Search clinical trials for: IDX-1197 XELOX

Total 1603 results

Idience Co., Ltd.

Recruiting

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer

Gastric Cancer

Korea, Republic of, United States, China
Idience Co., Ltd.

Completed

Food Effect Study of IDX-1197 in Healthy Subjects

Healthy Male

Korea, Republic of
Idience Co., Ltd.
National OncoVenture; IlDong Pharmaceutical Co Ltd

Completed

Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Korea, Republic of
Idience Co., Ltd.

Active, not recruiting

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS) (VASTUS)

Solid Tumors | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation

Korea, Republic of
Mersana Therapeutics

Completed

A Study of Intravenous XMT-1107 in Patients With Advanced Solid Tumors (XMT-1107)

Neoplasm Metastasis

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Plasmablastic Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell... and other conditions

United States
Celldex Therapeutics

Completed

A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | CD27 Expressing B-cell Malignancies for Example Hodgkin's Lymphoma | Marginal Zone B Cell Lymphoma) | Any T-cell Malignancy | Solid Tumors (Metastatic Melanoma, Renal (Clear) Cell Carcinoma | Hormone-refractory Prostate Adenocarcinoma, Ovarian... and other conditions

United States
Tang-Du Hospital

Recruiting

New Adjuvant Treatment of Locally Advanced Resectable Gastric Cancer With Carelizumab and XELOX

Gastric Cancer

China
Peking University Cancer Hospital & Institute

Not yet recruiting

KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma

HER2-positive Colorectal Cancer | HER2-positive Biliary Tract Cancer

China
Zhejiang Cancer Hospital

Not yet recruiting

Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy

Gastric Cancer

China
Niguarda Hospital

Completed

Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer (NO-CUT)

Colo-rectal Cancer

Italy
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC

Refractory Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8

United States
West China Hospital

Completed

Early Evaluation of Chemosensitivity for Low/Intermediated-risk Mid-low Stage II/III Rectal Cancer

Rectal Cancer

China
Spanish Cooperative Group for the Treatment of...
Sanofi; Roche Pharma AG

Completed

Study of Bevacizumab Alone or Combined With Capecitabine and Oxaliplatin as Support Therapy in Metastatic Colorectal Cancer Patients

Colorectal Cancer

Spain
Sun Yat-sen University

Recruiting

Chemotherapy Alone Versus Surgery Plus Chemotherapy for Distal Gastric Cancer With One Non-curable Factor

Gastric Cancer

China
Shanghai Zhongshan Hospital
Fudan University; RenJi Hospital; Ruijin Hospital; Xinhua Hospital, Shanghai Jiao...

Unknown

Oxaliplatin Plus Capecitabine in the Perioperative Treatment of Locally Advanced Gastric Adenocarcinoma (Neo-Classic)

Gastric Adenocarcinoma

China
Lantheus Medical Imaging

Withdrawn

Trial to Determine Imaging Parameters of LMI1195 in Heart Failure Patients at Low and High Risk of Defibrillator Firing (LMI1195-201)

Heart Failure

United States
Harbin Medical University
Sun Yat-sen University; Fudan University; Cancer Institute and Hospital, Chinese... and other collaborators

Unknown

XELOX and XELIRI Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer

Colorectal Neoplasms | Chemotherapy

China
Lantheus Medical Imaging

Completed

A Phase 1 Trial to Determine Dosimetry, Biodistribution and Safety of LMI 1195-101 in Healthy Subjects and Patients With Heart Failure

Heart Failure

United States
Henan Cancer Hospital

Not yet recruiting

Disitamab Vedotin Combined With Sintilimab and XELOX Perioperative Treatment for Resectable Gastric Caner With HER2 Overexpression

Gastric Cancer

China
Peking University

Recruiting

Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC

HER2-positive Locally Advanced Resectable Gastric Cancer

China
King Abdullah Medical City
King Faisal Specialist Hospital & Research Center; King Saud Medical City; Al...

Recruiting

Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients.

Rectal Cancer

Saudi Arabia
National Cancer Institute, Egypt

Completed

Study of Metronomic Capecitabine and Oxaliplatin Versus XELOX in Egyptian Metastatic Colorectal Cancer Patients

Toxicity | Survival | Clinical Response
Novo Nordisk A/S

Completed

A First Human Dose Trial Investigating Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-1177 in Subjects Being Overweight or With Obesity.

