Search clinical trials for: Immediate release carbidopa/levodopa

Total 418 results

Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted In The Evening or Immediately Following A 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Johnson & Johnson Taiwan Ltd

Terminated

A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia

Schizophrenia

Taiwan
Jaime Moore, MD MPH
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds

Adolescent | Obesity, Morbid | Drug Therapy | Bariatric Surgery | Young Adult

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Prescription Opioid Effects in Abusers Versus Non-Abusers

Substance-Related Disorders | Opioid-Related Disorders

United States
Wayne State University

Recruiting

Cannabidiol, Morphine, Pain (CMP)

Chronic Pain | CBD

United States
Astellas Pharma China, Inc.

Completed

Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients

Kidney Transplant

China
Diurnal Limited
Simbec Research

Completed

Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting Only

Healthy
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following A Low, Medium, And High-Fat Evening Meal As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul; Conselho Nacional de Desenvolvimento... and other collaborators

Recruiting

Methylphenidate in Adults With Attention Deficit/Hyperactivity Disorder

Attention Deficit Disorder With Hyperactivity

Brazil
Sheba Medical Center

Completed

The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD Predominantly Inattentive Type | Attention Deficit/Hyperactivity Disorder Combined Type | ADHD Predominantly Hyperactivity Type | ADHD-not Other Specified

Israel
Theresa Zesiewicz, MD

Terminated

Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome

Restless Leg Syndrome

United States
ViiV Healthcare

Active, not recruiting

Dolutegravir Study in HIV-1 Participants Completing IMPAACT Studies P1093 and P2019

HIV Infections

United States, Thailand, Brazil, South Africa, Zimbabwe, Botswana, Tanzania
Abbott

Completed

A Study Comparing Vicodin® CR and NORCO® to Placebo in Subjects With Acute Pain Following Bunionectomy

Pain
Milton S. Hershey Medical Center
Children's Miracle Network

Terminated

Effects of Evening Dose of Immediate Release Methylphenidate on Sleep in Children With ADHD

Behavioral Insomnia of Childhood | Attention Deficit Disorder With Hyperactivity

United States
NeuroDerm Ltd.

Active, not recruiting

Efficacy, Safety and Tolerability Study of ND0612 vs. Oral Immediate Release Levodopa/Carbidopa (IR-LD/CD) in Subjects With Parkinson's Disease Experiencing Motor Fluctuations (BouNDless)

Parkinson's Disease

United States, Israel, Spain, France, Russian Federation, Austria, Italy, Belgium, Czechia, Hungary, Netherlands, Poland, Portugal, Slovakia, Ukraine, United Kingdom
Bial - Portela C S.A.

Completed

Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon

Parkinson's Disease

Portugal
Massachusetts General Hospital
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

An Open Label Phase I/II Study of Dopamine Transporter Receptor Occupancy With OROS and Immediate Release Methylphenidate as Measured With C-11 Altropane in Human Subjects

Healthy Volunteers

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following Various Sized Lunches As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Acerta Pharma BV
AstraZeneca

Active, not recruiting

Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL (AMPLIFY)

Chronic Lymphocytic Leukemia

United States, Spain, Canada, Italy, Taiwan, Russian Federation, Turkey, Germany, Korea, Republic of, Brazil, Hungary, Poland, China, Sweden, Bulgaria, Israel, United Kingdom, Australia, Saudi Arabia, Austria, France, Czechia, South... and more
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain

Low Back Pain

United States
Boston Pharmaceuticals

Completed

Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects

Healthy Subjects

United Kingdom
IlDong Pharmaceutical Co Ltd

Completed

Clinical Trial to Compare The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg and Immediate Release Formulation

Healthy

Korea, Republic of
Yuhan Corporation

Completed

A Randomized, Active-controlled, Parallel, Open-label, Multicenter, Phase 4 Study to Compare the Efficacy and Safety of Pregabalin Sustained Release Tablet and Pregabalin Immediate Release Capsule in Type II Diabetic Patients With Peripheral Neuropathic Pain

