Search clinical trials for: irinotecan hydrochloride

Total 8362 results

Per Pfeiffer

Completed

Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable Tumours

Pancreatic Cancer

Denmark
Yonsei University

Completed

A Study of Neoadjuvant Chemoradiotherapy With 5-FU/Leucovorin (FL) vs. TS-1/Irinotecan in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

Korea, Republic of
Clinical Research Center for Solid Tumor, Korea
Seoul National University Hospital

Completed

A Study to Evaluate the Efficacy of Bevacizumab Plus Irinotecan in Recurrent Gliomas

Glioblastoma | Astrocytoma

Korea, Republic of
Boehringer Ingelheim

Completed

Relative Bioavailability of Ambroxol Hydrochloride Lozenge in Comparison to Ambroxol Hydrochloride Syrup (Mucosolvan®) in Healthy Female and Male Volunteers

Healthy
Ruijin Hospital

Recruiting

Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma

Recurrent Glioblastoma

China
Hospital Israelita Albert Einstein
Ministry of Health, Brazil

Recruiting

Brazilian Total Neoadjuvant Therapy Trial (BRAZIL-TNT)

Colorectal Neoplasms

Brazil
Duke University
Genentech, Inc.; Eisai Inc.

Terminated

A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme | Malignant Glioma | Gliosarcoma

United States
SCRI Development Innovations, LLC
Genentech, Inc.

Completed

Irinotecan, Carboplatin, Bevacizumab, and Radiation Therapy in the Treatment of Limited Stage Small Cell Lung Cancer

Lung Cancer | Carcinoma, Small Cell Lung

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group

Completed

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Stage III Colon Cancer | Adenocarcinoma of the Colon

United States, Canada, Puerto Rico
Shanghai Mental Health Center

Not yet recruiting

Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression

Somatic Symptom

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Active, not recruiting

A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata (AA)

Alopecia Areata(AA)

China
Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Russian Federation, Bulgaria, Hungary, Italy, Romania, Serbia
Zhejiang Huahai Pharmaceutical Co., Ltd.

Completed

Tolerability and Pharmacokinetics of Hypidone Hydrochloride in Healthy Subjects

Major Depressive Disorder

China
First Affiliated Hospital of Zhejiang University
Shenyang Sunshine Pharmaceutical Co., LTD.

Unknown

A Pharmacokinetics and Safety Study of Narfurine Hydrochloride Orally Disintegrating Tablets

Improvement of Pruritus in Hemodialysis Patients

China
Sun Yat-sen University

Unknown

Treating Locally Advanced Head and Neck Malignant Tumor With Anlotinib and Chemoradiotherapy

Head and Neck Cancer

China
Xidian University

Unknown

Investigation of the Changes of Brain Structure and Function in Premature Ejaculation Patients and the Effects of Dapoxetine on Central Neural Activity in Premature Ejaculation Patients

Premature Ejaculation

China
National Cancer Institute (NCI)

Completed

Pazopanib in Treating Patients With Malignant Pleural Mesothelioma

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Localized Malignant Mesothelioma

United States
Telik

Completed

Phase 2 Study Comparing Two Dose Schedules of Telintra™ in Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS)

United States
National Cancer Institute (NCI)

Completed

Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma

United States
Federation Francophone de Cancerologie Digestive

Withdrawn

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Colorectal Cancer | Metastatic Cancer

France
UNICANCER

Completed

Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

Colorectal Cancer

France
Peking Union Medical College Hospital

Recruiting

Anlotinib Plus Penpulimab (AK105) for Chemo-refractory Metastatic Colorectal Cancer:ALTER-C003 (ALTER-C003)

Colorectal Cancer

China
Sun Yat-sen University

Recruiting

Anlotinib Combined With Toripalimab in Refractory and Advanced Soft-tissue Sarcoma

Sarcoma,Soft Tissue

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Jaktinib Hydrochloride Cream For Atopic Dermatitis

Atopic Dermatitis

China
SK Chemicals Co., Ltd.
Toray Industries, Inc

Completed

Efficacy and Safety Study of TRK-820 to Treat Conventional-treatment-resistant Pruritus in Patients Receiving Hemodialysis (TRK-820)

Conventional-treatment-resistant Pruritus in Patients Receiving Hemodialysis

Korea, Republic of
Peking Union Medical College Hospital

Not yet recruiting

Study of Anlotinib in Patients With Radioiodine Refractory Differentiated Thyroid Cancer

Locally Advanced or Metastatic Radioiodine-refractory Differentiated Thyroid Carcinoma

