Search clinical trials for: JAB-8263

Total 2493 results

Catabasis Pharmaceuticals

Completed

Study of Edasalonexent With Midazolam and Deflazacort in Healthy Subjects

Healthy

United States
AstraZeneca

Completed

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Solid Tumors

United States
Celgene

Completed

Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer

Breast Neoplasms | Pancreatic Neoplasms

United States
Sanjiv Sam Gambhir

Terminated

Copper Cu 64-DOTA-B-Fab PET/CT in Imaging Patients With Ovarian and Breast Cancer

Breast Carcinoma | Ovarian Carcinoma

United States
University of California, San Francisco
Celgene Corporation

Completed

Nab-paclitaxel (Abraxane), Gemcitabine, and Capecitabine (Xeloda) for Pancreatic Adenocarcinoma

Adenocarcinoma | Pancreatic Neoplasms | Pancreatic Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Soft Tissues | Metastatic Malignant Neoplasm in the Viscera and other conditions

United States, Puerto Rico
AstraZeneca

Completed

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

Stomach Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Triple Negative Breast Neoplasms | Esophageal Squamous Cell Carcinoma | Carcinoma, Pancreatic Ductal | Carcinoma, Squamous Cell of Head and Neck | Esophagogastric Junction Neoplasms

Korea, Republic of, Japan
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Gliosarcoma | MGMT-Unmethylated Glioblastoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Urethral Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Bladder Adenocarcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Bladder... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Suspended

Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma

United States
Janssen Research & Development, LLC

Completed

A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer

Neoplasms | Neoplasms, Breast | Neoplasms, Ovarian | Advanced or Refractory Solid Malignancies

United States, United Kingdom, Spain, Belgium
The Affiliated Hospital of Qingdao University

Recruiting

Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer (PILOT)

Non-small-cell Lung Cancer (NSCLC)

China
Mostafa Bahaa

Recruiting

Activation of Autophagy and Suppression of Apoptosis by Dapagliflozin Attenuates Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Egypt
UNC Lineberger Comprehensive Cancer Center
AstraZeneca; Rgenix, Inc.

Recruiting

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

Non-Small Cell Lung Cancer

United States
AHS Cancer Control Alberta

Recruiting

Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

Pancreatic Cancer | Cholangiocarcinoma | Biliary Tract Cancer | Hepatocellular Cancer

Canada
University of Cincinnati

Recruiting

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

Pancreas Cancer

United States
UNICANCER
National Cancer Institute, France

Recruiting

PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer (NIRVANA-LUNG)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic | Non-Small Cell Carcinoma of Lung, TNM Stage 4

France, Monaco
Benaroya Research Institute

Recruiting

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

Pancreatic Adenocarcinoma

United States
Uniformed Services University of the Health Sciences
Walter Reed National Military Medical Center

Terminated

Cerebrovascular Reactivity Assessed With fNIRS as a Biomarker of TCVI After Acute Traumatic Brain Injury in Military

Traumatic Brain Injury

United States
New Approaches to Neuroblastoma Therapy Consortium
United Therapeutics

Active, not recruiting

MIBG With Dinutuximab +/- Vorinostat

Neuroblastoma

United States
Novartis Pharmaceuticals

Withdrawn

Study of Efficacy and Safety of Ociperlimab in Combination With Tislelizumab and Platinum-based Doublet Chemotherapy as First-line Treatment for Participants With Locally Advanced or Metastatic NSCLC. (AdvanTIG-306)

Non-small Cell Lung Cancer (NSCLC)
Nektar Therapeutics

Completed

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Breast Cancer | Metastasis

United States, Australia, Belgium, Canada, France, Israel, Italy, Portugal, Spain, United Kingdom
GB006, Inc., a wholly owned subsidiary of Gossamer...
Merck Sharp & Dohme LLC

Terminated

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Renal Cell Carcinoma | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Castration-resistant Prostate Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal... and other conditions

United States, United Kingdom
The Hong Kong Polytechnic University
The University of Hong Kong

Completed

Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression Rate

Myopia

Hong Kong
Washington University School of Medicine
National Cancer Institute (NCI); BioMed Valley Discoveries, Inc

Terminated

BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer | Pancreas Cancer | Cancer of Pancreas | Cancer of the Pancreas

United States
National University Hospital, Singapore

Completed

A Preventive Treatment for Migrant Workers at High-risk of COVID-19

Covid-19

Singapore
Cancer Institute and Hospital, Chinese Academy...
First Affiliated Hospital Xi'an Jiaotong University; Wuhan Union Hospital,... and other collaborators

