Search clinical trials for: Intranasal naloxone

Total 746 results

Norwegian University of Science and Technology
Oslo University Hospital; St. Olavs Hospital

Completed

Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital (NINA-1)

Overdose | Drug Abuse

Norway
Oculeve, Inc.

Completed

A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome

Keratoconjunctivitis Sicca | Dry Eye Syndrome

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University Health Network, Toronto

Completed

Regulation of Endogenous Glucose Production by Brain Insulin Action (Nasal insulin)

Insulin Resistance, Diabetes

Canada
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
University of Electronic Science and Technology...

Recruiting

The Effects of Intranasal and Oral Administration of Oxytocin on Responses to Emotional Scenes

Healthy

China
Isfahan University of Medical Sciences

Completed

Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose

Morphinan Opioid Overdose

Iran, Islamic Republic of
University of Maryland, Baltimore

Recruiting

Neural Correlates of Hypoalgesia Driven by Observation

Pain | Virtual Reality | Placebo

United States
Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
German Diabetes Center

Completed

The Effect of Central Insulin on Insulin Sensitivity and Energy Metabolism (Centrin)

Diabetes

Germany
Intersect ENT

Completed

A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic Rhinosinusitis (CONSENSUS II)

Chronic Sinusitis

United States
Bastyr University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Intranasal Glutathione in Parkinson's Disease

Parkinson's Disease (PD)

United States
University of Maryland, Baltimore

Recruiting

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Pain | Virtual Reality | Temporomandibular Disorder | Placebo

United States
Duke University

Withdrawn

Xylitol for Otitis Media

Otitis Media With Effusion
Maria de las Mercedes Perez Rodriguez
James J. Peters Veterans Affairs Medical Center; VISN 3 Mental Illness Research...

Terminated

Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Autism Spectrum Disorder | Borderline Personality Disorder | Schizotypal Personality Disorder | SPD | BPD

United States
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
Oculeve, Inc.

Completed

Tear Production by Nasal Neurostimulation Compared to Active Control

Dry Eye | Dry Eye Syndromes | Keratoconjunctivitis Sicca
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Pherin Pharmaceuticals, Inc.

Completed

Intranasal PH94B for Management of the Symptoms of Generalized Social Phobia (PH94B-SAD)

Social Anxiety Disorder | Social Phobia

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Osivax
Aepodia

Completed

Safety and Immune Response of Increasing Doses of OVX836 After Intramuscular or Intranasal Administrations in Healthy Subjects

Influenza

Belgium
Allergan
ORA, Inc.

Completed

Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry Eye

Dry Eye Syndromes

United States
Allergan

Completed

Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal Neurostimulation

Dry Eye Syndromes

United States
Oculeve, Inc.

Completed

Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator

Keratoconjunctivitis Sicca | Dry Eye Syndrome

United States
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Auris Medical AG

Completed

AM-125 in the Treatment of Acute Peripheral Vertigo Following Neurosurgery (TRAVERS)

Vestibular Vertigo

France
Noveome Biotherapeutics, formerly Stemnion

Completed

Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects

Ocular Hypertension

United States
Oculeve, Inc.

Completed

Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation

Dry Eye Syndromes

United States
Pherin Pharmaceuticals, Inc.

Unknown

Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder (PH80-PMD)

Premenstrual Dysphoric Disorder

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Stimulation Test With Intranasal Glucagon for Corticotroph, Somatotroph and Antidiuretic Axes

Hypopituitarism

Italy
University of Pennsylvania
Allergan

Completed

TrueTear in Sjogren's Disease Patients

Dry Eye Syndromes | Sjogren's Syndrome

United States
Oculeve, Inc.

Completed

Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal Neurostimulator

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
Duke University
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075 (Pharm-OUD-Care)

Opioid Use Disorder

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain

Analgesia | Acute Pain Due to Trauma

Netherlands
Cumbria Partnership NHS Foundation Trust
BeneChill, Inc

Completed

Intranasal Cooling for Cluster Headache and Migraine (COOLHEAD)

Migraine | Cluster Headache

United Kingdom
Center for Vaccine Development - Mali
University College, London; University of Oxford; Public Health England; University... and other collaborators

Recruiting

A Human Controlled Infection Study With Neisseria Lactamica in Malian Adults

Meningitis, Meningococcal

Mali
Tufts Medical Center
Coopervision, Inc.

Withdrawn

Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC) (INTAC)

Neuropathic Pain | Contact Allergy

United States
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States
Finnish Institute for Health and Welfare

Completed

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray (NALPILO)

Naloxone | Gambling | Spray | Opioid

Finland
Icahn School of Medicine at Mount Sinai

Recruiting

The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults

Borderline Personality Disorder

United States
Massachusetts General Hospital
United States Department of Defense

Recruiting

Oxytocin Effects on Bone Metabolism in Children With Autism Spectrum Disorder

Autism Spectrum Disorder | Bone Health

United States
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Bunion Surgery

Hallux Valgus

Search clinical trials for: Intranasal naloxone

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