Search clinical trials for: InOrpha Solution

Total 19461 results

Bausch & Lomb Incorporated

Completed

A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution

Ocular Discomfort

United States
Altman Biomedical Consulting Pty. Ltd.

Completed

Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application

Head Lice

Australia
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Leber's Hereditary Optic Neuropathy

United States
Austin Health

Unknown

Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation (CHLORIDE)

Shock | Critical Illness

Australia
Shandong University

Unknown

Different Lugol's Solution Concentration for Image Quality of Esophageal Lesions in Chromoendoscopy With Iodine Staining

Image Quality of Early Esophageal Squamous Neoplasia | Endoscopists'Subjective Assessments

China
Tarsus Pharmaceuticals, Inc.

Recruiting

Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens Wearers (Ariel)

Demodex Blepharitis

United States
Research Insight LLC

Completed

The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study (CLEAR)

Dry Eye

United States
Weill Medical College of Cornell University
Novartis

Withdrawn

Effect of Lifitegrast 5% on Tear Film Markers

Dry Eye | Dry Eye Syndromes | Dry Eyes Chronic

United States
Merck Sharp & Dohme LLC

Completed

The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637)

Dry Eye Disease
Chakshu Research, Inc.

Unknown

Dose-Ranging Study of an Ophthalamic Solution in Patients With Loss of Visual Function Due to Age-Related Nuclear Cataract

Nuclear Cataract

Nepal
Shanghai Medinno Pharmaceutical Technology Co.,...

Recruiting

A Study of MDI-1228_mesylate Ophthalmic Solution in Healthy Adults

Allergic Conjunctivitis

Australia
Uzoma Chinyei Joan

Recruiting

Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.

Effect of Drug

Nigeria
Sight Medical Doctors PLLC
Dompé, US, Inc.

Recruiting

OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate

Neurotrophic Keratitis | Neurotrophic Ulcer | Neurotrophic Corneal Ulcer | Neurotrophic Keratoconjunctivitis

United States
HanAll BioPharma Co., Ltd.
Daewoong Pharmaceutical Co. LTD.

Completed

A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye (VELOS-3)

Dry Eye

United States
Seoul National University Hospital

Completed

Effects of Colloid and Crystalloid on the Microcirculatory Alterations During Off-pump Coronary Artery Bypass Surgery

Cardiac Surgery

Korea, Republic of
Santen Inc.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Santen Inc.

Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SEE-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Shandong University

Completed

Lower Lugol's Solution Concentration on Reducing the Adverse Symptoms of Chromoendoscopy With Iodine Staining

Image Quality | Mucosal Irritation

China
Eskisehir Osmangazi University

Recruiting

TheEffect of a Solution-FocusedApproach on Breastfeeding

Self Efficacy | Breastfeeding | Postpartum

Turkey
GE Healthcare

Not yet recruiting

Feasibility Study Of Ambulatory Monitoring System

Patient Monitoring
B. Braun Ltd. Centre of Excellence Infection Control

Recruiting

HM242-Solution vs Comparator

Venous Leg Ulcer

Italy
Qilu Hospital of Shandong University

Completed

The Effects of Early Enteral Nutrition on Endoscopic Therapy of Esophagogastric Varices in Liver Cirrhosis

Liver Cirrhosis | Esophageal and Gastric Varices

China
Boston Children's Hospital
Beth Israel Deaconess Medical Center; Winchester Hospital

Terminated

Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk

Hypoglycemia | Hypoxic-Ischemic Encephalopathy | Neonatal Abstinence Syndrome

United States
Tigenix S.A.U.

Completed

Adipose Derived Mesenchymal Stem Cells for Induction of Remission in Perianal Fistulizing Crohn's Disease (ADMIRE-CD)

Crohn's Disease

Spain, Belgium, Netherlands, France, Israel, Italy, Austria, Germany
Oxford University Hospitals NHS Trust
University of Oxford

Terminated

Validation of ICG to Identify the Urethra During Rectal Surgery

Rectal Cancer | Surgery | Urethra Injury

United Kingdom
Procter and Gamble

Completed

Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis

Dentin Sensitivity

United States
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
Norgine

Completed

Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus Trisulfate Solution Using 2-Day Split-Dosing Regimen in Adults (NOCT)

Colon Cancer | Colorectal Carcinoma | Colon Cleansing

United States
Molecular Targeting Technologies, Inc.
National Heart, Lung, and Blood Institute (NHLBI); Yale University; University... and other collaborators

Completed

Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients.

Acute Coronary Syndrome

United States
Rothman Institute Orthopaedics
3M

Completed

Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement

Drainage

United States
Moberg Pharma AB

Completed

A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Deformed Nails Resulting From Onychomycosis

Onychomycosis
Capital Clinical Research Associates, LLC

Unknown

Efficacy Study of Botox for Depression

Major Depression

United States
Galapagos NV

Completed

GLPG0259 Solid Formulation Bioavailability and Food Effect

Healthy

Belgium
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Amneal Pharmaceuticals, LLC
CBCC Global Research

Recruiting

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

Ocular Hypertension | Glaucoma, Open-Angle

United States
Mankind Pharma Limited
CBCC Global Research

Completed

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucoma (Glaucoma)

Glaucoma, Open-Angle

United States
Allergan

Completed

Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
TearClear Corp

Active, not recruiting

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure (TC-002-301)

Elevated Intraocular Pressure

United States
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of Bepotastine Besilate Ophthalmic Solution in Seasonal Allergic Conjunctivitis Patients

Allergic Conjunctivitis

United States
Dr. F. Köhler Chemie GmbH

Recruiting

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Kidney Failure | Liver Failure, Chronic | Kidney-Pancreas Failure

Austria
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
Nicholas M Mohr

Completed

Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation

Emergencies | Fluid Loss | Symptom Complex, Triple

United States
NovaBay Pharmaceuticals, Inc.

Completed

Efficacy and Safety of NVC-422 in the Treatment of Adenoviral Conjunctivitis (BAYnovation™)

Adenoviral Conjunctivitis

United States, India, Brazil, Sri Lanka
Boehringer Ingelheim

Completed

Pharmacokinetics and Safety Study of Tipranavir in Combination With Low Dose Ritonavir in Human Immunodeficiency Virus (HIV)-Infected Children

HIV Infections

United States, Argentina, Brazil, Canada, France, Germany, Italy, Mexico, Puerto Rico, Spain
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

Corneal Scar

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Merck Sharp & Dohme LLC

Terminated

A Double-masked, Randomized, Placebo-controlled,Pilot Study of Diquafosol Tetrasodium in Subjects Following Photorefractive Keratectomy (PRK)

Photorefractive Keratectomy
Shanghai Runshi Pharmaceutical Technology Co., Ltd

Not yet recruiting

Relative Bioavailability and Food Effect of SYHA1813 Oral Solution in Healthy Participants

Healthy Participants
Palatin Technologies, Inc

Recruiting

A Phase 3, Multi-Center Study Evaluating PL9643 in Patients With Dry Eye (MELODY-1)

Dry Eye | Dry Eye Syndromes

United States
United Therapeutics

Terminated

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) (PERFECT)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Israel, Argentina, Puerto Rico

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