Unknown

Study of Tislelizumab Plus Chemotherapy vs Chemotherapy as Perioperative Treatment in Participants With HER2 Negative Breast Cancer

HER2-negative Breast Cancer

China
Jenny C. Chang, MD
The Methodist Hospital Research Institute

Completed

T-DM1 With Abraxane and Lapatinib for Metastatic HER2 Positive Breast Cancer (STELA)

Metastatic Breast Cancer

United States
Nathan Bahary, MD

Terminated

Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer

Borderline Resectable Pancreatic Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With Myelofibrosis

Primary Myelofibrosis | Anemia | Secondary Myelofibrosis

United States
Eli Lilly and Company
Incyte Corporation

Completed

A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Hungary, Romania, United States, Czechia, Croatia, Poland, Ukraine, Mexico, India
Novartis Pharmaceuticals

Terminated

An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United Kingdom, Germany, Belgium, Italy, Netherlands
Mayo Clinic
National Cancer Institute (NCI)

Completed

ABI-007 (Nab-Paclitaxel) and Gemcitabine in Treating Women With Metastatic Breast Cancer

Breast Cancer

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Sitagliptin Combined With Gemcitabine and Albumin-bound Paclitaxel in PDAC Patients

PDAC - Pancreatic Ductal Adenocarcinoma
FEMPHARMA Kft.

Recruiting

Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.

Vulvovaginal Candidiasis | Vaginal Yeast Infections

Hungary
The Affiliated Hospital of Xuzhou Medical University

Not yet recruiting

Envafolimab Combined With Endostar and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
University of Kansas Medical Center

Recruiting

Mitigating the Pro-inflammatory Phenotype of Obesity (MAPLE)

Obesity | Diabetes | Insulin Resistance | Blood Pressure | Diuretics Drug Reactions | Sympathetic Nerve Activity

United States
Guangdong Provincial People's Hospital

Recruiting

The Efficacy and Safety of Sintilimab Plus Anlotinib Combined With Chemotherapy as Neoadjuvant Therapy in TNBC (NeoSACT)

Triple Negative Breast Cancer

China
Guangdong Association of Clinical Trials

Not yet recruiting

Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC

Non-Small-Cell Lung Cancer
Shanghai Chest Hospital

Recruiting

Tislelizumab Combined With Chemotherapy With or Without Bevacizumab in TKI-Resistant EGFR-Mutated Non-squamous NSCLC

Non Small Cell Lung Cancer

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer

Recurrent Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | Metastatic Breast Carcinoma | Locally Advanced Breast Carcinoma

United States
University of California, Irvine
Jacobs Foundation

Completed

SSIs for Mental Health and Loneliness

Depression | Stress | Anxiety | Loneliness | Distress, Emotional | Mental Health Issue

United States
Chimerix
Translational Drug Development

Terminated

Phase 2 Study to Assess the Efficacy & Safety of Gemcitabine + Nab Paclitaxel With or Without Dociparstat in Metastatic Pancreatic Cancer Patients (PGPC1)

Metastatic Pancreatic Cancer

United States
Seoul National University Hospital

Completed

Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers

Gastroesophageal Reflux Disease

Korea, Republic of
Eli Lilly and Company

Terminated

A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Puerto Rico
Radboud University Medical Center
St. Antonius Hospital

Completed

Fluconazole Pharmacokinetics, Including Bioavailability, in Obese Subjects After an Intravenous and Oral Administration (FOLIA)

Obesity | Candidiasis | Invasive Fungal Infections | Fluconazole

Netherlands
German Breast Group
Celgene; Amgen

Completed

Study of Nab-Paclitaxel in High Risk Early Breast Cancer (GAIN-2)

Breast Cancer

Germany
AstraZeneca

Completed

Phase Ib/II Study of MEDI4736 Evaluated in Different Combinations in Metastatic Pancreatic Ductal Carcinoma

Metastatic Pancreatic Ductal Adenocarcinoma

United States, United Kingdom
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Reduced Oxidant or Nicotine Content Cigarettes in Smokers

Tobacco Smoking Behavior

United States
Daewoong Pharmaceutical Co. LTD.

Unknown

A Single-dose, Randomized, Two-period, Two-treatment, Two-sequence, Crossover Bioequivalence Study on a Olostar Tab Versus Two Co-administered Reference Products Olmesartan Medoxomil and Rosuvastatin Calcium in Healthy Volunteers

Healthy

Search clinical trials for: JAB-8263

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