Search clinical trials for: Irrigation Solution

Total 19678 results

Albany Medical College

Terminated

Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy

Pain, Postoperative

United States
Northwestern University

Completed

Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction

Breast Cancer

United States
Mahidol University

Unknown

Efficacy of Adrenaline in Periarticular Analgesic Injection on Postoperative Pain Control After Total Knee Arthroplasty

Postoperative Pain

Thailand
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Rheumatoid Arthritis

United States, Argentina, Belgium, Brazil, Czechia, Estonia, Finland, Hungary, Israel, Italy, Mexico, Netherlands, Poland, Romania, Russian Federation, Spain, Sweden, United Kingdom, Norway
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis (SARIL-RA-EASY)

RA

United States, Chile, Mexico, Poland, Russian Federation, South Africa
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Pennington Biomedical Research Center
Lipothera

Completed

Association of Beta-2 Adrenergic Agonist and Corticosteroid Injection in the Treatment of Lipomas

Lipoma

United States
Islamic Azad University, Tehran

Completed

Effect of Fentanyl on the Rate of Anesthesia

Painful Irreversible Pulpitis

Iran, Islamic Republic of
Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Oral Doses Of PF-03716539 In Healthy Adult Subjects

Healthy Volunteers

Belgium
Shanghai BDgene Co., Ltd.

Not yet recruiting

A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis

China
Shanghai BDgene Co., Ltd.

Recruiting

A Study of the Safety, Tolerability and Prelinminary Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis

China
Aretaieion University Hospital

Recruiting

Opioid-based Versus Opioid-free Endotracheal Intubation

Anesthesia | Opioid Use | Fentanyl | Analgesic Non-narcotic | Anesthesia Intubation

Greece
Sultan Abdulhamid Han Training and Research Hospital...

Recruiting

Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion (CS)

Subacromial Impingement Syndrome | Central Sensitisation

Turkey
Aretaieion University Hospital

Recruiting

Opioid Sparing Anesthesia in Lumbar Spine Surgery

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Lidocaine | Analgesics | Lumbar Spine Surgery | Pain, Nociceptive

Greece
Minia University

Recruiting

Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study

Pain, Neuropathic

Egypt
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Hemodynamic Optimization of Cerebral Perfusion After Endovascular Therapy in Patients With Acute Ischemic Stroke (HOPE)

Acute Ischemic Stroke

Spain
Aretaieion University Hospital

Recruiting

Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Pain, Neuropathic | Lidocaine | Central Nervous System Depressants | Analgesics | Pain, Nociceptive | Analgesics Non-narcotic

Greece
Children's Hospital of Eastern Ontario
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Alberta Children's Hospital Research Institute and other collaborators

Recruiting

Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study (BIPED)

Bronchiolitis

New Zealand, Canada, Australia
London Vision Clinic

Completed

VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia

Refractive Errors | Myopia

United Kingdom
The University of Texas Health Science Center at...

Completed

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Periodontal Diseases

United States
MorphoSys AG

Active, not recruiting

Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients (frontMIND)

Diffuse Large B-cell Lymphoma

Germany, France, Hungary, Italy, Spain, United States, Austria, Czechia, Australia, Israel, Korea, Republic of, Turkey, Taiwan, Argentina, Canada, Colombia, Ireland, Japan, Malaysia, New Zealand, Philippines, Poland, Romania, Russian... and more
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
Tufts Medical Center

Active, not recruiting

RCT Comparing ESPB Solutions in Breast Surgery

Breast Cancer

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522)

Triple Negative Breast Neoplasms

Brazil, Canada, United States, United Kingdom, Taiwan, Australia, Colombia, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic of, Poland, Portugal, Russian Federation, Singapore, Spain, Sweden, Turkey
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Regione Lombardia

Active, not recruiting

Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Inoperable Patients

Unresectable Sinonasal Tumors

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Regione Lombardia

Active, not recruiting

Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable Patients

Sinonasal Tumors

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis (SariPRO)

Rheumatoid Arthritis

France
Washington University School of Medicine

Completed

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Breast Cancer | Breast Cancer Female | Cancer of Breast

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
ZonMw: The Netherlands Organisation for Health Research and Development; Dutch...

Completed

Adjuvant HIPEC in High Risk Colon Cancer (COLOPEC)

Colorectal Neoplasms | Peritoneal Neoplasms

Netherlands
Jagiellonian University

Completed

Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty

Pain, Postoperative | Knee Osteoarthritis | Arthroplasty Complications | Perioperative Complication

Poland
Yeditepe University

Completed

Pain Relief During Intravenous Cannulation in Pediatric Patients

Local Anesthesia | Cannula Site Pain

Turkey
University of Jordan

Completed

Sedation and Analgesia Using PFK Versus General Anesthesia in Urological Procedures

Urologic Diseases | Anesthesia

Jordan
Genentech, Inc.

Completed

A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

Metastatic Melanoma, BRAF V600 Mutation Positive

Korea, Republic of, Russian Federation, Israel, United States
Abd-Elazeem Abd-Elhameed Elbakry

Completed

Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery

Conscious Sedation

Egypt
Centre Hospitalier Universitaire de la Réunion

Withdrawn

Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome (DEXAPER)

Obstetric Pain | Other Complications of Obstetric Anesthesia - Delivered
Chemische Fabrik Kreussler & CO GmbH
Anfomed GmbH

Completed

Acceptance and Preference of Lidocaine Gel Compared to Injection Anesthesia After Non Surgical Periodontal Treatment

Periodontitis

Germany
Washington University School of Medicine
National Institute on Aging (NIA)

Completed

Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling

Cardiovascular Diseases

United States
Aciont Inc
National Eye Institute (NEI)

Completed

Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis

Non-Infectious Anterior Uveitis

United States
Samara State Medical University

Recruiting

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

Endothelial Dysfunction | Cardiotoxicity | Acute Myeloid Leukemia, Adult

Russian Federation
University of Washington

Unknown

Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone

Substance-Related Disorders

United States
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
Aretaieion University Hospital

Recruiting

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Cholecystectomy | Lidocaine | Central Nervous System Depressants | Analgesics | Analgesic Non-narcotic

Greece
Cerevel Therapeutics, LLC

Completed

A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants

Healthy Volunteers

United States
Institut National de la Santé Et de la Recherche...

Completed

Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)

Corona Virus Infection

Norway, Austria, France, Greece, Portugal, Belgium, Luxembourg
Yuzuncu Yıl University

Completed

Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Nerve Block.

Dexamethasone | Adjuvant | Bupivacaine | Magnesıum Sulphate

Turkey
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Merck Sharp & Dohme LLC

Completed

A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021)

Non-small Cell Lung Carcinoma
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
University of Monastir

Completed

Treatment of Renal Colic in the Emergency Departement (ED).

Renal Colic

Tunisia

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