Search clinical trials for: Intranasal Ketamine (esketamine)

Total 1842 results

Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
Janssen Research & Development, LLC

Completed

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Drug Abuse

United States
Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Erasmus Medical Center

Enrolling by invitation

Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Complex Regional Pain Syndromes | CRPS (Complex Regional Pain Syndromes)

Netherlands
Psych Atlanta

Completed

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

Treatment Resistant Depression

United States
Medical University of Vienna

Recruiting

Imaging Neural Correlates of Ketamine Using PET/MR (RSKet)

Major Depressive Disorder

Austria
Emory University

Completed

Intranasal (NAS) Ketamine for Cancer Pain

Pain | Cancer

United States
Guangzhou Women and Children's Medical Center

Suspended

Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder

Autism Spectrum Disorder

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants

Healthy

Germany
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Tianjin Medical University General Hospital

Recruiting

S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture

Postoperative Pain | Postoperative Cognitive Dysfunction

China
University of Cincinnati

Unknown

Emergency Ketamine Treatment of Suicidal Ideation

Depression | Suicidal Ideation | Suicidal Impulses

United States
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom
The George Institute
The University of New South Wales

Not yet recruiting

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression (TREK)

Treatment Resistant Depression

Australia
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
Beijing Obstetrics and Gynecology Hospital
Obstetrics & Gynecology Hospital of Fudan University; Beijing Haidian Maternal... and other collaborators

Unknown

The Efficacy and Safety of S-ketamine in Elective Cesarean Section (ES-CS)

Depression | Analgesia | Cesarean Section | Anesthesia | Parturition
Second Affiliated Hospital of Wenzhou Medical University

Recruiting

Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation

Anxiety

China
Centre Hospitalier Universitaire de Charleroi
Centre Hospitalier Universitaire de Liege

Recruiting

Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome. (KESK-FIQ)

Fibromyalgia

Belgium
Eye & ENT Hospital of Fudan University

Recruiting

Comparison of Esketamine-Propofol and Fentanyl-Propofol

Hemodynamics

China
Groupe Oncologie Radiotherapie Tete et Cou
Schering-Plough

Completed

Intravenous Versus Subcutaneous Amifostine in Prevention of Xerostomia After RT for Head and Neck Carcinomas

Head and Neck Cancer

France
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University; Shengjing Hospital; First... and other collaborators

Not yet recruiting

Safety and Efficacy Evaluation of S (+) - Ketamine in Adults

Postoperative Pain | Anesthesia | Adults
Chinese PLA General Hospital
Shanghai Children's Medical Center; Beijing Children's Hospital; Southern Medical... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Delirium | Postoperative Pain | Analgesia | Children | Acute Pain | Depression, Anxiety | Hyperalgesia | S-ketamine | Esketamine

China
Turku University Hospital
University of Turku; University of Helsinki

Completed

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients (DoseRespKeta)

Pain, Postoperative

Finland
Washington University School of Medicine

Completed

Study of Amifostine and IMRT for Protecting Salivary Glands in Head and Neck Cancer

Head and Neck Cancer
Yan Qiu

Unknown

The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) (ECT)

Major Depressive Disorder | Depression, Unipolar | Depression, Bipolar | Manic-Depressive - Now Depressed

China
Lund University

Completed

Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers

Healthy | Abnormal Vascular Flow

Sweden
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Oculeve, Inc.

Completed

A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome

Keratoconjunctivitis Sicca | Dry Eye Syndrome

United States
Eye & ENT Hospital of Fudan University

Completed

S-ketamin Premedication in Pediatric EENT Surgery

Pain, Procedural | Emotions | Separation Anxiety

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-ketamine in Women With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Wuhan Union Hospital, China

Withdrawn

Prophylactic Effects of Esketamine in Surgical Patients

Surgical Injury

China
Kythera Biopharmaceuticals

Completed

Safety Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area in Subjects 65 to 75 Years of Age

Efficacy | Safety | Moderate to Severe Convexity of Submental Fat

United States
Qinghai University
Qinghai Red Cross Hospital

Not yet recruiting

Effects of Esketamine on Postpartum Depression (EEPD)

Postpartum Depression
University of Alabama at Birmingham

Terminated

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

Trauma | Fractures, Closed | Ketamine | Children, Only | Deep Sedation

United States
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Bipolar Depression

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression

Major Depressive Disorder

Poland
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder (DriveSaFe2)

Depressive Disorder, Major

Netherlands
Universidade Federal de Goias
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment (NASO)

Dental Caries | Child Behavior

Brazil
Janssen Research & Development, LLC

Completed

A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants

Healthy

Belgium
The Second Hospital of Anhui Medical University

Recruiting

Effect of Intravenous S-ketamine on Opioid Consumption

Breast Cancer Surgery

China
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
Janssen Research & Development, LLC

Completed

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States
Medical University of Vienna

Unknown

Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter

Depression | Ketamine

Austria
New York State Psychiatric Institute

Terminated

Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD

Obsessive-Compulsive Disorder

United States
Janssen Research & Development, LLC

Completed

A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants

Healthy

United States
Anqing Municipal Hospital

Completed

Esketamine Administration on Recovery Quality After Radical Mastectomy

Esketamine and the Quality of Recovery

China
Juvenile Bipolar Research Foundation

Terminated

Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder (IKBP)

Bipolar Disorder

United States
Grand Hôpital de Charleroi

Recruiting

ESKETamine for FIBromyalgia Treatment (ESKEFIB)

Fibromyalgia

Belgium

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