Diabetes Mellitus, Type 2 | Neuropathic Pain

Korea, Republic of
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of A Controlled Release Pregabalin Tablet As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

Belgium
Cephalon

Completed

Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain

Chronic Pain

United States
University Hospital, Strasbourg, France

Recruiting

EEG-MRI Imaging of Methylphenidate Effects in Adult ADHD and Attentional Symptoms in Mood Disorders (ImAteM-TDA)

Adult ADHD | Adult-onset ADHD With Mood Disorder

France
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

Healthy

United States
Boehringer Ingelheim

Completed

Study to Investigate the Regional Drug Absorption of KUC-7483 CL Administered Via an Enterion™ Capsule Compared to an Immediate Release Formulation in Healthy Male Volunteers

Healthy
Cephalon

Completed

Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain

Chronic Pain

United States
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Study to Compare the Safety and Efficacy of Solifenacin With Oxybutynin for the Treatment of Overactive Bladder (VECTOR) (VECTOR)

Overactive Bladder

Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of A Controlled Release Pregabalin Tablet As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule

Healthy

Belgium
Bayer

Completed

Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)

Nasal Congestion
Bial - Portela C S.A.

Completed

Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Carbidopa

Parkinson's Disease (PD)

Canada
Bayer

Recruiting

A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants

Healthy Volunteers | Heartburn | Indigestion | Stomach Acid Related Symptoms | Nocturnal Stomach Acid Related Symptoms

United Kingdom
Yonsei University

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Suvaro®OD Tablet in Patients With Dyslipidemia

Dyslipidemia

Korea, Republic of
Tan Tock Seng Hospital

Completed

Comparison of the Efficacy of Oral Oxycodone and Oral Codeine in the Treatment of Postcraniotomy Pain

Postcraniotomy Pain

Singapore
Mayo Clinic

Completed

Non-intrusive Detection of Temporary Neurologic Impairment By Opioids

Healthy

United States
Allameh Tabatabai University

Completed

Computer-assisted Cognitive Rehabilitation (CACR), Placebo CACR and Psycho-stimulants in the Treatment of ADHD

Attention Deficit Disorder With Hyperactivity

Iran, Islamic Republic of
Seoul National University Bundang Hospital
Chong Kun Dang Pharmaceutical Corp.

Unknown

Immediate Release Versus Slow Release Carvedilol in Heart Failure (SLOW-HF)

Heart Failure With Reduced Ejection Fraction

Korea, Republic of
Supernus Pharmaceuticals, Inc.

Completed

Evaluation of Immediate-Release Viloxazine in Adults With ADHD

Attention-Deficit/Hyperactivity Disorder (ADHD)

United States
HIV Prevention Trials Network
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis for Transgender Women in the US and South America

HIV Prevention

United States, Brazil
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Pain

United States
CTI-1, LLC
GlaxoSmithKline; CTI Clinical Trial and Consulting Services

Completed

A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure (COMPARE)

Congestive Heart Failure

United States
Massachusetts General Hospital
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

A Study of Repeat Dosing of OROS® Methylphenidate Hydrochloride (CONCERTA®) and Immediate Release Methylphenidate Hydrochloride in Healthy Adults

Healthy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Withdrawn

Bioequivalence of a New Sublingual and a Reference Alprazolam Immediate Release Tablet Formulation

Healthy
Beni-Suef University

Unknown

Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy

Effect of Drugs
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Fixed Dose Combination (FDC) Immediate Release (IR) Tablet of Canagliflozin and Metformin Compared to Metformin IR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Bioequivalence

United States
University Hospital, Ghent

Completed

Effect of Strategy for Blood Pressure Control on Cerebral Oxygen Balance During Aortic Coarctation Repair: A Randomized Study

Cerebral Oxygenation

Belgium
Fujian Cancer Hospital

Unknown

Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain

Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naive

3

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