Search clinical trials for: JAK Inhibitor

Total 65163 results

Hospices Civils de Lyon

Not yet recruiting

Maxillofacial Rehabilitation Using Motor Imagery vs Sham After Orthognathic Surgery (MAXIMAND)

Maxillofacial Abnormalities

France
University Hospital, Ghent

Completed

Immediate Loading of Implants in Totally Edentate Upper and Lower Jaw. Trial to Evaluate Survival of the Implants and Bridges, Quality of Prosthetic Work and Patient Satisfaction

Dental Implants

Belgium
Takeda

Completed

TAK-648 Multiple-Rising Dose Study in Healthy Japanese Participants and Non-Japanese Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Takeda

Completed

An [^11C]T-773 Positron Emission Tomography (PET) Study to Determine Phosphodiesterase10A Occupancy by TAK-063

Healthy Volunteers
Mitsubishi Tanabe Pharma Corporation

Completed

A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia

Chronic Kidney Disease | Hyperphosphatemia | Dialysis

United States, Puerto Rico
Takeda

Completed

Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.

Chronic Insomnia

United States
Takeda

Completed

Efficacy and Safety of Ramelteon on Chronic Insomnia

Chronic Insomnia
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) for TAK-906 in Participants With Diabetes Mellitus and Gastroparesis (DG) or With Idiopathic Gastroparesis (IG)

Diabetes Mellitus and Gastroparesis, Idiopathic Gastroparesis

United States
Takeda

Completed

Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"

Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other

Japan
Dolorgiet GmbH & Co. KG
d.s.h. statistical services GmbH; CenTrial GmbH

Completed

Study Whose Purpose is to Find an Optimal Dose for the Treatment With AK 3012 in Patients With Actinic Keratosis

Actinic Keratosis Olsen Grade I/II

Germany
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Zhou Fuxiang

Not yet recruiting

Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies

Stage IV Pancreatic Cancer | Hepatocellular Carcinoma , Cholangiocarcinoma

China
Takeda

Recruiting

A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Colorectal Cancer | Non-small Cell Lung Cancer (NSCLC) | Squamous Cell Cancer of Head and Neck (SCCHN)

Korea, Republic of, United States, Australia
University of Toledo Health Science Campus

Active, not recruiting

Models for Improving Operating Room Productivity: Delays, Cancellations and Pre-admission Testing

Other Surgical Procedures

United States
Takeda

Enrolling by invitation

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Alpha1-Antitrypsin Deficiency

United Kingdom, Germany, United States, Austria, Portugal
Takeda

Available

Post Trial Access Program of TAK-577 for Von Willebrand Disease (VWD)

Von Willebrand Disease (VWD)
Millennium Pharmaceuticals, Inc.

Completed

Safety Study of TAK-700 in Subjects With Prostate Cancer. (TAK-700)

Prostatic Neoplasms

United States
Takeda

Completed

A Single- and Multiple-Dose Study of the Pharmacokinetics of TAK-491 in Healthy Chinese Participants

Healthy Volunteer

China
Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects

Healthy Females

United States
Takeda

Terminated

Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes

Glycemic Control

United States, Bulgaria, Malaysia, Korea, Republic of, Australia, Czech Republic, Hungary, Thailand, Italy, Slovakia, Croatia
Takeda

Not yet recruiting

A Study of Maribavir in Chinese Adults With Cytomegalovirus (CMV) Infections

Cytomegalovirus (CMV)

China
Takeda
Takeda Development Center Americas, Inc.

Recruiting

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Children and Teenage Transplant Recipients With CMV Infection

Cytomegalovirus (CMV)

France, United Kingdom, Israel, Germany, Spain, Belgium, Australia, Brazil, China, Japan, United States
Takeda
Takeda Development Center Americas, Inc.

Completed

A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

Angioedema

United States, Spain, Netherlands, Hungary, Italy, Canada, Germany, France, Japan, Poland
Jan Medical, Inc.

