Search clinical trials for: JNJ-55308942: MAD Part

Total 43 results

Janssen-Cilag International NV

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-55308942 in Healthy Male and Female Participants

Healthy

Belgium
Janssen Cilag N.V./S.A.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects (CHF6333 FIH)

Cystic Fibrosis | Non-Cystic Fibrosis Bronchiectasis

Belgium
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

Tumor or Lymphoma

United States, France, Spain
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma

Neoplasms | Lymphoma | Adenocarcinoma | Esophagogastric Junction

Japan
National University of Singapore
KHANA Center for Population Health Research

Recruiting

Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia

HIV Infections | AIDS

Cambodia
University of Southern Denmark
Central Denmark Region; Region Capital Denmark; Region of Southern Denmark; Copenhagen... and other collaborators

Recruiting

Paediatric Autism Communication Therapy (PACT) in Children With Autism Spectrum Disorder (DAN-PACT)

Autism Spectrum Disorder

Denmark
Janssen-Cilag International NV

Completed

A Positron Emission Tomography (PET) Study to Investigate P2X7 Receptor Occupancy by JNJ-55308942 Using [18F]-JNJ-64413739

Healthy

Belgium
Janssen Pharmaceutica N.V., Belgium

Active, not recruiting

A Study of JNJ-55308942 in the Treatment of Bipolar Depression

Bipolar Disorder

United States, Spain, Poland, Canada
Janssen-Cilag International NV

Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Healthy

Belgium
Tata Memorial Centre
Bhabha Atomic Research Centre (BARC)

Active, not recruiting

Artificial Intelligence in CNS Radiation Oncology (AI-RAD)

CNS Tumor

India
Vanderbilt University
University of Miami; National Institute on Minority Health and Health Disparities... and other collaborators

Completed

Tailoring a Lifestyle Intervention to Address Obesity Disparities Among Men

Obesity | Weight Loss

United States
Cairo University

Unknown

HIIT Versus IMT on Modulating Blood Rheology in CAD Risk Factors

Coronary Artery Disease, Early-Onset

Oman
University of Colorado, Denver

Active, not recruiting

Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes (IMPROVE-T2D)

Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes Complications | Type 2 Diabetes Mellitus | Pediatric Obesity | Diabetic Kidney Disease | Diabetic Nephropathies | Weight Loss | Bariatric Surgery Candidate | Adolescent Obesity | Nephropathy

United States
University of Colorado, Denver

Active, not recruiting

Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study (Renal-HEIR)

Obesity | Type 2 Diabetes Mellitus | Adolescent Obesity | Nephropathy

United States
University of Colorado, Denver

Completed

Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function (CASPER)

Diabetes Mellitus, Type 1 | Diabetic Nephropathies | Type 1 Diabetes Mellitus | Diabetes Mellitus Complication | Nephropathy | Autoimmune Diabetes | Juvenile Diabetes

United States
University of Colorado, Denver
Juvenile Diabetes Research Foundation

Completed

Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance (CROCODILE)

Diabetes Mellitus | Diabetes | Diabetes Complications | Type1diabetes | Type 1 Diabetes | Diabetic Kidney Disease | Diabetic Nephropathies | Type 1 Diabetes Mellitus | Autoimmune Diabetes | Diabetes, Autoimmune | Juvenile Diabetes

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)

Healthy

United States
University of Colorado, Denver

Completed

PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN) (PENGUIN)

Polycystic Kidney, Autosomal Dominant | Polycystic Kidney Disease, Adult

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

Type 2 Diabetes Mellitus | Diabetic Kidney Disease | Adolescent Obesity | Puberty | Pre Diabetes | Kidney Hypoxia

United States
University of Minnesota

Completed

The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients

Cystic Fibrosis

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study) (PANDA)

Diabetes Complications | Type 1 Diabetes | Diabetic Kidney Disease | Diabetic Nephropathies | Autoimmune Diabetes

United States
University of Colorado, Denver

Enrolling by invitation

Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study (HEIRitage)

Obesity | Diabetic Kidney Disease | Diabetic Nephropathies | Type 2 Diabetes | Adolescent Obesity | Nephropathy | Diabetes Type 2

United States
University of Colorado, Denver
University of Michigan; Brigham and Women's Hospital; Boston Medical Center

Recruiting

Renal Mechanism of SGLT2 Inhibition

Diabetic Kidney Disease | Type 2 Diabetes

United States
Janssen Research & Development, LLC

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-61803534 and to Evaluate the Effect of JNJ-61803534 on the Pharmacokinetics of Midazolam in Healthy Participants

Healthy

Belgium
Affiliated Hospital of Jiangnan University

Recruiting

Pamiparib (BGB-290) Was Used in EGFR-TkIs Resistant Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | EGF-R Positive Non-Small Cell Lung Cancer

China
Riyadh Elm University

Not yet recruiting

The Effectiveness of Buccal Infiltration Only Using Articaine for Extraction of Mandibular Molar

Pain
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Multiple-Dose Administration of JNJ-42847922 on Midazolam and Warfarin in Healthy Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants

Healthy

Belgium
AstraZeneca
Eli Lilly and Company

Completed

A Drug-Drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study of Intranasal Esketamine and Its Effects on the Pharmacokinetics of Orally-Administered Midazolam and Bupropion in Healthy Participants

Healthy

Belgium
University Hospital, Clermont-Ferrand

Completed

Validation in French Language of the Questionnaire EARS (EARS)

Chronic Low Back Pain

France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Image-Guided Stereotactic Biopsy of High Grade Gliomas

Glioma | Brain Cancer

United States
Seoul National University Bundang Hospital

Terminated

The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
University of California, San Francisco

Completed

Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients (BufferDent)

Pain

United States
Minia University

Completed

Articaine Efficacy and Safety for Children Below Age of 4-years

Pain | Behaviour Assessment

Egypt
Jaeb Center for Health Research

Recruiting

Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF

Cystic Fibrosis

United States
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Autoimmunity Centers of Excellence

Completed

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

Systemic Lupus Erythematosus (SLE) | Multiple Sclerosis (MS) | Rheumatoid Arthritis (RA) | Juvenile Dermatomyositis (JDM) | Juvenile Idiopathic Arthritis (JIA) | Pemphigus Vulgaris | Systemic Sclerosis (SSc) | Pediatric SLE | Pediatric-Onset Multiple Sclerosis (POMS)

United States
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Malignant Glioma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico, Australia, Canada
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam

Search clinical trials for: JNJ-55308942: MAD Part

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