Search clinical trials for: Interleukin-2 (Proleukin)

Total 16542 results

Novo Nordisk A/S

Completed

Efficacy Study of IL-21 to Treat Metastatic Melanoma

Cancer | Malignant Melanoma

Australia
National University Hospital, Singapore

Completed

A Pilot Study of Autologous Ex Vivo Activated NK Cell Infusion in the Treatment of Metastatic Nasopharyngeal Carcinoma

Metastatic Nasopharyngeal

Singapore
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma | Metastatic Malignant Neoplasm in the Liver

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors

Metastatic Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Cholangiocarcinoma | Metastatic... and other conditions

United States
BGI, China
Wuhan Union Hospital, China

Recruiting

HPV-T in HPV-16 Positive Recurrent or Metastatic Solid Tumors (GI-HPVT-01)

Solid Tumor

China
Peking University People's Hospital

Recruiting

Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial

Systemic Lupus Erythematosus

China
University of Wisconsin, Madison
National Cancer Institute (NCI); EMD Serono

Completed

Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma

Melanoma

United States
Intima Bioscience, Inc.

Not yet recruiting

CISH Inactivated TILs in the Treatment of NSCLC (CheckCell-2)

Carcinoma, Non-Small-Cell Lung | Adenocarcinoma of Lung | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Metastatic Non Small Cell Lung Cancer | Large Cell Lung Cancer

United States
Cytheris SA

Terminated

Study on Interleukin-7 (CYT107) in HIV Patients (Inspire 2)

HIV

United States, Canada
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Interleukin-7 in Treating Patients With Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Hoffmann-La Roche

Completed

A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C

Hepatitis C, Chronic

Belgium, France, Germany, Sweden, Switzerland, Turkey, Greece, Taiwan, Estonia, Slovakia, Italy, Romania, Lithuania, Serbia, Portugal, Egypt, Pakistan, Mexico, Peru, Lebanon, United States, Argentina, Chile, Kuwait, Latvia, Macedonia, The... and more
Centre Leon Berard
Ministry of Health, France; Cytheris, Inc.

Completed

Study Evaluating Impact of IL-7 on CD4 Lymphopenia, Risks of Severe Haematological Toxicity and Tumor Progression in Metastatic Breast Cancer Patients

Metastatic Breast Cancer

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
Celularity Incorporated

Terminated

A Safety Study of Human Cord Blood Derived, Culture Expanded Natural Killer Cell (PNK-007) Infusion With Subcutaneous Recombinant Human IL-2 (rhIL-2) in Adults With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States
Jonsson Comprehensive Cancer Center

Active, not recruiting

Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies

Malignant Neoplasm

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies

Unspecified Adult Solid Tumor, Protocol Specific

United States
National Institute of Allergy and Infectious Diseases...

Completed

Umbrella Study for HIV Infected Adults Enrolled in NIAID-Funded Interleukin-2 Studies

HIV Infections

United States
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
United States Naval Medical Center, San Diego
CEL-SCI Corporation

Terminated

Safety Study of Multikine in the Treatment of Perianal Warts

Condyloma

United States
Wake Forest University Health Sciences
Emory University

Completed

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas (Poly-ICLC)

Brain Tumors

United States
Oslo University Hospital
University of Oslo; Lovisenberg Diakonale Hospital

Withdrawn

Effects of Intraarticular IL1-Ra on Pain and Inflammatory Mediators After Knee Arhroscopy

Knee Injuries

Norway
National Cancer Institute (NCI)

Active, not recruiting

Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Metastatic Kidney Carcinoma

United States
Assiut University

Unknown

Expression of Inflammasomes in HCV Patients (Inflammasome)

Hepatitis C
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Prometheus Laboratories; Miltenyi Biomedicine...