Obesity | Metabolism and Nutrition Disorder

United States
Catholic University of the Sacred Heart

Unknown

Preoperative Downstaging of Extraperitoneal T3 Rectal Cancer: XELOXRT Versus XELACRT. A Multicenter, Phase III Study (INTERACT)

Rectal Cancer

Italy
JS InnoPharm, LLC

Recruiting

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

Melanoma | NSCLC | Solid Tumor

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
MedPacto, Inc.

Completed

Dose Escalation and Proof-of-Concept Studies of Vactosertib (TEW-7197) Monotherapy in Patients With MDS

Myelodysplastic Syndromes

United States
HeNan Sincere Biotech Co., Ltd

Completed

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Merck Sharp & Dohme LLC

Terminated

Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)

Neoplasms | Head and Neck Neoplasms | Colorectal Neoplasms

Australia, Hong Kong
MedPacto, Inc.
National OncoVenture

Completed

First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors

Advanced Stage Solid Tumors

United States
Assiut University

Completed

Uterine Tamponade for Treatment of Primary Postpartum Hemorrhage

Postpartum Hemorrhage
National Cancer Institute (NCI)

Terminated

Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma

Epithelioid Mesothelioma | Sarcomatoid Mesothelioma | Stage IV Pleural Mesothelioma | Recurrent Malignant Mesothelioma | Stage II Pleural Mesothelioma | Stage III Pleural Mesothelioma

United States
Affiliated Cancer Hospital & Institute of Guangzhou...
Zhejiang Cancer Hospital; Guangdong Provincial Hospital of Traditional Chinese... and other collaborators

Unknown

Efficacy of HIPEC in the Treatment of Locally Advanced Gastric Cancer After radIcal Gastrectomy With D2 (EHTLAGCRGD2)

Gastric Cancer

China
PegBio Co., Ltd.
Tigermed Consulting Co., Ltd

Completed

Dose-finding of PB-119 Administered Subcutaneously Once-weekly Versus Placebo in Drug-naïve T2DM Subjects

Type 2 Diabetes Mellitus

China
Third Affiliated Hospital, Sun Yat-Sen University
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Carrelizumab (PD-1) Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer

Locally Advanced Gastric Cancer

China
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Childhood Solid Neoplasm

United States, Canada
MedPacto, Inc.

Completed

Effect of Food on the Pharmacokinetics of TEW-7197 in Healthy Subjects

Healthy Volunteers

Korea, Republic of
Lin Chen

Recruiting

Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer

Efficacy | Safety | HER2 Negative | Locally Advanced Gastric Carcinoma

China
Sun Yat-sen University

Recruiting

Comparing Modified XELOX Plus Sintilimab With Standard XELOX Plus Sintilimab in First-line Treatment for HER2-negative Gastric/Gastroesophageal Junction Adenocarcinoma

Gastric Cancer

China
Fudan University

Unknown

A Phase Ⅱ Study of XELOX Chemotherapy With or Without Surgery of Primary Lesion for Colon Cancer Patients

Metastatic Colon Cancer

China
Tianjin Medical University Cancer Institute and...

Unknown

Trial of Adjuvant Chemotherapy for High Risk Gastric Cancer Patients

Stomach Cancer

China
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

A Clinical Studyf of SHR-1701 or Placebo in Combination With BP102 and XELOX in the First-line Treatment of mCRC

Metastatic Colorectal Cancer (mCRC)

China
Joon Oh Park

Recruiting

Multi-center, Open-label, Phase 1b Clinical Trial to Evaluate the Safety, Tolerability, and Exploratory Efficacy of TEW-7197 in Combination With FOLFOX in Patients With Metastatic Pancreatic Ductal Adenocarcinoma Who Have Failed First-Line Gemcitabine and Nab-Paclitaxel (MP-PDAC-01)

Metastatic Pancreatic Cancer

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...
Xijing Hospital; Peking Union Medical College Hospital; Peking University Cancer... and other collaborators

Active, not recruiting

A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer

Rectal Cancer

China
Cook Group Incorporated

Completed

Treatment of Colonic Obstruction With Cook Evolution® Colonic Stent System

Large Bowel Obstruction | Colonic Obstruction | Colonic Stricture

France, Spain, Denmark, Netherlands, Canada, Italy, United Kingdom
Aramis Biosciences, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

Dry Eye Disease

United States
PegBio Co., Ltd.

Completed

MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PB-119 to Subjects With T2DM

Type2 Diabetes Mellitus

United States
Nationwide Children's Hospital
Thrasher Research Fund

Completed

Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children (Nissle 1917)

Catheter-Related Infections | Recurrent UTIs

United States

Search clinical trials for: IDX-1197 XELOX

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