volunteer

United Kingdom
Mitsubishi Tanabe Pharma America Inc.

Completed

Mass Balance Study With MT-8554 (MT-8554 MB)

Healthy Volunteer

United Kingdom
Yale University

Terminated

FAAH Availability in Psychiatric Disorders: A PET Study

Post Traumatic Stress Disorder | Psychosis | Alcohol Use Disorder

United States
Bellus Health Inc

Completed

Mass Balance Recovery, Absorption, Metabolism and Excretion of [14C]-BLU-5937

Healthy

United Kingdom
Celgene

Completed

A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects

Healthy Volunteer

United States
Bayer
Quotient Sciences

Completed

Mass Balance Study of [14C]-NT-814 Oral Suspension in Healthy Male Subjects

Healthy

United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase I, Open-Label Trial to Assess the Absorption, Metabolism, and Excretion of (14C)-OPC-61815 in Healthy Male Japanese Subjects

Healthy Adult Male

United Kingdom
Celgene

Completed

Metabolism and Excretion of [14C]CC-90001 in Healthy Male Subjects

Healthy Volunteer

United States
Resolve Therapeutics

Completed

A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States
Johns Hopkins University

Terminated

Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States

Schizophrenia | Bipolar Disorder

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Completed

ADME Study of [14C]ICP-022 in Healthy Males

Healthy Volunteers

China
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Pfizer

Completed

Single-dose Study of [14C]PF-05221304 Metabolism and Excretion in Healthy Adult Male Subjects

Healthy

United States
University of Michigan

Terminated

Non-Invasive Characterization in Cardiac Sarcoidosis

Cardiac Sarcoidosis

United States
National Institute of Mental Health (NIMH)

Completed

Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People

Pharmacokinetics | Adult

United States
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0980 Following Single Oral Dose Administration in Healthy Postmenopausal Female Subjects

Healthy Volunteer

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 1,Open -Label Study to Assess the Absorption, Metabolism and Excretion of 14C-OPS-2071 Following a Single Oral Dose to Healthy Male Japanese Subjects

Bacterial Enteritis

United Kingdom
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

Bioavailability of [14C]-SK-1404 ADME & IV Microtracer Study

Nocturia

United Kingdom
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation

Constipation

United States
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis

Diabetes Mellitus | Gastroparesis | Diabetes Mellitus Complications

United States
Kissei Pharmaceutical Co., Ltd.

Completed

Study of Absorption, Metabolism and Excretion Following a Single Oral Dose of [14C]KWA-0711 to Healthy Male Subjects

Healthy Male Subject

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-135 and Daclatasvir in Subjects With Genotype 1 Chronic Hepatitis C Chronic Hepatitis C

Hepatitis C | Chronic Hepatitis C | HCV | CHC

New Zealand
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure

Congestive Heart Failure

Bulgaria
FDA Office of Orphan Products Development
Children's Hospital and Health Center

Completed

Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure

Heart Defects, Congenital | Tricuspid Atresia
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioactive ASP1707

Pharmacokinetics of ASP1707

United Kingdom
Massachusetts General Hospital

Terminated

11C Acetate Imaging Post Prostatectomy

Prostate Cancer

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study GSI-136 in Healthy Young and Healthy Elderly Subjects

Healthy | Alzheimer Disease

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety of GSI 136 in Young and Elderly Japanese Males

Healthy | Alzheimer Disease

Japan
Duke University
Boehringer Ingelheim

Recruiting

Xenon MRI and Progressive ILD

Idiopathic Pulmonary Fibrosis | Progressive Pulmonary Fibrosis

United States
Xemed LLC
Children's Hospital of Philadelphia; University of Pennsylvania

Recruiting

Hyperpolarized MRI of Lung Transplants

Lung Transplant Rejection

United States
The Hospital for Sick Children

Recruiting

Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases

Healthy Volunteers

Canada
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Assessment of New Magnetic Resonance Imaging (MRI) Pulse Sequences for Imaging Hyperpolarised Xenon in Lung, Heart and Brain in Volunteers

Healthy Volunteers

United Kingdom
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Boehringer Ingelheim

Completed

Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects

Healthy
Centocor Research & Development, Inc.

Completed

A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic | Lupus Erythematosus, Cutaneous
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Enrolling by invitation

Imaging Inflammation in Alzheimer's Disease

Alzheimer's Disease

United States
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Mass Balance of [14C] SY-5007 in Healthy Adult Male Subjects in China

Healthy Subjects

China
Guangzhou Lupeng Pharmaceutical Company LTD.

Completed

The Mass Balance Study of LP-168 in Healthy Subjects

Clinical Pharmacology

China
Amgen

Active, not recruiting

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

Obesity | Overweight | Type 2 Diabetes Mellitus

United States, Czechia, Taiwan, Canada, Japan, Korea, Republic of, Germany, Hungary, Australia, Hong Kong, Spain, Poland
InventisBio Co., Ltd

Completed

Study in Healthy Adult Female Subjects

Mass Balance Recovery

United States
University of Aarhus

Completed

Validation of 3-[11C]-OHB

Heart Failure | Healthy | Diabetes Mellitus, Type 2

Denmark
Sagimet Biosciences Inc.

Active, not recruiting

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
TenNor Therapeutics Limited

Completed

Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092

Healthy

United States
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
H. Lundbeck A/S

Completed

A Brain Imaging PET Study of [11C]-Lu AF88370 in Healthy Adult Male Participants

Healthy Participants

United Kingdom
H. Lundbeck A/S

Completed

A Brain Imaging PET Study of [11C]-Lu AF90103 in Healthy Adult Male Participants

Healthy Young Men

Sweden
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of Human Substance Balance and Biotransformation of [14C]SHR0302

Rheumatoid Arthritis (RA)

China
Senju Pharmaceutical Co., Ltd.
Quotient Sciences

Completed

Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Spectrum Pharmaceuticals, Inc

Terminated

A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib

Solid Tumor

United States

Search clinical trials for: Hyperpolarized 13C-Pyruvate

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