Active, not recruiting

Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

Chronic Graft Versus Host Disease | Chronic GVHD | Complications of Organ Transplant Stem Cells

United States
National Cancer Institute (NCI)

Active, not recruiting

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
University of Wisconsin, Madison

Completed

Eosinophilic Airway Inflammation and Mepolizumab

Asthma

United States
ZymoGenetics

Completed

Study of Interleukin-21 for Metastatic Malignant Melanoma and Metastatic Kidney Cancer

Melanoma | Kidney Neoplasms | Metastases

United States
National Cancer Institute (NCI)

Completed

Randomized Double-Blind Placebo-Controlled Trial Using Recombinant Human Interleukin-10 for Moderate-to-Severe Psoriasis

Psoriasis

United States
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Completed

FT516 and IL2 With Enoblituzumab for Ovarian Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer | Fallopian Tube Adenocarcinoma

United States
Stanley H. Appel, MD

Unknown

T-Regulatory Cells in Amyotrophic Lateral Sclerosis

ALS (Amyotrophic Lateral Sclerosis)

United States
Beijing YouAn Hospital

Unknown

Study of Adoptive Transfer of iNKT Cells Combined With TACE to Treat Advanced HCC

Hepatocellular Carcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy

Stage IV Skin Melanoma

United States
Western Regional Medical Center

Withdrawn

Low-dose Cyclophosphamide and Outpatient IV Interleukin-2 in Metastatic Melanoma

Metastatic Melanoma

United States
National Cancer Institute (NCI)

Completed

Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Recurrent Skin Carcinoma | Stage III Renal Cell Cancer | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Non-Small Cell Lung Carcinoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IV... and other conditions

United States
Sohag University

Not yet recruiting

Assessment of Serum interleukin10 Level in Patients With Immune Thrombocytopenic Purpura at Sohag University Hospital

Immune Thrombocytopenic Purpura

Egypt
Benha University

Completed

Interleukin 33 in Juvenile Idiopathic Arthritis Patients

Juvenile Idiopathic Arthritis

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Carcinoma | HLA-A*0201 Positive Cells Present | COL6A3 Positive | PRAME Positive

United States
Chiron Corporation

Completed

Proleukin in Combination With Rituxan in Patients With Low-Grade Non-Hodgkin's Lymphoma Who Have Previously Failed Rituxan Treatments

Lymphoma, Non-Hodgkin

United States
GC Cell Corporation

Unknown

MG4101 Plus Rituximab Including Lymphodepletion in Patient With r/r NHL B-cell Origin

Refractory Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma

Korea, Republic of
Imperial College London
Medical Research Council

Terminated

Novel Interventions in HIV-1 Infection (IMIRC1003)

HIV-1 Infection

United Kingdom
Masonic Cancer Center, University of Minnesota

Completed

Intraperitoneal Delivery of Adaptive Natural Killer (NK) Cells (FATE-NK100) With Intraperitoneal Int

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Zhujiang Hospital
Shenzhen Geno-Immune Medical Institute

Withdrawn

Interleukin-2 Following 4SCAR19/22 T Cells Targeting Refractory and/or Recurrent B Cell Malignancies

B-Cell Leukemia | B-Cell Lymphoma

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Cord Blood Transplant Recipient

United States
Masonic Cancer Center, University of Minnesota
Incyte Corporation

Completed

Intraperitoneal Natural Killer Cells and INCB024360 for Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma

United States
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Completed

Efficacy and Safety of Addition of IL-2 to Pegylated Interferon Alpha 2a and Ribavirin in HIV/HCV Coinfected Patients

HIV Infections | Chronic Hepatitis C

France
University of Washington
National Cancer Institute (NCI)

Completed

Cyclophosphamide or Denileukin Diftitox Followed By Expanding a Patient's Own T Cells in the Laboratory in Treating Patients With HER-2/Neu Overexpressing Metastatic Breast Cancer, Ovarian Cancer, or Non-Small Cell Lung Cancer Previously Treated With HER-2/Neu Vaccine

HER2-positive Breast Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Recurrent Breast Cancer | Recurrent Ovarian Epithelial Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Recurrent Ovarian Germ Cell Tumor

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Study of Comparing the Efficacy and Safety of Human Umbilical Cord MSCs and Low-dose IL-2 in the Treatment of LN

Systemic Lupus Erythematosus | Lupus Nephritis

China
Chiron Corporation

Completed

Proleukin in Combination With Rituxan in Patients With Intermediate and High-Grade Non-Hodgkin's Lymphoma.

Lymphoma, Non-Hodgkin

United States
University of Florence
Azienda Ospedaliero-Universitaria Careggi

Completed

COVID-19 (SARS-CoV-2) in Urine and Semen

SARS-CoV 2 | Urine | Sexual Function and Fertility Disorders | Semen | Urinary Function Disorders

Italy

Search clinical trials for: Interleukin-2 (Proleukin)

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