Search clinical trials for: Immuno-oncology (IO) therapy

Total 394 results

ImmuneSensor Therapeutics Inc.

Completed

Safety and Efficacy Study of IMSA101 in Refractory Malignancies

Solid Tumor, Adult

United States
Pfizer

Completed

Master Protocol to Study Treatment Patterns, Medication Adherence, Health and Economic Outcomes and Unmet Needs in RCC

Renal Cell Carcinoma (RCC)

United States
Immune-Onc Therapeutics
Regeneron Pharmaceuticals

Active, not recruiting

First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Immune-Onc Therapeutics

Active, not recruiting

Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors

Solid Tumor, Adult

United States
Salus University

Terminated

Regimens of Intermittent Occlusion Therapy for Amblyopia in Children

Amblyopia

United States
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Peking University

Completed

Study of KN026 Combined With KN046 in Patients With Locally Advanced HER2-positive Solid Tumors

HER2-positive Solid Tumors

China
Salus University
Indiana University

Terminated

Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia

Amblyopia

United States
Immune-Onc Therapeutics

Completed

Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors

Advanced Solid Tumor

China
HCA International Limited

Terminated

Investigating the Efficacy of Hair Sparing Radiotherapy Treatment to the Whole Brain. (SPARE)

Metastatic Brain Cancer

United Kingdom
Stanford University
Varian Medical Systems

Terminated

Real-Time kV Imaging vs. Real-Time 3D Patient Surface Tracking for Head & Neck Cancer

Head and Neck Cancer

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Pembrolizumab Plus CRT Followed by Surgery in Upper ESCC

Esophageal Squamous Cell Carcinoma

China
Peking Union Medical College Hospital
OrigiMed

Recruiting

Real-world Study for Patients With Advanced Hepatobiliary Tumors

Quality of Life | Objective Response Rate | Overall Survival | Progression-free Survival | Disease Control Rate | Duration of Response | Five-year Survival Rate

China
Stanford University

Completed

Pilot Ipilimumab in Stage IV Melanoma Receiving Palliative Radiation Therapy

Melanoma

United States
Second Affiliated Hospital of Soochow University

Not yet recruiting

PRaG Regimens Rechallenge for Patients With Resistance to PD1/PD-L1 Inhibitors in Refractory Advanced Solid Tumors.

Metastatic Solid Tumor
InSightec

Recruiting

Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

Brain Tumor

Korea, Republic of, United States, Canada
Sidney Kimmel Cancer Center at Thomas Jefferson...
Merck Sharp & Dohme LLC

Completed

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

Brain Metastases

United States
The Central Hospital of Lishui City

Not yet recruiting

TACE Combined With "Target Immune" Therapy for First-line Treatment in the Treatment of Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma
Beijing 302 Hospital
Shanghai Public Health Clinical Center; The 6th people's Hospital of Xinjiang... and other collaborators

Recruiting

Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients

AIDS Patients

China
Institut Paoli-Calmettes

Completed

Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid Hemopathy (ALLO-WT1)

Acute Myeloid Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome

France
Stanford University
Aventis Pharmaceuticals

Terminated

Phase II Docetaxel / Carboplatin / XRT + Surgical Resection in Stage III NSCLC

Carcinoma, Non-Small-Cell Lung | Lung Cancer

United States
Wake Forest University Health Sciences

Terminated

The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations

Snake Envenomation

United States
Hunan Province Tumor Hospital

Completed

Outcomes With Immune Checkpoint Inhibitor for Patients With Non-Small-Cell Lung Cancer and Stable Brain Metastases (OMESIA)

Non Small Cell Lung Cancer

China
Cellular Biomedicine Group Ltd.
Fudan University

Unknown

Autologous Immune Cell Therapy in Combination With LHRH-a in Patients With mCRPC

Metastatic Castration-resistant Prostate Cancer

China
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bayer

Completed

Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors

Brain Metastases | Primary Brain Tumors

United States
Pell Bio-Med Technology Co., Ltd.

Recruiting

Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy

Diffuse Large B Cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma | Large B-cell Lymphoma | Follicular Lymphoma Grade 3B | Follicular Lymphoma Grade 3A

Taiwan
Vinmec Research Institute of Stem Cell and Gene...