China
Institut de Recherches Internationales Servier

Not yet recruiting

Phase 2 Study of Irinotecan Liposome Injection, Oxaliplatin, 5-fluorouracil/Levoleucovorin in Japanese Participants Not Previously Treated for Metastatic Adenocarcinoma of the Pancreas

Metastatic Adenocarcinoma of the Pancreas

Japan
Orexigen Therapeutics, Inc

Terminated

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

Obesity | Overweight

United States
BioCryst Pharmaceuticals

Terminated

Study of Forodesine Hydrochloride in Patients With Relapsed/Refractory Precursor T-Lymphoblastic Leukemia/Lymphoma Who Have Failed Two or More Prior Treatment Regimens

Lymphoma | Leukemia

United States
University of Oklahoma

Terminated

FOLFIRINOX in Patients With Inoperable Pancreatic Cancer

Adenocarcinoma of Pancreas

United States
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Efficacy and Safety of JMT101 in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China
University of Rome Tor Vergata

Completed

Circulating Regulatory Lymphocytes and Outcome of Metastatic Colorectal Cancer Patients

Metastatic Colorectal Cancer

Italy
Eisai Co., Ltd.

Completed

A Double-blind Study of E2020 (Donepezil Hydrochloride) in Patients With Dementia With Lewy Bodies (DLB) (Study E2020-J081-431)

Dementia With Lewy Bodies (DLB)

Japan
St. Jude Children's Research Hospital
Pfizer; Ipsen

Recruiting

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Peripheral Primitive Neuroectodermal Tumor | Recurrent Rhabdoid Tumor | Recurrent... and other conditions

United States, Canada
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Radiotherapy Combined With Irinotecan and Apatinib Followed by PD-1 Antibody and Apatinib for Advanced Solid Tumors

Solid Tumor

China
University of Chicago
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale...

Completed

A Genotype-guided Study of Irinotecan Administered in Combination With 5-fluorouracil/Leucovorin (FOLFIRI) and Bevacizumab in Advanced Colorectal Cancer Patients

Metastatic Colorectal Cancer

United States, Italy
University of Chicago

Terminated

Perioperative FOLFIRINOX for Patients With Resectable Pancreatic Adenocarcinoma: A Pilot Study

Pancreatic Ductal Adenocarcinoma (PDAC)

United States
Fudan University

Not yet recruiting

PD-1 Inhibitor Plus Radiotherapy to Patients With CA19-9-elevated Advanced Pancreatic Cancer (PTCA199-11)

Pancreatic Adenocarcinoma
Rutgers, The State University of New Jersey

Recruiting

Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer (SCOTI)

Rectal Cancer | Colon Cancer

United States
National University Hospital, Singapore
The N.1 Institute for Health (N.1); Cancer Science Institute of Singapore

Not yet recruiting

Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI

Breast Cancer | Solid Tumor | Gastrointestinal Cancer

Singapore
Fudan University

Not yet recruiting

An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

China
Genentech, Inc.

Completed

A Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Without Bevacizumab) in Subjects With Previously Treated Metastatic Colorectal Cancer

Colorectal Cancer

United States
CytoVac A/S

Terminated

Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan

Glioblastoma Multiforme

Denmark
Hokkaido Gastrointestinal Cancer Study Group

Completed

Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer

Colorectal Cancer

Japan
Azienda Ospedaliera Universitaria Integrata Verona
University of Milan

Unknown

Prasugrel in Severe COVID-19 Pneumonia (PARTISAN)

Thrombosis | COVID19

Italy
Southwest Oncology Group
National Cancer Institute (NCI); Roche-Genentech

Completed

S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Colorectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer (SOLARIS)

Colorectal Adenocarcinoma

United States, Puerto Rico
Translational Research Center for Medical Innovation...
Hiroshima Prefectural Hospital; National Hospital Organization Shikoku Cancer...

Completed

Bevacizumab + Triplet Treatment for Untreated With Chemotherapy Metastatic Colorectal Cancer (BeTRI)

Metastatic Colorectal Cancer

Japan
Chugai Pharmaceutical

Unknown

CAPOXIRI+Bevacizumab vs. FOLFOXIRI+Bevacizumab for mCRC (QUATTRO-II)

Metastatic Colorectal Cancer

Japan
University of Chicago
National Cancer Institute (NCI)

Withdrawn

Irinotecan Hydrochloride With FOLFIRI and Cetuximab as First-Line Therapy in Treating Patients With RAS Wild-Type Colorectal Cancer

Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

Italy

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