Search clinical trials for: Hypoxia inducible factor-1 (HIF-1) alpha

Total 4170 results

Indonesia University

Active, not recruiting

Investigating the Impact of Indocyanine Green Titration on Fluorescent Intensity in Free Flap : An Exploration of Alternative Indicators

Temperature Change, Body | Indocyanine Green | Microsurgery | Free Flap

Indonesia
Charite University, Berlin, Germany

Completed

Autonomic Activity During Nap Under Hypoxia (NAPOXIA)

Healthy | Hypoxia | Sleep

Germany
Assiut University

Not yet recruiting

Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α.

Hif-1α Covid-19
Alexandria University

Recruiting

Effect of Low Doses of Hypoxia-inducible Factor- Prolyl Hydroxylase Enzyme Inhibitor Plus Iron in the Treatment of Anemia in Dialysis-dependent Chronic Kidney Disease Patients

Anemia in Dialysis-dependent CKD Patients

Egypt
Hadassah Medical Organization
BioIncept LLC

Unknown

Safety Study of Preimplantation Factor (PIF-1) to Treat Acute Steroid-Resistant Graft-Versus-Host Disease (GVHD) (PIF1GVHD)

Graft Vs Host Disease

Israel
Chulalongkorn University

Completed

Acute Effect of High Intensity Interval Exercise in Patients With Allergic Rhinitis

Allergic Rhinitis

Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults

HIV Infections

United States
VA Office of Research and Development

Completed

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

Sleep Apnea | Age

United States
Università Politecnica delle Marche

Completed

Hyperoxia, Erythropoiesis and Microcirculation in Critically Ill Patient

Respiratory Failure

Italy
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 With or Without HIV-1 SF-2 RGP120 in HIV-1 Uninfected Adult Volunteers

HIV Infections

United States
Barbara Ensoli, MD
Novartis Vaccines

Terminated

A Phase I Safety and Immunogenicity Preventive Vaccine Trial Based on the HIV-1 Tat and V2-deleted Env Proteins (ISS P-002)

HIV Infection

Italy
Prevent Age Resort "Pervaya Liniya"

Recruiting

First Line Prevent Age Study (FLIPS)

Healthy Aging | Healthy Diet | Healthy Lifestyle

Russian Federation
University of Oxford
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Tambua Mapema Plus - to Discover HIV Infection Early and Prevent Onward Transmission (TMP)

HIV Infections

Kenya
Grifols Therapeutics LLC

Completed

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States
University of Sao Paulo General Hospital

Not yet recruiting

Therapeutic Vaccine Based on aDC1 Dendritic Cells for the Control of Viremia After ATI in HIV Infected Individuals

HIV Vaccine

Brazil
VaxGen

Completed

A Study of AIDSVAX B/B and AIDSVAX B/E, Two Possible Vaccines

HIV Infections

United States
Jagiellonian University

Completed

Selective Versus Nonselective Alpha-blockade Prior to Pheochromocytoma Resection - Systematic Review and Meta-analysis

Pheochromocytoma

Poland
VaxGen

Completed

Effectiveness of AIDSVAX B/E Vaccine in Intravenous Drug Users in Bangkok, Thailand

HIV Infections | HIV Seronegativity

Thailand
sigma-tau i.f.r. S.p.A.

Completed

Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanoma

Malignant Melanoma

France, Germany, Hungary, Italy, Poland, Portugal, Spain, Switzerland
VaxGen

Completed

Effectiveness of an HIV Vaccine in HIV-Negative Adults in North America Who Are at Risk of HIV Infection

HIV Infections | HIV Seronegativity

United States, Canada, Netherlands, Puerto Rico
Kamada, Ltd.

Completed

Phase II Study to Evaluate the Efficacy and Safety of Glassia® in Type-1 Diabetes

New Onset Type-1 Diabetes

Israel
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Trial To Evaluate the Safety and Immunogenicity of the UBI HIV-1MN PND Peptide Immunogen, Given by IM Injection, in Combination With the UBI Microparticulate Monovalent HIV-1 MN Branched Peptide Given Orally, in HIV-1 Uninfected Volunteers.

HIV Infections

United States
Wellness Wheel Medical Clinic
University of Saskatchewan; Saskatchewan Health Authority - Regina Area; CIHR...