Completed

Autologous Immune Enhancement Therapy (AIET) for Cancer Patients

Patients With Cancer

Vietnam
National Cancer Institute (NCI)

Terminated

LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer | Adenocarcinoma of Lung

United States
Washington University School of Medicine

Completed

Falls Risk Questionnaire in Older Adults With Cancer

Cancer | Geriatric Assessment

United States
National Taiwan University Hospital

Recruiting

Immune Checkpoint Inhibitor Therapy- Induced Endocrinopathy

Endocrinopathy

Taiwan
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Completed

Application of a Novel Allergen-Specific Immune Signature Directed Approach to Dietary Elimination Therapy in Patients With Eosinophilic Esophagitis (IDiET) (IDiET)

Eosinophilic Esophagitis

United States
First Affiliated Hospital Xi'an Jiaotong University
Fujian Cancer Hospital; Henan Cancer Hospital; The First Affiliated Hospital... and other collaborators

Not yet recruiting

Exploration of the Predictive Marker and Establishment of Predictive Models of Checkpoint Inhibitor Pneumonitis

Pneumonia, Interstitial
Shanghai Pudong Hospital
Duke University

Recruiting

An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis

Metastatic Cancer | Advanced Cancer

China
John L. Villano, MD, PhD

Active, not recruiting

Priming Immunotherapy in Advanced Disease With Radiation

Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer

United States
Guangxi Medical University

Completed

Adjuvant Immune Checkpoint Inhibitors in Postoperative Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Pharmicell Co., Ltd.

Terminated

Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC-PC)

Castration Resistant Prostate Cancer, CRPC

Korea, Republic of
Ottawa Hospital Research Institute
Multiple Sclerosis Scientific Research Foundation

Completed

Autologous Stem Cell Transplant for Multiple Sclerosis (MS/BMT)

Multiple Sclerosis

Canada
Children's Hospital of Fudan University
Fudan University

Completed

Oropharyngeal Administration of Colostrum to Very Low Birth Weight Infants

Infant, Very Low Birth Weight
Medical College of Wisconsin
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck Cancer (DEHART)

Head and Neck Neoplasm

United States
Tongji Hospital
Chongqing University Cancer Hospital; Henan Cancer Hospital; Qilu Hospital of... and other collaborators

Not yet recruiting

A Comparative Study of the Treatment of Real-world Patients With Clear Cell Carcinoma of the Ovary

Ovarian Clear Cell Carcinoma
Xinqiao Hospital of Chongqing

Recruiting

An Observational Clinical Study of Stereotactic Radiotherapy for Advanced Non-Small Cell Lung Cancer With Stable Disease After PD-1 Inhibitor Treatment

Non Small Cell Lung Cancer

China
Canadian Cancer Trials Group
Melanoma and Skin Cancer Trials Limited

Recruiting

Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)

Unresectable/Metastatic Melanoma

Canada, Australia
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade

Immunotherapy | Pneumonitis, Interstitial | Immune-related Adverse Events

Belgium
Sanofi

Completed

A Study to Assess Primarily the Tolerability and Safety of SAR439794 After Repeated Sublingual Daily Administration in Peanut Allergic Adult and Adolescent Patients

Food Allergy

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Withdrawn

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

Head and Neck Cancer
Astellas Pharma Inc

Completed

Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction

Lower Urinary Tract Symptoms | Bladder Outlet Obstruction

United States, Czech Republic, Poland, Hungary, Belgium, Germany
Novartis Pharmaceuticals

Terminated

Phase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway Alterations

Melanoma | Ovarian Cancer | NSCLC | Other Solid Tumors

Italy, Spain, Netherlands, France, Korea, Republic of, Switzerland, Germany, Japan, United States, Canada
Hoosier Cancer Research Network
Merck Sharp & Dohme LLC

Terminated

Study of Pembrolizumab and Concurrent Radiation in Patients With Previously Treated Carcinoma of Unknown Primary

Carcinoma, Unspecified Site

United States
Hoffmann-La Roche
Tempest Therapeutics; Adagene Inc

Recruiting

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers

Korea, Republic of, Taiwan, United States, Israel, China, France, New Zealand
Fudan University

Recruiting

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease | Radiotherapy

China
Incyte Corporation

Completed

A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

Cytokine Release Syndrome

United States

Search clinical trials for: Immuno-oncology (IO) therapy

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