Search clinical trials for: Intrathecal therapy

Total 20674 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Terminated

Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
Hadassah Medical Organization

Unknown

Gait Characteristics Following a Fall

Motor Impairments | Orthopaedic Injuries | Neurological Conditions

Israel
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Alloantibodies in Pediatric Heart Transplantation

Pediatric Heart Transplantation | Pediatric Heart Transplant Recipients

United States, Canada
Juan J Badimon
AstraZeneca

Completed

Antithrombotic Effects of Ticagrelor Versus Clopidogrel

Acute Coronary Syndrome

United States
Ottawa Heart Institute Research Corporation

Terminated

Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention (AVATAR)

Ventricular Tachycardia | Ventricular Arrhythmia

Canada
University of Leicester

Unknown

Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma

Neuroblastoma

Ireland, United Kingdom, France, Switzerland, Austria, Italy, Spain, Norway, Belgium, Denmark, Israel, Portugal, Sweden
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Unknown

Bevacizumab, Doxorubicin, and Cyclophosphamide Followed By Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients Who Have Undergone Surgery for Early-Stage Breast Cancer

Breast Cancer

United States
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplant

Neuroblastoma
Chimeric Therapies

Completed

Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Interferon Alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma

Melanoma | Skin Cancer

United States
Roswell Park Cancer Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic-Myeloproliferative Diseases

United States
Temple University

Completed

Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
Yale University

Completed

Adjuvant High-Dose, Sequential Chemotherapy in Treating Patients With Resected Breast Cancer

Breast Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

Glioblastoma | Malignant Glioma

United States
Mayo Clinic

Completed

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Unresectable Lung Non-Small Cell Carcinoma | Recurrent Lung Non-Small Cell Carcinoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

Leukemia

United States, Australia, Canada
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Completed

Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

Breast Carcinoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Suspended

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Medulloblastoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Bladder Urothelial Carcinoma | Stage IIIA Bladder Cancer AJCC v8 | Muscle Invasive Bladder Carcinoma | Stage II Bladder Cancer AJCC v8

United States
Vanderbilt University Medical Center
UMC Utrecht

Completed

Decision Support for Intraoperative Low Blood Pressure

Hypotension

United States
Mayo Clinic

Not yet recruiting

Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery

Skin Cancer | Skin Cancer Face | Malignant Cutaneous Adnexal Neoplasm

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States
Hospices Civils de Lyon

Recruiting

Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma (Mel-ImmAdj)

Melanoma

France
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study (SAMURAI)

Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Unresectable Renal Cell Carcinoma

United States
Shandong Provincial Hospital

Recruiting

Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma

Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | B-cell Non Hodgkin Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements

China
Lumosa Therapeutics Co., Ltd.

Recruiting

A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects

Acute Ischemic Stroke

United States
German Breast Group
Pfizer; AMS Advanced Medical Services GmbH

Recruiting

A Randomized, Open-label, Multi-center Phase IV Study Evaluating Palbociclib Plus Endocrine Treatment Versus a Chemotherapy-based Treatment Strategy in Patients With Hormone Receptor Positive / HER2 Negative Breast Cancer in a Real World Setting (GBG 93 - PADMA Study). (PADMA)

Metastatic Breast Cancer

Germany
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1001 PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma

Lymphoma

United States
NRG Oncology
National Cancer Institute (NCI)

Suspended

Niraparib With Standard Combination Radiation Therapy and Androgen Deprivation Therapy in Treating Patients With High Risk Prostate Cancer (NADIR)

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8

Canada, United States
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Stage I Ovarian Cancer AJCC v6 and v7 | Stage IA Fallopian Tube Cancer AJCC v6 and v7 | Stage IB Fallopian Tube Cancer AJCC v6 and v7 | Stage IC Fallopian Tube Cancer AJCC v6 and v7 | Stage II Ovarian Cancer AJCC v6 and v7 | Stage IIA Fallopian Tube Cancer AJCC v6 and v7 | Stage IIB Fallopian... and other conditions

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma

Lymphoma

Canada, United States
Washington University School of Medicine
Celgene

Completed

Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer

Head and Neck Neoplasms

United States
Bayer
Janssen Research & Development, LLC

Terminated

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes (GALILEO)

Transcatheter Aortic Valve Replacement

Belgium, France, Germany, Spain, United States, Switzerland, Canada, Austria, United Kingdom, Korea, Republic of, Denmark, Italy, Netherlands, Poland, Czechia, Sweden, Norway
National Cancer Institute (NCI)
NRG Oncology

Completed

Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer

Ovarian Clear Cell Cystadenocarcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States, Korea, Republic of, Japan
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients

Breast Cancer Nos Premenopausal

China
UNICANCER

Terminated

Combination Chemotherapy Compared With Observation After Surgery in Treating Women With Relapsed Nonmetastatic Breast Cancer

Breast Cancer

France
National Cancer Institute (NCI)

Completed

Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma

Ewing Sarcoma of Bone | Peripheral Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Extraosseous Ewing Sarcoma

United States
Milton S. Hershey Medical Center

Unknown

Busulfan, Melphalan, and Antithymocyte Globulin Followed By Umbilical Cord Blood Transplant in Treating Young Patients With Refractory or Relapsed Malignant Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States
Children's Hospital Los Angeles

Unknown

Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors

Brain and Central Nervous System Tumors

United States, Canada, Australia, Switzerland, New Zealand
Scottish Cancer Therapy Network

Unknown

Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer

Breast Cancer

United Kingdom
European Paediatric Soft Tissue Sarcoma Study Group
Children's Cancer and Leukaemia Group; Dutch Childhood Oncology Group; Italian...

Unknown

Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

Sarcoma

Ireland, United Kingdom, Spain, Belgium, Austria, Denmark, Sweden, Switzerland
Ortho-McNeil Janssen Scientific Affairs, LLC

Withdrawn

Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital

Schizophrenia
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia

Leukemia

United States
National Cancer Institute (NCI)

Terminated

Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer

Breast Neoplasms | Metastases, Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

Cigarette Smoking-Related Carcinoma

United States
University of Leeds
Takeda; Cancer Research UK

Recruiting

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Multiple Myeloma

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Hormone Therapy and Intensity-Modulated Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

Stage IV Prostate Adenocarcinoma AJCC v7 | PSA Level Greater Than Two

United States

Search clinical trials for: Intrathecal therapy

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