Recruiting

Syphilis and HIV Point of Care Testing (POCT) in Saskatchewan (SHIVER)

HIV Infections | Syphilis

Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 MN rsgp120 and Bivalent AIDSVAX B/E (HIV-1 MN rgp120/A244 rgp120) in Combination With QS-21 With or Without Alum in Healthy HIV-1 Uninfected Adults

HIV Infections

United States
U.S. Army Medical Research and Development Command
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Not yet recruiting

Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults (RV591)

Human Immunodeficiency Virus

Uganda
Merck Sharp & Dohme LLC

Completed

A Study of Safety, Tolerability, and Immunogenicity of the MRKAd5 Gag/Pol/Nef Vaccine in Healthy Adults (V520-016)

HIV Infections | HIV-1
bioLytical Laboratories

Completed

Testing of INSTI™ HIV-1 Antibody Test Kit in Volunteer Subjects at Risk for HIV Infection

HIV Infections

United States
NEAT ID Foundation
Gilead Sciences

Completed

HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV (HIV CoCo)

COVID-19 | HIV-1-infection

Spain, Germany, Netherlands, United Kingdom, France, Belgium, Italy, Greece
Cepheid

Completed

Clinical Evaluation of the Xpert® HIV-1 VL

Human Immunodeficiency Virus
University of Alberta

Completed

Sex Differences in Sympathetic Activity and Vascular Reactivity During Acute and Chronic Hypoxia.

Vasodilation | Vasoconstriction

Canada
Kamada, Ltd.

Completed

Study of the Safety and Efficacy of Intravenous Alpha-1 Antitrypsin in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Israel
University Of Perugia

Unknown

Thymosin Alfa 1 in Recipients of Allogeneic Hematopoietic Transplantation for Hematological Malignancies

Hematological Malignancies

Italy
Grifols Therapeutics LLC

Completed

Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults (ChAMP)

Alpha 1-Antitrypsin Deficiency

United States
Rabin Medical Center

Unknown

Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant Recipients

Lung Transplantation | Bronchiolitis Obliterable Syndrome
Genexine, Inc.
Symyoo

Completed

Tolerability, Safety and Pharmacokinetics Study of GX-30 in Total Thyroidectomy or Near Total Thyroidectomy Patients

Total Thyroidectomy | Near-total Thyroidectomy

Korea, Republic of
Theravectys S.A.

Completed

Safety, Tolerability and Immunogenicity Induced by the THV01 Treatment in Patients Infected With HIV-1 Clade B and Treated With Highly Active Antiretroviral Therapy (HAART).

HIV Infection

France, Belgium
Universidade Federal do Rio de Janeiro

Completed

High Intensity Interval Training in 1% or 10% Slope (Slope)

Healthy
Grifols Therapeutics LLC

Terminated

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Alpha1-Antitrypsin Deficiency

United States
Second Affiliated Hospital of Soochow University
SciClone Pharmaceuticals

Recruiting

Thymalfasin-based PRaG Mode for Advanced Refractory Solid Tumors

Advanced Solid Tumor | Refractory Tumor

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)

Graft-Versus-Host Disease (GVHD) Acute on Chronic

United States
Novartis Vaccines

Completed

Safety and Immunogenicity (Non-inferiority) of a Purified Chick Embryo Cell Vaccine Vaccine Administered in Two Different Schedules (Conventional Versus Abbreviated Schedule)

Rabies

China
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency (SPARK)

Emphysema | Alpha 1-antitrypsin Deficiency (AATD)

United States
University of Dundee

Recruiting

Bronchiectasis Alpha-1 Augmentation Trial- Modulating Airway Neutrophil Function (BATMAN)

Bronchiectasis Adult

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group; Acute Infection and Early Disease Research Program

Completed

Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection

HIV Infections

United States, American Samoa, Australia
EMD Serono

Terminated

Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis

Arthritis, Psoriatic

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immune Response Study of the Vaccine ALVAC vCP1452 Alone or in Combination With AIDSVAX B/B

HIV Infections

United States
Sun Yat-sen University
SciClone Pharmaceuticals

Completed

The Efficacy and Safety of Ta1 for Sepsis (TESTS)

Sepsis

China
Sun Yat-sen University

Completed

Efficacy of Thymosin alpha1 for Severe Sepsis (ETASS)

Severe Sepsis

China

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