Completed

Concussion Testing: A Novel Non-invasive Concussion Detection Device

Concussion

United States
Takeda

Recruiting

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

Sleep Apnea

United States
University of Alberta

Terminated

Lumbar Bracing for People With Type I Modic Changes

Low Back Pain | Magnetic Resonance Imaging | Bone Marrow Edema | Brace | Modic Changes

Canada
Takeda

Active, not recruiting

A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

United States
Juliana Marotti Großhausen

Enrolling by invitation

Fabrication and Insertion of Michigan Splints by Dental Students

Bruxism | Jaw Relationship | Impression Technic, Dental

Switzerland
Shire

Completed

Efficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Millennium Pharmaceuticals, Inc.

Withdrawn

Efficacy and Safety of TAK-653 in Treatment-Resistant Depression

Treatment-Resistant Depression
Takeda

Completed

Safety and Efficacy of TAK-442 in Subjects With Acute Coronary Syndromes

Acute Coronary Syndrome

United States, Belgium, Germany, Bulgaria, India, South Africa, Netherlands, Korea, Republic of, Canada, Chile, Peru, Russian Federation, Argentina, Hungary, Romania, Brazil, Estonia, Serbia, United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of the Potent CYP3A4 Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-906 in Healthy Participants

Healthy Participants

United States
Presage Biosciences
Takeda

Completed

PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC

Head and Neck Squamous Cell Carcinoma

United States
Kirby Institute
AbbVie

Completed

Treatment of Recently Acquired Hepatitis C With the 3D Regimen or G/P (TARGET3D)

Hepatitis C, Acute

United Kingdom, Australia, New Zealand
University of Utah
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD

Hemodialysis | Kidney Disease, Chronic | Kidney Failure | Dialysis | Diabetic | End-stage Kidney Disease | Kidney Dysfunction | Non-diabetic

United States
Takeda

Completed

Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension

Hypertension

Poland, Germany, Bulgaria, Russian Federation, Serbia, Sweden, Netherlands, Estonia, Slovakia, Finland
Takeda

Not yet recruiting

A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN)

Refractory Lupus Nephritis

United States
Takeda
Nimbus Lakshmi, Inc.; Innovaderm Research Inc.

Completed

Study of NDI-034858 in Participants With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

United States, Canada
Takeda

Withdrawn

A Safety and Efficacy Study of Ramelteon Tablets for Sublingual Administration (TAK-375SL) in the Maintenance Treatment of Bipolar 1 Disorder

Bipolar Disorder
Takeda

Completed

Case Control Study of Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure to Lapaquistat Acetate

Toxicity

United States, Argentina, Poland, South Africa, Russian Federation, Netherlands, Chile, Canada, Germany, Latvia, Finland, United Kingdom, Czech Republic, Slovakia
Mayo Clinic

Completed

Tongue Pull Versus Jaw Thrust

Surgery

United States
Milton S. Hershey Medical Center

Completed

Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism

Cataract | Astigmatism

United States
Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers

Phase 1

Belgium
Samsung Medical Center

Recruiting

Peri-treatment of SGLT-2 Inhibitor on Myocardial Infarct Size and Remodeling Index in Patients With Acute Myocardial Infarction and High Risk of Heart Failure Undergoing Percutaneous Coronary Intervention (PRESTIGE-AMI)

Heart Failure | Acute Myocardial Infarction

Korea, Republic of
Novartis Pharmaceuticals

Completed

Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib

Pain

United States
Takeda

Completed

A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone

Essential Hypertension

Italy, Poland, Spain, Bulgaria, Serbia, Netherlands, Estonia, Hungary, Germany, Sweden, Lithuania, Slovakia, United Kingdom, France
Ohio State University Comprehensive Cancer Center
Incyte Corporation; Jazz Pharmaceuticals

Recruiting

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Secondary Acute Myeloid Leukemia | Myeloproliferative Neoplasm

United States
Presage Biosciences
Takeda

Withdrawn

CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia

Solid Tumour

Australia
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
Takeda

Recruiting

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period

Plaque Psoriasis

United States, Canada, Bulgaria, Hungary

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