Search clinical trials for: IMO-8400

Total 2599 results

National Cancer Institute (NCI)

Completed

Bevacizumab and Gemcitabine Combined With Either Cetuximab or Erlotinib in Treating Patients With Advanced Pancreatic Cancer

Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of JNJ-53718678 on the Cardiac Repolarization Interval in Healthy Adult Participants

Healthy

Belgium
Sound Pharmaceuticals, Incorporated
VA Puget Sound Health Care System

Unknown

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Head and Neck Cancer | Lung Cancer | Hearing Loss | Ototoxicity | Tinnitus | Neuropathy

United States
Rockefeller University
Merck Sharp & Dohme LLC; Pfizer; Aaron Diamond AIDS Research Center

Completed

Standard Antiretroviral v. Multi-class Therapy in Acutely HIV-1 Infected Antiretroviral-Naïve Subjects (ADARC 2007-01)

HIV Infections

United States
Fred Hutchinson Cancer Center

Active, not recruiting

Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

Follicular Lymphoma | Acute Myeloid Leukemia | Myelofibrosis | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma and other conditions

United States
Calcutta National Medical College and Hospital

Recruiting

Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages

Miscarriage

India
EpicentRx, Inc.

Completed

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Carcinoma, Non-Small-Cell Lung | Ovarian Epithelial Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States
University of California, Davis

Completed

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

Human Immunodeficiency Virus Infection

United States
AstraZeneca

Completed

A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma

Asthma | Efficacy | Safety

Germany, Bulgaria
Gary Morrow
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Antibiotic Therapy in Preventing Early Infection in Patients With Multiple Myeloma Who Are Receiving Chemotherapy

Multiple Myeloma | Infection

United States, Peru, South Africa
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Atazanavir/Ritonavir and Atazanavir

Healthy Volunteer

United States
National Cancer Institute (NCI)

Withdrawn

A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphoma

Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Metastatic Malignant Neoplasm in the Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues | Metastatic Malignant Neoplasm in the Lung | Metastatic Ewing Sarcoma | Metastatic Malignant Neoplasm in the Bone Marrow | Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone

United States, Canada, Puerto Rico
GlaxoSmithKline

Completed

Single Dose, Pharmacokinetic, Safety, Tolerability and QTc Study of GSK1278863 in Healthy Volunteers

Anaemia

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers

Influenza, Human

United States
Robert J Noveck, M.D.
United States Department of Defense

Completed

A Study to Test the Safety of Combined Dosing With Aminophylline and Ambrisentan in Exercising Healthy Human Volunteers at Simulated High Altitude (GQ02)

Acute Mountain Sickness and Fatigue

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia (ASPIRE)

Schizophrenia

Korea, Republic of, United States, Estonia, Italy, Hungary, Bulgaria, Croatia, France, Poland, Thailand, Puerto Rico, Chile, South Africa, Austria, Belgium
National Institute of Allergy and Infectious Diseases...
University of Rochester

Completed

Study of Immune Responses in Healthy Adults Receiving Live Influenza Virus Vaccines

Influenza, Human

United States
Otsuka Beijing Research Institute

Completed

Aripiprazole IM Depot in the Acute Treatment of Adults With Schizophrenia

Schizophrenia

China
Fundación Pública Andaluza para la gestión de la...
Andaluz Health Service; European Commission

Completed

So-Lo-Mo Intervention Applied to the Smoking Cessation Process (So-Lo-Mo)

Smoking Cessation | Health Behavior | Lifestyle-related Condition
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole (ARRIVE- EU)

Schizophrenia

Belgium, Bulgaria, Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Has Responded to Treatment With Imatinib Mesylate, Dasatinib, or Nilotinib

Recurrent Disease | Adult Acute Lymphoblastic Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Adult B Acute Lymphoblastic... and other conditions

United States
Neurologique Foundation, Inc.
Mallinckrodt

Terminated

Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone (RECLAIM)

Multiple Sclerosis

United States
Brigham and Women's Hospital
Harvard School of Public Health (HSPH)

Active, not recruiting

LungVITamin D and OmegA-3 Trial (lungVITAL) (lungVITAL)

Pneumonia | Asthma | COPD | Pulmonary Function

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Modafinil for Smoked Cocaine Self-Administration

Cocaine Dependence

United States
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital; Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Curative Study of Chinese Traditional Medicine to Treat Lung Cancer (TCM)

Cancer
Janssen R&D Ireland

Completed

TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients

HIV Infections | Acquired Immunodeficiency Syndrome

United States, France, Argentina, South Africa, Thailand
National Cancer Institute (NCI)

Completed

Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors

Malignant Digestive System Neoplasm

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma. (GABRINOX)

Metastatic Pancreatic Adenocarcinoma

France
Northwestern University
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer

Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum

United States
University of Roma La Sapienza

Completed

Comparative Analgesic Effects of Paracetamol/Codeine and Ibuprofen on Pain After Third Molar Surgery

To Control Pain After Third Molar Surgery

Italy
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
University of Illinois at Chicago
National Institute of Mental Health (NIMH)

Completed

Research Investigation of Soy and Estrogen (RISE)

Hot Flashes | Menopause

United States
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Armando Santoro, MD

Unknown

Study of Combination of PIGEV Before Autologous Stem Cell Transplant in Patients With Hodgkin's Lymphoma

Hodgkin's Lymphoma

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Washington University School of Medicine
Celgene

Completed

Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer

Head and Neck Neoplasms

United States
University of Leeds

Completed

Infliximab as Induction Therapy in Early Rheumatoid Arthritis (IDEA) (IDEA)

Rheumatoid Arthritis

United Kingdom
National Cancer Institute (NCI)

Completed

Bevacizumab or Cetuximab And Gemcitabine Hydrochloride, Capecitabine, and Radiation Therapy in Treating Patients With Pacreatic Cancer That Has Been Completely Removed By Surgery

Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Stage IV Lung Cancer AJCC v8 | Metastatic Lung Non-Squamous Non-Small Cell Carcinoma | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

United States
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

PLATFORM Study of Precision Medicine for Rare Tumors

Rare Tumor
ViiV Healthcare

Completed

Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir (CAB) 400 Milligrams Per Milliliter (mg/mL) Formulation in Healthy Adult Participants

HIV Infections

United States, New Zealand
Washington State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

Interaction | Endogenous Biomarkers

United States
University of California, San Francisco

Withdrawn

Advance Provision of Medication Abortion

Early Abortion
Instituto Valenciano de Infertilidad, IVI VALENCIA

Unknown

Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients

Infertility

Spain
GlaxoSmithKline
Shionogi

Completed

Study to Assess Cardiac Conduction of GSK1349572

Healthy Subjects

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Active, not recruiting

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | BRAF NP_004324.2:p.V600X | KRAS wt Allele

United States
Edward Kasaraskis

Completed

Treatment of FUS-Related ALS With Betamethasone - The TRANSLATE Study (TRANSLATE)

Familial Amyotrophic Lateral Sclerosis

United States
VA Office of Research and Development

Completed

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Chronic Kidney Diseases | Gout

United States

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